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1,8-Dihydroxyanthraquinone

1,8-Dihydroxyanthraquinone
1,8-Dihydroxyanthraquinone structure
CAS No.
117-10-2
Chemical Name:
1,8-Dihydroxyanthraquinone
Synonyms
LTAN;ALTAN;Istin;Duolax;Modane;prugol;roydan;Danivac;DANTRON;ISTIZIN
CBNumber:
CB4173988
Molecular Formula:
C14H8O4
Formula Weight:
240.21
MOL File:
117-10-2.mol

1,8-Dihydroxyanthraquinone Properties

Melting point:
191-193 °C(lit.)
Boiling point:
342.92°C (rough estimate)
Density 
1.3032 (rough estimate)
refractive index 
1.5430 (estimate)
Flash point:
>200°C
storage temp. 
Refrigerator
form 
Powder
color 
Orange-brown or brown
Water Solubility 
insoluble
Merck 
14,2815
BRN 
2054727
CAS DataBase Reference
117-10-2(CAS DataBase Reference)
NIST Chemistry Reference
1,8-Dihydroxyanthraquinone(117-10-2)
EPA Substance Registry System
9,10-Anthracenedione, 1,8-dihydroxy-(117-10-2)
SAFETY
  • Risk and Safety Statements
  • Hazard and Precautionary Statements (GHS)
Hazard Codes  Xn
Risk Statements  40
Safety Statements  36/37-36-22
RIDADR  2811
WGK Germany  1
RTECS  CB6650000
TSCA  Yes
HazardClass  IRRITANT
HS Code  29146990
Toxicity LD50 orally in mice: <7 g/kg (Case)
Symbol(GHS):
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning P264, P280, P305+P351+P338,P337+P313P
H320 Causes eye irritation Serious eye damage/eye irritation Category 2B Warning P264, P305+P351+P338,P337+P313
H351 Suspected of causing cancer Carcinogenicity Category 2 Warning P201, P202, P281, P308+P313, P405,P501
Precautionary statements:
P201 Obtain special instructions before use.
P202 Do not handle until all safety precautions have been read and understood.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P281 Use personal protective equipment as required.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P308+P313 IF exposed or concerned: Get medical advice/attention.
P405 Store locked up.
P501 Dispose of contents/container to..…

1,8-Dihydroxyanthraquinone price More Price(6)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich D108103 1,8-Dihydroxyanthraquinone 96% 117-10-2 100g $44.4 2018-11-13 Buy
Sigma-Aldrich D108103 1,8-Dihydroxyanthraquinone 96% 117-10-2 500g $137 2018-11-13 Buy
TCI Chemical D0563 Chrysazin >98.0%(T) 117-10-2 25g $56 2018-11-22 Buy
Alfa Aesar A12001 1,8-Dihydroxyanthraquinone, 95% 117-10-2 500g $113 2018-11-13 Buy
Alfa Aesar A12001 1,8-Dihydroxyanthraquinone, 95% 117-10-2 100g $40.3 2018-11-13 Buy

1,8-Dihydroxyanthraquinone Chemical Properties,Uses,Production

Chemical Properties

orange-brown or brown powder

Chemical Properties

Red-orange to orange crystalline powder or reddish-brown crystalline solid.

Uses

Important intermediate in the manufacture of alizarin and indanthrene dyestuffs; forms insoluble Ca, Ba, Pb lakes. Antioxidant in synthetic lubricants; fungicide.

Uses

Used as a stimulant laxative, though due to its carcinogenic properties, is not widely prescribed.

Uses

cathartic

Definition

ChEBI: A dihydroxyanthraquinone that is anthracene-9,10-dione substituted by hydroxy groups at positions 1 and 8.

brand name

Dorbane (3M Pharmaceuticals); Istizin (Sterling Winthrop);Doss;Normax;Regulex-d.

World Health Organization (WHO)

Dantron, an anthroquinone derivative, has been available for over twenty years and is widely used as a laxative. The results of two chronic toxicity studies in rodents, published in 1985 and 1986, have shown that administration of high doses is associated with the development of intestinal and liver tumours.

General Description

Orange crystalline powder. Almost odorless and tasteless.

Air & Water Reactions

Insoluble in water.

Reactivity Profile

1,8-Dihydroxyanthraquinone is incompatible with strong reducing substances such as hydrides, nitrides, alkali metals, and sulfides.

Fire Hazard

Flash point data for 1,8-Dihydroxyanthraquinone are not available; however, 1,8-Dihydroxyanthraquinone is probably combustible.

Safety Profile

Confirmed carcinogen with experimental carcinogenic data. Moderately toxic by intraperitoneal route. An eye irritant. Questionable carcinogen with experimental carcinogenic and neoplastigenic data. Human mutation data reported. A laxative. When heated to decomposition it emits acrid smoke and irritating fumes.

Potential Exposure

A potential liver carcinogen and possible narcotic, this compound is no longer sold or marketed in the United States Nervous system toxin-acute effects; Respiratory toxin-acute effects other than severe or moderate irritation; Liver-acute effects; Eye irritant-mild.

First aid

Move victim to fresh air. Call 911 or emergency medical service. Give artificial respiration if victim is not breathing. Do not use mouth-to-mouth method if victim ingested or inhaled the substance; give artificial respiration with the aid of a pocket mask equipped with a one-way valve or other proper respira- tory medical device. Administer oxygen if breathing is difficult. Remove and isolate contaminated clothing and shoes. In case of contact with substance, immediately flushskinoreyeswithrunningwaterforatleast20min- utes. For minor skin contact, avoid spreading material on unaffected skin. Keep victim warm and quiet. Effects of exposure (inhalation, ingestion, or skin contact) to substance may be delayed. Ensure that medical personnel are aware of the material(s) involved and take pre- cautions to protect themselves. Medical observation is recommended for 24 to 48 hours after breathing overex- posure, as pulmonary edema may be delayed. As first aid forpulmonaryedema,adoctororauthorizedparamedic may consider administering a drug or other inhalation therapy.

Shipping

UN2811 Toxic solids, organic, n.o.s., Hazard Class: 6.1; Labels: 6.1-Poisonous materials, Technical Name Required.

Purification Methods

Crystallise Danthrone from EtOH and sublime it in a vacuum. [Beilstein 8 IV 3217.]

Incompatibilities

Keep away from strong reducing agents, such as hydrides, nitrides, alkali metals, and sulfides.

Waste Disposal

It is inappropriate and possibly dangerous to the environment to dispose of expired or waste drugs and pharmaceuticals by flushing them down the toilet or discarding them to the trash. Household quantities of expired or waste pharmaceuticals may be mixed with wet cat litter or coffee grounds, double- bagged in plastic, discard in trash. Larger quantities shall carefully take into consideration applicable DEA, EPA, and FDA regulations. If possible return the pharmaceutical to the manufacturer for proper disposal being careful to prop- erly label and securely package the material. Alternatively, the waste pharmaceutical shall be labeled, securely packaged and transported by a state licensed medical waste contractor to dispose by burial in a licensed hazardous or toxic waste landfill or incinerator.

1,8-Dihydroxyanthraquinone Preparation Products And Raw materials

Raw materials

Preparation Products


1,8-Dihydroxyanthraquinone Suppliers

Global( 223)Suppliers
Supplier Tel Fax Email Country ProdList Advantage
Hi-Tech Chemistry Corp
0519-86626038
yuhh@hitechem.com CHINA 811 58
Mainchem Co., Ltd.
+86-0592-6210733
+86-0592-6210733 sales@mainchem.com CHINA 32457 55
Chengdu Biopurify Phytochemicals Ltd.
18080483897
maggie@biopurify.com CHINA 2236 58
Chemwill Asia Co.,Ltd.
86-21-51086038
86-21-51861608 chemwill_asia@126.com;sales@chemwill.com;chemwill@hotmail.com;chemwill@gmail.com CHINA 24001 58
Hubei Jusheng Technology Co.,Ltd.
86-188-71490254
peter@hubeijusheng.com CHINA 20095 58
Kono Chem Co., Ltd
+86-132 8924 6953
info@konochemical.com CHINA 2144 58
Shanghai Zheyan Biotech Co., Ltd.
18017610038
zheyansh@163.com CHINA 3623 58
career henan chemical co
+86-371-86658258
sales@coreychem.com CHINA 19923 58
J & K SCIENTIFIC LTD. 400-666-7788 +86-10-82848833
+86-10-82849933 jkinfo@jkchemical.com;market6@jkchemical.com China 96815 76
Meryer (Shanghai) Chemical Technology Co., Ltd. +86-(0)21-61259100(Shanghai) +86-(0)755-86170099(ShenZhen) +86-(0)10-62670440(Beijing)
+86-(0)21-61259102(Shanghai) +86-(0)755-86170066(ShenZhen) +86-(0)10-88580358(Beijing) sh@meryer.com China 40277 62

View Lastest Price from 1,8-Dihydroxyanthraquinone manufacturers

Image Release date Product Price Min. Order Purity Supply Ability Manufacturer
2018-08-10 1,8-Dihydroxyanthraquinone
117-10-2
US $1.00 / KG 1KG 98%-100% 1 career henan chemical co

1,8-Dihydroxyanthraquinone Spectrum


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