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CALYCOSIN

CAS No.
20575-57-9
Chemical Name:
CALYCOSIN
Synonyms
Clycosin;CALYCOSIN;CALYCOSIN(SH);Astraisoflavone;Calycosin 20575-57-9;Calycosin (Cyclosin);3'-HYDROXYFORMONONETIN;Calycosin >=98% (HPLC);Balofloxacin Impurity 8;3',7-DIHYDROXY-4'-METHOXYISOFLAVONE
CBNumber:
CB4182878
Molecular Formula:
C16H12O5
Molecular Weight:
284.26
MDL Number:
MFCD00210598
MOL File:
20575-57-9.mol
Last updated:2023-08-15 13:09:01

CALYCOSIN Properties

Melting point 245~247℃
Boiling point 536.8±50.0 °C(Predicted)
Density 1.420±0.06 g/cm3(Predicted)
storage temp. Sealed in dry,2-8°C
solubility methanol: soluble1mg/mL, clear, colorless
pka 6.94±0.20(Predicted)
form powder
color white to light yellow
InChIKey ZZAJQOPSWWVMBI-UHFFFAOYSA-N
FDA UNII 09N3E8P7TA

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS06
Signal word  Danger
Hazard statements  H301
Precautionary statements  P301+P310
Hazard Codes  T
Risk Statements  25
Safety Statements  45
RIDADR  UN 3462 6.1 / PGIII
WGK Germany  3
HS Code  2932996560
NFPA 704
0
2 0

CALYCOSIN price More Price(44)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich PHL82491 Calycosin phyproof? Reference Substance 20575-57-9 10mg $629 2024-03-01 Buy
Sigma-Aldrich 1087472 Calycosin United States Pharmacopeia (USP) Reference Standard 20575-57-9 50mg $303 2024-03-01 Buy
Cayman Chemical 25091 Calycosin ≥98% 20575-57-9 5mg $81 2024-03-01 Buy
Cayman Chemical 25091 Calycosin ≥98% 20575-57-9 10mg $152 2024-03-01 Buy
Sigma-Aldrich B9938 Calycosin ≥98% (HPLC) 20575-57-9 10mg $350 2024-03-01 Buy
Product number Packaging Price Buy
PHL82491 10mg $629 Buy
1087472 50mg $303 Buy
25091 5mg $81 Buy
25091 10mg $152 Buy
B9938 10mg $350 Buy

CALYCOSIN Chemical Properties,Uses,Production

Definition

Calycosin is an O-methylated isoflavone. It can be isolated from Astragalus membranaceus Bge. var. mongholicus and Trifolium pratense L. Calycosin is a member of the class of 7-hydroxyisoflavones that is 7-hydroxyisoflavone which is substituted by an additional hydroxy group at the 3' position and a methoxy group at the 4' position. It has a role as a metabolite and an antioxidant. It is a member of 7-hydroxyisoflavones and a member of 4'-methoxyisoflavones. It derives from an isoflavone. It is a conjugate acid of a calycosin(1-).

Pharmaceutical Properties

The potential pharmaceutical properties of calycosin in the treatment of tumors, inflammation, stroke, and cardiovascular diseases have gained increasing attention in the recent years. The literature survey showed that calycosin exhibits promising effects for the treatment of several diseases and that these effects may be due to its isoflavonoid and phytoestrogenic properties. The effects of calycosin most likely result from its interaction with the ER receptors on the cell membrane and the modulation of the MAPK signaling pathway.
Through its effect on this pathway, calycosin can regulate several cell activities, such as apoptosis and angiogenesis, which enables its therapeutic functions. 

Uses

Calycosin is a known antioxidant that prevent redox imbalance in organisms. Also, it possesses anti-tumor, anti-inflammation and osteogenic properties; Useful as a therapeutic reagent for bone loss-associated diseases.

Definition

ChEBI: Calycosin is a member of the class of 7-hydroxyisoflavones that is 7-hydroxyisoflavone which is substituted by an additional hydroxy group at the 3' position and a methoxy group at the 4' position. It has a role as a metabolite and an antioxidant. It is a member of 7-hydroxyisoflavones and a member of 4'-methoxyisoflavones. It is functionally related to an isoflavone. It is a conjugate acid of a calycosin(1-).

CALYCOSIN Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 225)Suppliers
Supplier Tel Email Country ProdList Advantage
Henan Bao Enluo International TradeCo.,LTD
+86-17331933971 +86-17331933971 deasea125996@gmail.com China 2503 58
Hangzhou FandaChem Co.,Ltd.
008657128800458; +8615858145714 fandachem@gmail.com China 9348 55
Shanghai Zheyan Biotech Co., Ltd.
18017610038 zheyansh@163.com CHINA 3620 58
Chengdu Greenpure Biopharma CO.,Ltd
18283602253 jancyzheng@gcgreenpure.com China 952 58
career henan chemical co
+86-0371-86658258 sales@coreychem.com China 29914 58
Chengdu GLP biotechnology Co Ltd
028-87075086 13350802083 scglp@glp-china.com CHINA 1824 58
Chengdu Biopurify Phytochemicals Ltd.
+8618080483897 sales@biopurify.com China 3424 58
Nanjing Dolon Biotechnology Co.,Ltd.
18905173768 sales@dolonchem.com CHINA 2972 58
Hebei Guanlang Biotechnology Co., Ltd.
+86-19930503282 alice@crovellbio.com China 8823 58
Xi'an Kono chem co., Ltd.,
029-86107037 13289246953 info@konochemical.com China 2995 58

Related articles

View Lastest Price from CALYCOSIN manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Calycosin pictures 2024-04-24 Calycosin
20575-57-9
US $100.00-30.00 / kg 1kg 99.93% 1000kg per week Ouhuang Engineering Materials (Hubei) Co., Ltd
CALYCOSIN pictures 2024-04-24 CALYCOSIN
20575-57-9
US $510.00-470.00 / Grams 10Grams 99.99% 100Tons Hebei Dangtong Import and export Co LTD
CALYCOSIN pictures 2023-08-15 CALYCOSIN
20575-57-9
US $50.00 / kg 1kg 99.9% 10000MT Henan Bao Enluo International TradeCo.,LTD
  • Calycosin pictures
  • Calycosin
    20575-57-9
  • US $100.00-30.00 / kg
  • 99.93%
  • Ouhuang Engineering Materials (Hubei) Co., Ltd
  • CALYCOSIN pictures
  • CALYCOSIN
    20575-57-9
  • US $510.00-470.00 / Grams
  • 99.99%
  • Hebei Dangtong Import and export Co LTD
  • CALYCOSIN pictures
  • CALYCOSIN
    20575-57-9
  • US $50.00 / kg
  • 99.9%
  • Henan Bao Enluo International TradeCo.,LTD

CALYCOSIN Spectrum

CALYCOSIN 7,3'-DIHYDROXY-4'-METHOXYISOFLAVONE 3'-HYDROXYFORMONONETIN 3',7-DIHYDROXY-4'-METHOXYISOFLAVONE 3-(3-Hydroxy-4-methoxyphenyl)-7-hydroxy-4H-1-benzopyran-4-one 7-Hydroxy-3-(3-hydroxy-4-methoxyphenyl)-4H-1-benzopyran-4-one Astraisoflavone Clycosin CALYCOSIN(SH) 7-hydroxy-3-(3-hydroxy-4-methoxyphenyl)-4H-chromen-4-one Calycosin 20575-57-9 7-hydroxy-3-(3-hydroxy-4-methoxyphenyl)-1-benzopyran-4-one Calycosin, 98%, from Astragalus membranaceus Bunge Calycosin (Cyclosin) 4H-1-Benzopyran-4-one, 7-hydroxy-3-(3-hydroxy-4-methoxyphenyl)- Calycosin >=98% (HPLC) 3',7-Dihydroxy-4'-methoxy-isoflavone7-hydroxy-3-(3-hydroxy-4-methoxyphenyl)chromen-4-one 7,3'-dihydroxy-4'-methoxyisoflavanon-2-ene 7,5'-dihydroxy-4'-methoxyisoflavone 7-hydroxy-3-(3-hydroxy-4-methoxyphenyl)- 7-Hydroxy-3-(3-hydroxy-4-methoxyphenyl)-4H-chromen-4-one4H-1-Benzopyran-4-one 7-Hydroxy-3-(3-hydroxy-4-methoxyphenyl)-4H-chromen-4-one[Cyclosin] Balofloxacin Impurity 8 20575-57-9 C16H12O5 chemical reagent pharmaceutical intermediate phytochemical reference standards from Chinese medicinal herbs (TCM). standardized herbal extract reference substance Iso-Flavones The group of Astralosides