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4-Quinazolinamine, N-(3-chloro-4-fluorophenyl)-7-fluoro-6-nitro-

4-Quinazolinamine, N-(3-chloro-4-fluorophenyl)-7-fluoro-6-nitro- structure

CAS No.: 162012-67-1

Chemical Name:: 4-Quinazolinamine, N-(3-chloro-4-fluorophenyl)-7-fluoro-6-nitro-

Synonyms: N-(3-chloro-4-fluorophenyl)-7-fluoro-6-nitroquinazolin-4-amine;4-(3-chloro-4-fiuoro-phenylaMino)-7-fluoro-6-nitroquninazoline;N-(3-Chloro-4-fluorophenyl)-7-fluoro-6-nitro-4-quinazolinamine;N-(4-(3-chloro-4-fluorophenyl))-7-fluoro-6nitroquinazolin-4-amine;)-7-fL;Afatinib Impurity 76;Afatinib/Dacomitinib;uoro-6-nitroquninazoL;Afatinib intermediate A;4-(3-chloro-4-fiuoro-phen...

CBNumber:: CB41512555

Molecular Formula:: C14H7ClF2N4O2

Molecular Weight:: 336.68

MDL Number:: MFCD09998825

MOL File:: 162012-67-1.mol

MSDS File:: SDS

Last updated:2023-12-20 20:39:53

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4-Quinazolinamine, N-(3-chloro-4-fluorophenyl)-7-fluoro-6-nitro- Properties

Melting point	242-244℃
Boiling point	489℃
Density	1.616
Flash point	249℃
storage temp.	2-8°C(protect from light)
solubility	DMSO (Slightly), Methanol (Slightly, Sonicated)
form	Solid
pka	5.07±0.70(Predicted)
color	Yellow to Dark Yellow

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS07
Signal word	Warning
Hazard statements	H315-H319
Precautionary statements	P264-P280-P302+P352-P305+P351+P338-P332+P313-P337+P313-P362
HS Code	2933.59.8000

4-Quinazolinamine, N-(3-chloro-4-fluorophenyl)-7-fluoro-6-nitro- price More Price(32)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
TCI Chemical	C3276	N-(3-Chloro-4-fluorophenyl)-7-fluoro-6-nitro-4-quinazolinamine	162012-67-1	5G	$163	2024-03-01	Buy
TCI Chemical	C3276	N-(3-Chloro-4-fluorophenyl)-7-fluoro-6-nitro-4-quinazolinamine	162012-67-1	25G	$486	2024-03-01	Buy
TRC	C376250	4-(3-Chloro-4-fluorophenylamino)-7-fluoro-6-nitroquinazoline	162012-67-1	10g	$970	2021-12-16	Buy
TRC	C376250	4-(3-Chloro-4-fluorophenylamino)-7-fluoro-6-nitroquinazoline	162012-67-1	100mg	$95	2021-12-16	Buy
AK Scientific	B693	4-(3-Chloro-4-fluorophenylamino)-7-fluoro-6-nitroquninazoline	162012-67-1	5g	$98	2021-12-16	Buy

Product number	Packaging	Price	Buy
C3276	5G	$163	Buy
C3276	25G	$486	Buy
C376250	10g	$970	Buy
C376250	100mg	$95	Buy
B693	5g	$98	Buy

4-Quinazolinamine, N-(3-chloro-4-fluorophenyl)-7-fluoro-6-nitro- Chemical Properties,Uses,Production

Uses

4-(3-Chloro-4-fluorophenylamino)-7-fluoro-6-nitroquninazoline is an intermediate in the synthesis of Afatinib (A355300), an aminocrotonylamino-substituted quinazoline derivative used for treating cancer and diseases of the respiratory tract, lungs, gastrointestinal tract, bile duct, and gallbladder.

4-Quinazolinamine, N-(3-chloro-4-fluorophenyl)-7-fluoro-6-nitro- synthesis

Synthesis of 4-Quinazolinamine, N-(3-chloro-4-fluorophenyl)-7-fluoro-6-nitro- from 3-Chloro-4-fluoroaniline and 7-Fluoro-6-nitro-4-hydroxyquinazoline

4-Quinazolinamine, N-(3-chloro-4-fluorophenyl)-7-fluoro-6-nitro- Preparation Products And Raw materials

Raw materials

Preparation Products

N-(3-chloro-4-fluorophenyl)-7-Methoxy-6-aminoquinazolin-4-aMine

4-Quinazolinamine, N-(3-chloro-4-fluorophenyl)-7-fluoro-6-nitro- Suppliers

Global( 342)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Hebei Yanxi Chemical Co., Ltd.	+8617531190177	peter@yan-xi.com	China	5993	58
Capot Chemical Co.,Ltd.	571-85586718 +8613336195806	sales@capotchem.com	China	29797	60
Beijing Cooperate Pharmaceutical Co.,Ltd	010-60279497	sales01@cooperate-pharm.com	CHINA	1811	55
Henan Tianfu Chemical Co.,Ltd.	+86-0371-55170693 +86-19937530512	info@tianfuchem.com	China	21695	55
Hangzhou FandaChem Co.,Ltd.	008657128800458; +8615858145714	fandachem@gmail.com	China	9352	55
Shanghai Yingrui Biopharma Co., Ltd.	+86-21-33585366 - 03@	sales03@shyrchem.com	CHINA	738	60
ATK CHEMICAL COMPANY LIMITED	+undefined-21-51877795	ivan@atkchemical.com	China	32480	60
Anqing Chico Pharmaceutical Co., Ltd.	15380796838	chloewu@chicopharm.cn	CHINA	341	58
career henan chemical co	+86-0371-86658258	sales@coreychem.com	China	29914	58
Zhejiang ZETian Fine Chemicals Co. LTD	18957127338	stella@zetchem.com	China	2141	58

Supplier	Advantage
Hebei Yanxi Chemical Co., Ltd.	58
Capot Chemical Co.,Ltd.	60
Beijing Cooperate Pharmaceutical Co.,Ltd	55
Henan Tianfu Chemical Co.,Ltd.	55
Hangzhou FandaChem Co.,Ltd.	55
Shanghai Yingrui Biopharma Co., Ltd.	60
ATK CHEMICAL COMPANY LIMITED	60
Anqing Chico Pharmaceutical Co., Ltd.	58
career henan chemical co	58
Zhejiang ZETian Fine Chemicals Co. LTD	58

View Lastest Price from 4-Quinazolinamine, N-(3-chloro-4-fluorophenyl)-7-fluoro-6-nitro- manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2023-12-20	N-(4-(3-chloro-4-fluorophenyl))-7-fluoro-6nitroquinazolin-4-amine 162012-67-1	US $0.00-0.00 / kg	1kg	98%	1 ton	Nanjing Fred Technology Co., Ltd
2023-12-09	N-(4-(3-chloro-4-fluorophenyl))-7-fluoro-6nitroquinazolin-4-amine 162012-67-1	US $0.00-0.00 / kg	1kg	99%	50000kg	Hebei Yibangte Import and Export Co. , Ltd.
2023-09-06	N-(3-Chloro-4-fluorophenyl)-7-fluoro-6-nitroquinazolin-4-amine 162012-67-1	US $50.00 / kg	1kg	0.99	20 tons	Hebei Yanxi Chemical Co., Ltd.

N-(4-(3-chloro-4-fluorophenyl))-7-fluoro-6nitroquinazolin-4-amine
162012-67-1
US $0.00-0.00 / kg
98%
Nanjing Fred Technology Co., Ltd

N-(4-(3-chloro-4-fluorophenyl))-7-fluoro-6nitroquinazolin-4-amine
162012-67-1
US $0.00-0.00 / kg
99%
Hebei Yibangte Import and Export Co. , Ltd.

N-(3-Chloro-4-fluorophenyl)-7-fluoro-6-nitroquinazolin-4-amine
162012-67-1
US $50.00 / kg
0.99
Hebei Yanxi Chemical Co., Ltd.

4-Quinazolinamine, N-(3-chloro-4-fluorophenyl)-7-fluoro-6-nitro- Spectrum

4-Quinazolinamine, N-(3-chloro-4-fluorophenyl)-7-fluoro-6-nitro-(162012-67-1)¹HNMR

162012-67-1(4-Quinazolinamine, N-(3-chloro-4-fluorophenyl)-7-fluoro-6-nitro-)Related Search:

N-(3-chloro-4-fluorophenyl)-7-Methoxy-6-nitroquinazolin-4-aMine Aprepitant methyl(E)-4-(methylamino)but-2-enoate (2R,3S)-2-[(1R)-1-[3,5-Bis(trifluoroMethyl)phenyl]ethoxy]-3-(phenyl)Morpholine hydrochloride (2S,3R)-2-((S)-1-(3,5-bis(trifluoroMethyl)phenyl)ethoxy)-3-(4-fluorophenyl)Morpholine

TRANS-4-AMINOCROTONIC ACID 7-Fluoro-4-quinazolone Afatinib impurity 45 Benzyl dihydrogen phosphate (2R,3R)-2-[(1R)-1-[3,5-Bis(trifluoroMethyl)phenyl]ethoxy]-3-(4-fluorophenyl)Morpholine

trans-4-Dimethylaminocrotonic acid hydrochloride (S)-N4-(3-chloro-4-fluorophenyl)-7-(tetrahydrofuran-3-yloxy)quinazoline-4,6-diaMine Afatinib Afatinib dimaleate (S)-(+)-3-Hydroxytetrahydrofuran

Afatinib (BIBW 2992) 7-Fluoro-6-nitro-4-hydroxyquinazoline 4-QuinazolinaMine, N-(3-chloro-4-fluorophenyl)-6-nitro-7-[[(3S)-tetrahydro-3-furanyl]oxy]-

1of4

4-Quinazolinamine, N-(3-chloro-4-fluorophenyl)-7-fluoro-6-nitro- 4-(3-chloro-4-fiuoro-phen... N-(3-chloro-4-fluorophenyl)-N-(7-fluoro-6-nitroquinazolin-4-yl)acetaMide (3-Chloro-4-fluorophenyl)(7-fluoro-6-nitroquinazolin-4-yl)amine Afatinib intermediate A 3-Chloro-4-fluorophenyl)(7-fluoro-6-nitroquinazolin-4-yl) N-(3-chloro-4-fluorophenyl)-7-fiuoro-6-nitro-4-quinazolinaMine N-(3-Chloro-4-fluorophenyl)-7-fluoro-6-nitro-4-quinazolinamine (3-Chloro-4-fluorophenyl)(7-fluoro-6-nitroquinazolin-4-yl)amine Afatinib int-1 N-(3-Chloro-4-fluorophenyl)-7-fluoro-6-nitro-4-quinazolinamine N-(3-Cl-4-F-phenyl)-7-F-6-NO2-4-quinazolinamine 4-Quizolimine, N-(3-chloro-4-fluorophenyl)-7-fluoro-6-nitro- 4-[(3-Chloro-4-fluorophenyl)amino]-7-fluoro-6-nitroquinazoline Afatinib Impurity 76 N-(3-chloro-4-fluorophenyl)-7-fluoro-6-nitro quinazoline-4-amine N-(3-chloro-4-fluorophenyl)-7-fluoro-6-nitroquninazoline uoro-6-nitroquninazoL )-7-fL 4- quinazoline amine, N- (3-chloro-4-fluorophenyl) -7-fluoro-6-nitro - 4-(3-Chloro-4-fluoroanilino)-7-fluoro-6-nitroquinazoline 4-Quinazolinamine, N-(3-chloro-4-fluorophenyl)-7-fluoro-6-nitro- ISO 9001：2015 REACH N-(3-chloro-4-fluorophenyl)-7-fluoro-6-nitro- 4-Quinazolinamine, N-(3-chloro-4-fluorophenyl)-7-fluoro-6-ni... Afatinib/Dacomitinib N-(3-chloro-4-fluorophenyl)-7-fluoro-6-nitroquinazolin-4-amine 4-(3-chloro-4-fiuoro-phenylaMino)-7-fluoro-6-nitroquninazoline N-(3-Chloro-4-fluorophenyl)-7-fluoro-6-nitro-4-quinazolinamine N-(4-(3-chloro-4-fluorophenyl))-7-fluoro-6nitroquinazolin-4-amine N - (3-chloro-4-fluorophenyl) -7-fluoro-6-nitro-4-quinazoline amine 162012-67-1 C14H7ClF2N4O2 API intermediates 162012-67-1