HEXAHYDROCURCUMIN
- CAS No.
- 36062-05-2
- Chemical Name:
- HEXAHYDROCURCUMIN
- Synonyms
- HEXAHYDROCURCUMIN;Hexahydrocurcumin, BR;5-dimethyl ether Gallic Acid;5-dimethoxy-4-hydroxy Benzoic Acid;5-Hydroxy-1,7-bis(4-hydroxy-3-methoxyphenyl)-3-heptanone;1,7-Bis(4-hydroxy-3-methoxyphenyl)-5-hydroxyheptan-3-one;1,7-Bis(3-methoxy-4-hydroxyphenyl)-5-hydroxy-3-heptanone;3-Heptanone, 5-hydroxy-1,7-bis(4-hydroxy-3-methoxyphenyl)-;(RS)-5-Hydroxy-1,7-bis(4-hydroxy-3-methoxyphenyl)-3-heptanone;5-Hydroxy-1-(4-hydroxy-3-Methoxycyclohexyl)-7-(4-hydroxy-3-Methoxyphenyl)heptan-3-one
- CBNumber:
- CB41412369
- Molecular Formula:
- C21H26O6
- Molecular Weight:
- 374.43
- MDL Number:
- MFCD18783096
- MOL File:
- 36062-05-2.mol
| Melting point | 80-82℃ |
|---|---|
| Boiling point | 622.6±55.0 °C(Predicted) |
| Density | 1.226 |
| Flash point | 218℃ |
| storage temp. | 2-8°C |
| solubility | Chloroform (Sparingly), Ethyl Acetate (Slightly), DCM, DMSO |
| pka | 10.02±0.20(Predicted) |
| color | Pale Yellow |
| BRN | 2486876 |
| FDA UNII | RNL5XJ2BA7 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H302-H315-H319-H335 | |||||||||
| Precautionary statements | P261-P280-P301+P312-P302+P352-P305+P351+P338 | |||||||||
| WGK Germany | 3 | |||||||||
| NFPA 704 |
|
HEXAHYDROCURCUMIN price More Price(11)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | SMB01366 | Hexahydrocurcumin ≥95% (HPLC) | 36062-05-2 | 1MG | $124 | 2024-03-01 | Buy |
| Sigma-Aldrich | SMB01366 | Hexahydrocurcumin ≥95% (HPLC) | 36062-05-2 | 10MG | $744 | 2024-03-01 | Buy |
| Sigma-Aldrich | PHL82559 | Hexahydrocurcumin phyproof? Reference Substance | 36062-05-2 | 10MG | $975 | 2024-03-01 | Buy |
| Sigma-Aldrich | 69727 | Hexahydrocurcumin analytical standard | 36062-05-2 | 10mg | $835 | 2024-03-01 | Buy |
| Cayman Chemical | 11714 | Hexahydrocurcumin ≥95% | 36062-05-2 | 1mg | $86 | 2024-03-01 | Buy |
HEXAHYDROCURCUMIN Chemical Properties,Uses,Production
Description
Hexahydrocurcumin is a natural product and glucuronide metabolite of curcumin that has anti-inflammatory, antioxidant, and anticancer properties. It reduces prostaglandin E2 (PGE2) production stimulated by phorbol 12-myristate 13-acetate (PMA; ) by 37% in human colonic epithelial cells when used at a concentration of 20 μM. Hexahydrocurcumin (3.125-25 μM) inhibits overproduction of nitric oxide induced by LPS in RAW 264.7 macrophage cells in a concentration-dependent manner. It does not affect LPS-induced cytokine release but inhibits LPS-induced iNOS and COX-2 upregulation and NF-κB activation when used at a concentration of 50 μM. Hexahydrocurcumin prevents the formation of aberrant crypt foci in a dimethylhydrazine rat model of colon cancer and potentiates the effect of 5-fluorouracil .
Uses
Hexahydrocurcumin is an intermediate in the synthesis of Gingerenone A (G387500) which is an antifungal and antiparasitic diarylheptenone that is isolated from Zingiber officinale (more commonly known as ginger), a medicinal plant that is used to treat inflammation and musculoskeletal disorders.
Definition
ChEBI: Hexahydrocurcumin is a diarylheptanoid.
target
PGE | NOS | COX
HEXAHYDROCURCUMIN Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Chengdu GLP biotechnology Co Ltd | 028-87075086 13350802083 | scglp@glp-china.com | CHINA | 1824 | 58 |
| Chengdu Biopurify Phytochemicals Ltd. | +8618080483897 | sales@biopurify.com | China | 3424 | 58 |
| Shaanxi Pioneer Biotech Co., Ltd . | +8613259417953 | sales@pioneerbiotech.com | China | 3000 | 58 |
| Hubei xin bonus chemical co. LTD | 86-13657291602 | linda@hubeijusheng.com | CHINA | 22968 | 58 |
| Shanghai Standard Technology Co., Ltd. | 18502101150 | ft-sales@nature-standard.com | CHINA | 1923 | 58 |
| Wuhan ChemNorm Biotech Co.,Ltd. | +86-27-8439 4403 18971486879 | sales@chemnorm.com | CHINA | 2935 | 58 |
| Aktin Chemicals, Inc. | 028-85159085 | info@aktinchem.com | CHINA | 1025 | 58 |
| Shanghai UCHEM Inc. | +862156762820 +86-13564624040 | sales@myuchem.com | China | 6710 | 58 |
| Labnetwork lnc. | +86-27-50766799 +8618062016861 | contact@labnetwork.com | China | 19994 | 58 |
| Jiangsu Yongjian Pharmaceutical Co.,Ltd | +86-0523-80183620 +86-17701422015 | 982552664@qq.com | China | 258 | 58 |
View Lastest Price from HEXAHYDROCURCUMIN manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2023-02-24 | Hexahydrocurcumin
36062-05-2
|
US $0.00 / mg | 5mg | ≥98%(HPLC) | 10 g | Shanghai Standard Technology Co., Ltd. | |
 |
2022-10-14 | HEXAHYDROCURCUMIN
36062-05-2
|
US $0.00-0.00 / KG | 1KG | 98% | 1Ton | Henan Aochuang Chemical Co.,Ltd. |
-
- Hexahydrocurcumin
36062-05-2
- US $0.00 / mg
- ≥98%(HPLC)
- Shanghai Standard Technology Co., Ltd.
-
- HEXAHYDROCURCUMIN
36062-05-2
- US $0.00-0.00 / KG
- 98%
- Henan Aochuang Chemical Co.,Ltd.