S-(2-thiopyridyl)mercaptopropionohydrazide
- CAS No.
- 115616-51-8
- Chemical Name:
- S-(2-thiopyridyl)mercaptopropionohydrazide
- Synonyms
- 3-(2-Pyridyldisulfanyl)propanehydrazide;3-(pyridin-2-yldisulfanyl)propanehydrazide;S-(2-thiopyridyl)mercaptopropionohydrazide;3-(2-Pyridyldithio)propionylhydrazide(PDPH);Propanoic acid, 3-(2-pyridinyldithio)-, hydrazide
- CBNumber:
- CB41322297
- Molecular Formula:
- C8H11N3OS2
- Molecular Weight:
- 229.32
- MDL Number:
- MOL File:
- 115616-51-8.mol
| Melting point | 87-90°C |
|---|---|
| Boiling point | 463.6±41.0 °C(Predicted) |
| Density | 1.35±0.1 g/cm3(Predicted) |
| storage temp. | 2-8°C |
| solubility | Chloroform (Slightly), Methanol (Slightly) |
| form | Solid |
| pka | 12.81±0.35(Predicted) |
| color | White |
| Stability | Light Sensitive |
| FDA UNII | 4RHG5J9YPC |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H315-H319 |
| Precautionary statements | P264-P280-P302+P352-P337+P313-P305+P351+P338-P362+P364-P332+P313 |
S-(2-thiopyridyl)mercaptopropionohydrazide price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 803480 | PDPH (3-(2-pyridyldithio)propionyl hydrazide) | 115616-51-8 | 50MG | $312 | 2023-06-20 | Buy |
| TRC | P993040 | 3-(2-Pyridyldithio)propanoicAcidHydrazide | 115616-51-8 | 5mg | $140 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | CHM0009632 | 3-(2-PYRIDYLDITHIO)PROPANOIC ACID HYDRAZIDE 95.00% | 115616-51-8 | 5MG | $774.4 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | CHM0009632 | 3-(2-PYRIDYLDITHIO)PROPANOIC ACID HYDRAZIDE 95.00% | 115616-51-8 | 50MG | $1871.1 | 2021-12-16 | Buy |
S-(2-thiopyridyl)mercaptopropionohydrazide Chemical Properties,Uses,Production
Chemical Properties
White Solid
Uses
A fluorescent sulfhydryl active reagent.
General Description
The PDPH is a heterobifunctional crosslinker containing sulfhydryl-reactive pyridyldithiol and carbonyl-reactive hydrazide moieties. Pyridyldithiols react with free sulfhydryls (-SH) to form disulfide bonds. Hydrazide groups react with carbonyls (aldehydes and ketones) to form stable hydrazone bonds. Aldehyde groups can be created by periodate-oxidation of sialic acid and other sugar components of glycoprotein polysaccharides. Thus, PDPH is useful for conjugating glycoproteins and sulfhydryl-containing peptides or proteins. Likewise, PDPH is useful as a sulfhydryl-addition reagent for glycoproteins and other carbohydrates; after reaction of the hydrazide to an oxidized carbohydrate, the pyridyldithiol group can be cleaved by a reducing agent to expose a sulfhydryl group. Yet another application for PDPH is to react the primary amine of the hydrazide moiety to a carboxyl group using the crosslinker EDC.
S-(2-thiopyridyl)mercaptopropionohydrazide Preparation Products And Raw materials
Raw materials
Preparation Products
S-(2-thiopyridyl)mercaptopropionohydrazide Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| TargetMol Chemicals Inc. | +1-781-999-5354 | support@targetmol.com | United States | 19973 | 58 |
| Jilin Chinese Academy of Sciences-yanshen Technology | +undefined18143011203 | info@chemextension.com | China | 42057 | 58 |
| J & K SCIENTIFIC LTD. | 010-82848833 400-666-7788 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Chemsky（shanghai）International Co.,Ltd. | 021-50135380 | shchemsky@sina.com | China | 32344 | 50 |
| Aikon International Limited | 025-66113011 18112977050 | sales01@aikonchem.com | China | 16028 | 58 |
| Angel Pharmatech, Ltd. | 17317130613 | 3358272972@qq.com | China | 3237 | 58 |
| Hefei Bomei Biotechnology Co., Ltd. | 13739298932 | 531626407@qq.com | China | 3000 | 58 |
| Shenzhen Polymeri Biochemical Technology Co., Ltd. | +86-400-002-6226 13028896684 | sales@rrkchem.com | China | 55717 | 58 |
| Henan Alpha Chemical Co., Ltd. | 0371-55055611 18137792234 | 3002694073@qq.com | China | 10166 | 58 |
| Shaanxi Xinyan Bomei Biotechnology Co., Ltd. | 029-86217788 13892832556 | 2440688701@qq.com | China | 1993 | 58 |