6,2',4'-TRIMETHOXYFLAVONE
- CAS No.
- 720675-90-1
- Chemical Name:
- 6,2',4'-TRIMETHOXYFLAVONE
- Synonyms
- Trimethoxyflavone;6,2',4'-Trimethoxyflavone;6,2',4'-TRIMETHOXYFLAVONE;2',4',6-Trimethoxyflavone;2-(2,4-Dimethoxyphenyl)-2,3-dihydro-6-methoxy-4H-1-benzopyran-4-one;4H-1-Benzopyran-4-one, 2-(2,4-dimethoxyphenyl)-2,3-dihydro-6-methoxy-
- CBNumber:
- CB4137595
- Molecular Formula:
- C18H18O5
- Molecular Weight:
- 314.33
- MDL Number:
- MFCD03412381
- MOL File:
- Mol file
- MSDS File:
- SDS
6,2',4'-TRIMETHOXYFLAVONE price More Price(3)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | T4080 | 6, 2′, 4′-trimethoxyflavone ≥98% (HPLC) | 720675-90-1 | 10mg | $90.5 | 2024-03-01 | Buy |
| Sigma-Aldrich | T4080 | 6, 2′, 4′-trimethoxyflavone ≥98% (HPLC) | 720675-90-1 | 50mg | $347 | 2024-03-01 | Buy |
| American Custom Chemicals Corporation | CBL0001131 | 6, 2′, 4′-trimethoxyflavone 95.00% | 720675-90-1 | 250MG | $238.35 | 2021-12-16 | Buy |
6,2',4'-TRIMETHOXYFLAVONE Chemical Properties,Uses,Production
Biochem/physiol Actions
6, 2′, 4′-trimethoxyflavone is a selective aryl hydrocarbon receptor (AHR) antagonist with no partial agonist activity. The role of the transcription factor aryl hydrocarbon receptor (AHR) in biology is still under evaluation and has expanded beyond that of a xenobiotic sensor and regulator of detoxification. Inhibition of AHR activity by antagonists could result in anti-inflammatory actions. 6, 2′, 4′-trimethoxyflavone (TMF) is a pure AHR antagonist. The compound compete with agonists, such as 2, 3, 7, 8-tetrachlorodibenzo-p-dioxin (TCDD) and benzo[a]pyrene (B[a]P), thus effectively inhibiting AHRmediated transactivation of a heterologous reporter and endogenous targets e.g. CYP1A1. TMF also exhibits no species or promoter dependency with regard to AHR antagonism. Thus it represents an improved tool allowing for more precise dissection of AHR function.
6,2',4'-TRIMETHOXYFLAVONE Preparation Products And Raw materials
Raw materials
Preparation Products
6,2',4'-TRIMETHOXYFLAVONE Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Aladdin Scientific | +1-833-552-7181 | sales@aladdinsci.com | United States | 52927 | 58 |
| 3B Pharmachem (Wuhan) International Co.,Ltd. | 821-50328103-801 18930552037 | 3bsc@sina.com | China | 15848 | 69 |
| Sigma-Aldrich | 021-61415566 800-8193336 | orderCN@merckgroup.com | China | 51471 | 80 |
| Supplier | Advantage |
|---|---|
| Aladdin Scientific | 58 |
| 3B Pharmachem (Wuhan) International Co.,Ltd. | 69 |
| Sigma-Aldrich | 80 |