Chinese Japanese Germany Korea


1,8-Bis(dimethylamino)naphtalene structure
Chemical Name:
Molecular Formula:
Formula Weight:
MOL File:

1,8-Bis(dimethylamino)naphtalene Properties

Melting point:
49-51 °C(lit.)
Boiling point:
144-145°C (3.7505 mmHg)
Flash point:
>230 °F
storage temp. 
Soluble in organic solvents.
Crystalline Powder
12.1(at 25℃)
Pale brownish-pink
Water Solubility 
Light Sensitive
CAS DataBase Reference
20734-58-1(CAS DataBase Reference)
NIST Chemistry Reference
1,8-Naphthalenediamine, N,N,N',N'-tetramethyl-(20734-58-1)
  • Risk and Safety Statements
  • Hazard and Precautionary Statements (GHS)
Hazard Codes  Xn,C
Risk Statements  22-36/37/38-34
Safety Statements  26-45-36/37/39
RIDADR  3259
WGK Germany  3
HazardClass  8
HS Code  29215900
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning P264, P270, P301+P312, P330, P501
H314 Causes severe skin burns and eye damage Skin corrosion/irritation Category 1A, B, C Danger P260,P264, P280, P301+P330+ P331,P303+P361+P353, P363, P304+P340,P310, P321, P305+ P351+P338, P405,P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning P264, P280, P302+P352, P321,P332+P313, P362
H318 Causes serious eye damage Serious eye damage/eye irritation Category 1 Danger P280, P305+P351+P338, P310
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning
Precautionary statements:
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P301+P330+P331 IF SWALLOWED: Rinse mouth. Do NOT induce vomiting.
P303+P361+P353 IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P405 Store locked up.
P501 Dispose of contents/container to..…

1,8-Bis(dimethylamino)naphtalene price More Price(9)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 14795 N,N,N′,N′-Tetramethyl-1,8-naphthalenediamine purum, ≥99.0% (NT) 20734-58-1 10g $46.8 2018-11-13 Buy
Sigma-Aldrich 14795 N,N,N′,N′-Tetramethyl-1,8-naphthalenediamine purum, ≥99.0% (NT) 20734-58-1 50g $158 2018-11-13 Buy
TCI Chemical B1018 1,8-Bis(dimethylamino)naphthalene [for Dehydrohalogenation] >98.0%(GC)(T) 20734-58-1 1g $31 2018-11-22 Buy
TCI Chemical B1018 1,8-Bis(dimethylamino)naphthalene [for Dehydrohalogenation] >98.0%(GC)(T) 20734-58-1 5g $60 2018-11-22 Buy
Alfa Aesar L00313 1,8-Bis(dimethylamino)naphthalene, 98+% 20734-58-1 50g $117 2018-11-13 Buy

1,8-Bis(dimethylamino)naphtalene Chemical Properties,Uses,Production

Chemical Properties

1,8-Bis(dimethylamino)naphtalene is pale brownish-pink crystalline powder


1,8-Bis(dimethylamino)naphthalene, also referred to as protone sponge, is a lipophilic proton trapping agent. 1,8-Bis(dimethylamino)naphthalene is used in the matrix for mass spectroscopy analysis of lipids and fatty acids.


Very strong base in organic synthesis and catalysis.

Purification Methods

It is prepared by methylating 1,8-diaminonaphthalene, and likely impurities are methylated products. The tetramethyl compound is a stronger base than the unmethylated, di and trimethylated derivatives. The pKa values are: 1,8-(NH2)2 = 4.61, 1,8-(NHMe)2 = 5.61, 1-NHMe-8-NHMe2 = 6.43 and 1,8-(NMe2)2 = 12.34. The mixture is then treated with H2O at pH 8 (where all but the required base are protonated) and extracted with Et2O or CHCl3. The dried extract (K2CO3) yields the tetramethyldiamine on evaporation which can be distilled. It is a strong base with weak nucleophilic properties, e.g. it could not be alkylated by refluxing with EtI in MeCN for 4 days; and on treatment with methyl fluorosulfonate only the fluorosulfonate salt of the base is obtained. [NMR: Adler et al. J Chem Soc, Chem Commun 723 1968, Brown & Letang J Am Chem Soc 63 358 1941, Brzezinski et al. J Chem Soc Perkin Trans 2 857 1991.] Alternatively, crystallise proton sponge from EtOH and dry it in a vacuum oven. Store it in the dark in a CO2-free atmosphere. [Benoit et al. Can J Chem 65 996 1987, Beilstein 13 IV 344.]

1,8-Bis(dimethylamino)naphtalene Preparation Products And Raw materials

Raw materials

Preparation Products

1,8-Bis(dimethylamino)naphtalene Suppliers

Global( 166)Suppliers
Supplier Tel Fax Email Country ProdList Advantage
Capot Chemical Co.,Ltd.
+86 (0)571-855 867 18
+86 (0)571-858 647 95 China 19917 60
Mainchem Co., Ltd.
+86-0592-6210733 CHINA 32447 55
Nanjing ChemLin Chemical Industry Co., Ltd.
025-83697070; CHINA 3015 60
Anhui Royal Chemical Co., Ltd.
+86-025-86736275 CHINA 488 55
Changzhou Ansciep Chemical Co., Ltd.
+86 519 86305871
+86 519 86305879 CHINA 4310 58
Accela ChemBio Inc.
(+1)-858-876-1948 United States 12231 58
Hubei xin bonus chemical co. LTD
027-59338440 CHINA 23049 58
Taizhou FRIEND Chemical Co., Ltd. 0523-86200082
0523-86200991 China 214 55
Shijiazhuang Sdyano Fine Chemical Co., Ltd. 13582355795
4000311741 China 3876 65
Shanghai Wei Nie Chemical Technology Co., Ltd. 13046668259 CHINA 51 58

1,8-Bis(dimethylamino)naphtalene Spectrum

20734-58-1(1,8-Bis(dimethylamino)naphtalene)Related Search:

Copyright 2017 © ChemicalBook. All rights reserved