Chymotrypsin
- CAS No.
- 9004-07-3
- Chemical Name:
- Chymotrypsin
- Synonyms
- α-Chymotrypsin;A-CHYMOTRYPSIN;EC 3.4.21.1;ALPHA-CHYMOTRYPSIN;quimar;zolyse;zolyes;D03484;chymar;ec3445
- CBNumber:
- CB4167554
- Molecular Formula:
- N/A
- Molecular Weight:
- 0
- MDL Number:
- MFCD00130481
- MOL File:
- Mol file
- MSDS File:
- SDS
| Melting point | 127°C |
|---|---|
| Density | 1.37[at 20℃] |
| vapor pressure | 0Pa at 25℃ |
| storage temp. | -20°C |
| solubility | Reconstitute in 1mM HCl. Soluble at 10mg/ml in 1mM HCl. 2mM calcium chloride serves as a stabilizer. Store aliquoted solutions at -20°C for up to a week. |
| form | salt-free, lyophilized powder |
| color | white |
| Water Solubility | 125g/L at 25℃ |
| Merck | 13,2282 |
| LogP | -1.3 at 20℃ |
| EWG's Food Scores | 1-2 |
| FDA UNII | BVS505O332 |
| ATC code | B06AA04,S01KX01 |
| EPA Substance Registry System | Chymotrypsin (9004-07-3) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |   GHS07,GHS08 |
|---|---|
| Signal word | Danger |
| Hazard statements | H315-H317-H319-H334-H335 |
| Precautionary statements | P280-P302+P352-P305+P351+P338 |
| Hazard Codes | Xn,B |
| Risk Statements | 36/37/38-42/43-42 |
| Safety Statements | 26-36-36/37-24-22 |
| WGK Germany | 3 |
| RTECS | GC3050000 |
| F | 3-10 |
| TSCA | Yes |
| HS Code | 35079090 |
Chymotrypsin price More Price(38)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | SRP6509 | Chymotrypsin from human pancreas ≥95% (SDS-PAGE) | 9004-07-3 | 100μg | $428 | 2024-03-01 | Buy |
| Sigma-Aldrich | CHY5S | α-Chymotrypsin from bovine pancreas ≥40?units/mgprotein,vialof5?mg | 9004-07-3 | 10vials | $310 | 2024-03-01 | Buy |
| Sigma-Aldrich | C9134 | α-Chymotrypsin−Agarose from bovine pancreas lyophilized powder, 2,000-3,500?units/g agarose (One ml gel will yield 65-120?units) | 9004-07-3 | 50units | $327 | 2024-03-01 | Buy |
| Sigma-Aldrich | C9134 | α-Chymotrypsin−Agarose from bovine pancreas lyophilized powder, 2,000-3,500?units/g agarose (One ml gel will yield 65-120?units) | 9004-07-3 | 100units | $582 | 2024-03-01 | Buy |
| Sigma-Aldrich | C8946 | α-Chymotrypsin from human pancreas lyophilized powder | 9004-07-3 | 1VIAL | $688 | 2024-03-01 | Buy |
Chymotrypsin Chemical Properties,Uses,Production
Chemical Properties
Lyophilized powder, dialyzed
Uses
The enzyme from Sigma has been used to assess the effect of limited proteolysis with α-chymotrypsin on the sperm penetration.
Uses
α-Chymotrypsin from bovine pancreas has been used in a study to investigate protein extraction by Winsor-III microemulsion systems. α-Chymotrypsin from bovine pancreas has also been used in a study to investigate a new specific fullerene-based fluorescent probe for trypsin.
Uses
α-Chymotrypsin from bovine has been used in a study to inform proteasome inhibition in order to advance anticancer research. α-Chymotrypsin from bovine has also been used in a study that functionalized surface anchored poly(methylhydrosiloxane) thin films on oxidized silicon wafers.
General Description
Chymotrypsin (Chymar) is extractedfrom mammalian pancreas and is used in cataractsurgery. A dilute solution is used to irrigate the posteriorchamber of the eye to dissolve the fine filaments that holdthe lens.
Biochem/physiol Actions
α-Chymotrypsin is a serine peptidase and has 241 amino acid residues contained in three polypeptide chains (A chain-13 residues, B chain-131 residues, and C chain-97 residues) linked by disulfide bridges. Molecular weight of this enzyme is found to be 25 kDa. Its pI is 8.75. It selectively hydrolyzes peptide bonds on the C-terminal side of tyrosine, phenylalanine, tryptophan, and leucine. Ca2+ activates and stabilizes the enzyme. The enzyme is inhibited by diisopropyl fluorophosphate (DFP), phenylmethanesulfonyl fluoride (PMSF), N-p-tosyl-L-phenylalanine chloromethyl ketone (TPCK), chymostatin, aprotinin, α1-antitrypsin, α2-macroglobulin, 10 mM Cu2+ and Hg2+.
Purification Methods
α-Chymotrypsin is crystallised twice from four-tenths saturated ammonium sulfate solution, then dissolved in 1mM HCl and dialysed against 1mM HCl at 2-4o. The solution is stored at 2o [Lang et al. J Am Chem Soc 80 4923 1958].
Chymotrypsin Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| BINBO BIOLOGICAL CO.,LTD | +8618629063126 | info@binbobiological.com | China | 224 | 58 |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21695 | 55 |
| career henan chemical co | +86-0371-86658258 | sales@coreychem.com | China | 29914 | 58 |
| Hubei xin bonus chemical co. LTD | 86-13657291602 | linda@hubeijusheng.com | CHINA | 22968 | 58 |
| Chongqing Chemdad Co., Ltd | +86-023-61398051 +8613650506873 | sales@chemdad.com | China | 39916 | 58 |
| Zhengzhou Alfa Chemical Co.,Ltd | +8618530059196 | sale04@alfachem.cn | China | 12431 | 58 |
| Creative Enzymes | 1-516-855-7709 | info@creative-enzymes.com | United States | 8748 | 58 |
| Hefei TNJ Chemical Industry Co.,Ltd. | 0551-65418671 | sales@tnjchem.com | China | 34572 | 58 |
| Handan Tongyi New Material Technology Co., Ltd | +8617330042575 | ty003@handantongyi.com | China | 364 | 58 |
| ANHUI WITOP BIOTECH CO., LTD | +8615255079626 | eric@witopchemical.com | China | 23556 | 58 |
View Lastest Price from Chymotrypsin manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2024-04-11 | Chymotrypsin
9004-07-3
|
US $0.00 / kg | 1kg | 99.8% | 1000 kg | BINBO BIOLOGICAL CO.,LTD | |
 |
2021-12-10 | Chymotrypsin
9004-07-3
|
US $10.00 / ASSAYS | 1ASSAYS | 99.9% | 8000kgs/month | Handan Tongyi New Material Technology Co., Ltd | |
 |
2021-10-20 | Chymotrypsin
9004-07-3
|
US $78.00-65.00 / KG | 1KG | 99% | 9000kg/per week | Hebei Lingding Biotechnology Co., Ltd. |
-
- Chymotrypsin
9004-07-3
- US $0.00 / kg
- 99.8%
- BINBO BIOLOGICAL CO.,LTD
-
- Chymotrypsin
9004-07-3
- US $10.00 / ASSAYS
- 99.9%
- Handan Tongyi New Material Technology Co., Ltd
-
- Chymotrypsin
9004-07-3
- US $78.00-65.00 / KG
- 99%
- Hebei Lingding Biotechnology Co., Ltd.