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Isothiazolinones

Description Applications Safety Information
Isothiazolinones
Isothiazolinones structure
CAS No.
26172-55-4
Chemical Name:
Isothiazolinones
Synonyms
CMI;MCI;CMIT;IDAS;mci/mi;CMI/MIT;KATHONFP;KATHONLX;CMIT/MIT;Danisol-K
CBNumber:
CB4132565
Molecular Formula:
C4H4ClNOS
Formula Weight:
149.6
MOL File:
26172-55-4.mol

Isothiazolinones Properties

Melting point:
42-45?C
Boiling point:
109.7°C
Density 
1.25 (14% aq.)
refractive index 
n20/D 1.378
storage temp. 
Refrigerator
pka
-4.06±0.40(Predicted)
Stability:
Stable. Incompatible with strong oxidizing agents.
Indirect Additives used in Food Contact Substances
5-CHLORO-2-METHYL-4-ISOTHIAZOLIN-3-ONE
CAS DataBase Reference
26172-55-4(CAS DataBase Reference)
NIST Chemistry Reference
5-Chloro-2-methyl-3(2h)-isothiazolone(26172-55-4)
EPA Substance Registry System
5-Chloro-2-methyl-4-isothiazolin-3-one (26172-55-4)
SAFETY
  • Risk and Safety Statements
Hazard Codes  C,N,T,Xn
Risk Statements  34-43-50-20/21/22-50/53-23/24/25-42/43
Safety Statements  26-36/37/39-45-60-61-24-28-36/37-23
RIDADR  UN 1760 8/PG 2
WGK Germany  1
RTECS  NX8156850
HazardClass  8
PackingGroup  III

Isothiazolinones price More Price(1)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich PHR1597 CMIT/MIT Pharmaceutical Secondary Standard; Certified Reference Material 26172-55-4 1ml $63.7 2019-12-02 Buy

Isothiazolinones Chemical Properties,Uses,Production

Description

Isothiazolinone is a heterocyclic chemical compound related to isothiazole. Isothiazolinone is an antimicrobial preservative that is often used to control fungi, bacteria, and algae. Since water-containing solutions are the breeding grounds for bacteria, isothiazolinone can easily be used in such solutions.

Applications

Although isothiazolinones have no direct applications, their derivatives such as 5-chloro-2-methyl-4-isothiazolin-3-on and 2-methyl-4-isothiazolin-3 which are used together as preservatives in commercial households and cosmetics products, for instance, cleaners, shampoos, and washing materials. Notably, various products that use isothiazolinones are in the market, including shampoo, hand sanitizer, and lotions. Isothiazolinones is used in these products as an inhibitor of microbial activity that could lead to the product spoiling before the expected expiration date.

Safety Information

The recommended use of isothiazolinone products by the manufacturers used as wrinkle releaser is not harmful. However, allergy to skin is one of the most reported issue with isothiazolinone.

Description

Methy1chloro-isothiazolinone (MCI) is contained, along with methylisothiazolinone (MI), in Kathon cosmetic grade (CG) and MCI/MI. It is irritant and sensitizer.

Chemical Properties

Liquid

Uses

Isocil(R) MW-14 is a high performance biocide for preserving metal working fluids, hydraulic fluids, polymer emulsions, pigment dispersions. Suggested applications: preservative concentrate. Very low level.

Uses

Isocil(R) PC is a cost-effective antimicrobial for personal care formulations. Suggested applications: personal care preservative.

Uses

Isocil(R) RW is a high performance industrial microbiocide for use in recirculating water cooling towers, wood, mold and mildew control, pulp and paper mills, air washer systems. Suggested applications: Industrial water treatment. Very low use levels.

Uses

A isothiazolidin-3-one derivative as antimicrobial. It was tested for inhibition of PCAF activity. 5-Chloroisothiazolinones showed the most potent inhibition of PCAF.

Definition

ChEBI: A 1,2-thiazole that is 4-isothiazolin-3-one bearing a methyl group on the nitrogen atom and a chlorine at C-5. It is a powerful biocide and preservative and is the major active ingredient in the commercial product KathonTM.

Isothiazolinones Preparation Products And Raw materials

Raw materials

Preparation Products


Isothiazolinones Suppliers

Global( 255)Suppliers
Supplier Tel Fax Email Country ProdList Advantage
Hefei TNJ Chemical Industry Co.,Ltd.
0551-65418671
0551-65418697 sales@tnjchem.com CHINA 37442 58
Henan DaKen Chemical CO.,LTD.
+86-371-55531817
info@dakenchem.com CHINA 21711 58
Henan Tianfu Chemical Co.,Ltd.
0371-55170693
0371-55170693 info@tianfuchem.com CHINA 22617 55
Shanghai Time Chemicals CO., Ltd.
+8618017249410 +86-021-57951555
+86-021-57951555 jack.li@time-chemicals.com CHINA 1365 55
Hangzhou FandaChem Co.,Ltd.
0086 158 5814 5714 (Mobile
+86-571-56059825 fandachem@gmail.com CHINA 8463 55
Hefei TNJ Chemical Industry Co.,Ltd.
86-0551-65418684 18949823763
86-0551-65418684 info@tnjchem.com China 2799 55
Tianjin Zhongxin Chemtech Co., Ltd.
022-66880623
022-66880086 sales@tjzxchem.com CHINA 626 58
Shanghai Zheyan Biotech Co., Ltd.
18017610038
zheyansh@163.com CHINA 3623 58
career henan chemical co
+86-371-86658258
sales@coreychem.com CHINA 30021 58
Hubei Jusheng Technology Co.,Ltd.
86-18871470254
027-59599243 linda@hubeijusheng.com CHINA 28230 58

View Lastest Price from Isothiazolinones manufacturers

Image Release date Product Price Min. Order Purity Supply Ability Manufacturer
2020-12-25 5-Chloro-2-methyl-4-isothiazolin-3-one
26172-55-4
US $1.00-100.00 / KG 0.5KG >99% 20tons Anhui Rencheng Technology Co., Ltd
2018-12-18 Isothiazolinones
26172-55-4
US $2.00 / kg 1kg 99% Ask career henan chemical co
2018-08-21 Isothiazolinones
26172-55-4
US $7.00 / KG 1KG 99% 1000KG career henan chemical co

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