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DMT-2'O-TBDMS-rA(bz) Phosphoramidite

DMT-2'O-TBDMS-rA(bz) Phosphoramidite structure

CAS No.: 104992-55-4

Chemical Name:: DMT-2'O-TBDMS-rA(bz) Phosphoramidite

Synonyms: Bz-rA Phosphoramidite;2'-TBDMS-A CEP;N-Benzoyl-5-O-(4;RNA N-Bz A Amidite;8-Aza-7-deaza-A CEP;DMT-2'-0-TBDMS-rA(BZ);DMT-2'-O-TBDMS-A(Bz)-CE;2’-OTBDMS-rA(Bz) Amidite;N-diisopropyl)phosphoramidite;2TBDMS-rA(BZ) Phosphoramidite

CBNumber:: CB41871629

Molecular Formula:: C53H66N7O8PSi

Molecular Weight:: 988.19

MDL Number:: MFCD00080297

MOL File:: 104992-55-4.mol

MSDS File:: SDS

Last updated:2025-01-27 09:38:02

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DMT-2'O-TBDMS-rA(bz) Phosphoramidite Properties

storage temp.	Inert atmosphere,Store in freezer, under -20°C
form	powder
pka	7.87±0.43(Predicted)
color	white to off-white
biological source	non-animal source (no BSE/TSE risk)
InChIKey	FFXHNCNNHASXCT-RFMFGJHUSA-N
UNSPSC Code	12352200
NACRES	NA.51

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS07
Signal word	Warning
Hazard statements	H302-H315-H319-H335
Precautionary statements	P261-P280-P301+P312-P302+P352-P305+P351+P338
WGK Germany	3
HS Code	29349990

DMT-2'O-TBDMS-rA(bz) Phosphoramidite price More Price(43)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	A211050	DMT-2′O-TBDMS-rA(bz) Phosphoramidite configured for (?KTA? and OligoPilot?)	104992-55-4	2g	$188	2024-03-01	Buy
Sigma-Aldrich	A211050	DMT-2′O-TBDMS-rA(bz) Phosphoramidite configured for (?KTA? and OligoPilot?)	104992-55-4	10g	$916	2024-03-01	Buy
Sigma-Aldrich	A211040	DMT-2′O-TBDMS-rA(bz) Phosphoramidite configured for MerMade	104992-55-4	5G	$372	2024-03-01	Buy
Sigma-Aldrich	A211040	DMT-2′O-TBDMS-rA(bz) Phosphoramidite configured for MerMade	104992-55-4	10g	$941	2024-03-01	Buy
Sigma-Aldrich	A211000	DMT-2′O-TBDMS-rA(bz) Phosphoramidite	104992-55-4	100g	$7590	2024-03-01	Buy

Product number	Packaging	Price	Buy
A211050	2g	$188	Buy
A211050	10g	$916	Buy
A211040	5G	$372	Buy
A211040	10g	$941	Buy
A211000	100g	$7590	Buy

DMT-2'O-TBDMS-rA(bz) Phosphoramidite Chemical Properties,Uses,Production

Uses

N-Benzoyl-5'-O-(4,4-Dimethoxytrityl)-2'-O-[(tert-butyl)dimethylsilyl]adenosine-3'-(2-cyanoethyl-N,N-diisopropyl)phosphoramidite can be used as Organic synthesis intermediates and pharmaceutical intermediates are mainly used in laboratory research and development processes and chemical production processes.

Uses

DMT-2''O-TBDMS-rA(bz) Phosphoramidite (DMT-2'O-TBDMS-rA(bz) Phosphoramidite) is a 2''-O-Protected ribonucleoside phosphoramidite used as a key raw material for the automated solid-supported synthesis of oligonucleotide-based drugs. It is also used to synthesize 2''-O-guanidinopropyl-modified nucleoside phosphoramidites to incorporate into siRNAs targeting hepatitis B virus.

Synthesis

Synthesis_104992-55-4
To a solution of 72 (12.0 g, 15.2 mmoi) in DIPEA (15 ml) and DCM (30 mL) is added DMAP (744 mg, 6.09 rnrnol) and 2cyanoethyl JV.Ndiisopropylchlorophosphoramidite (5.41 g, 22.9 rnmoi) at 25 ℃. After stirring for 2 hours, the mixture is purified directly by basic silica gel column chromatography (EAIPE 1/4 toi/1) to give DMT-2'O-TBDMS-rA(bz) Phosphoramidite as a white solid (13.0 g. 86% yield)

DMT-2'O-TBDMS-rA(bz) Phosphoramidite Preparation Products And Raw materials

Raw materials

Preparation Products

DMT-2'O-TBDMS-rA(bz) Phosphoramidite Suppliers

Global( 190)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Allbiosyn Biotechnology Co.,Ltd.	+8618666985712	info@allbiosyn.com	China	295	58
Capot Chemical Co.,Ltd.	+86-（0）57185586718 +86-13336195806	sales@capot.com	China	29730	60
Shanghai Daken Advanced Materials Co.,Ltd	+86-2158073036	info@dakenam.com	China	19886	58
Henan Tianfu Chemical Co.,Ltd.	+86-0371-55170693 +86-19937530512	info@tianfuchem.com	China	21626	55
career henan chemical co	+86-0371-86658258 +8613203830695	sales@coreychem.com	China	29856	58
Jinan Carbotang Biotech Co.,Ltd.	+8615866703830	figo.gao@foxmail.com	China	8497	58
Yunbio Tech Co.,Ltd.	+86-010-60605551 +86-18046518538	yunbiochem@126.com	China	321	58
Nanjing Baifuli Technology Co., Ltd.	+86-15335185688	sales@unisyn.cn	CHINA	332	58
BOC Sciences	+1-631-485-4226	inquiry@bocsci.com	United States	19552	58
Alchem Pharmtech,Inc.	8485655694	sales@alchempharmtech.com	United States	63687	58

Supplier	Advantage
Allbiosyn Biotechnology Co.,Ltd.	58
Capot Chemical Co.,Ltd.	60
Shanghai Daken Advanced Materials Co.,Ltd	58
Henan Tianfu Chemical Co.,Ltd.	55
career henan chemical co	58
Jinan Carbotang Biotech Co.,Ltd.	58
Yunbio Tech Co.,Ltd.	58
Nanjing Baifuli Technology Co., Ltd.	58
BOC Sciences	58
Alchem Pharmtech,Inc.	58

View Lastest Price from DMT-2'O-TBDMS-rA(bz) Phosphoramidite manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2025-04-04	Bz-rA Phosphoramidite 104992-55-4	US $0.00-0.00 / kg	1kg	98%	1Ton	Henan Aochuang Chemical Co.,Ltd.
2024-08-08	N6-Bz-5'-O-DMT-2'-O-TBDMS-A-CE 104992-55-4	US $0.00 / mg	100mg	≥98%	20tons	Hefei Huana Biomedical Technology Co.,Ltd.
2023-03-22	2'-O-TBDMS-A(Bz) CE Phosphoramidite;Bz-rA 104992-55-4	US $100.00 / kg	0.009999999776482582kg	99%	5tons	SHANGHAI NOVRIBO BIOTECH

Bz-rA Phosphoramidite
104992-55-4
US $0.00-0.00 / kg
98%
Henan Aochuang Chemical Co.,Ltd.

N6-Bz-5'-O-DMT-2'-O-TBDMS-A-CE
104992-55-4
US $0.00 / mg
≥98%
Hefei Huana Biomedical Technology Co.,Ltd.

2'-O-TBDMS-A(Bz) CE Phosphoramidite;Bz-rA
104992-55-4
US $100.00 / kg
99%
SHANGHAI NOVRIBO BIOTECH

104992-55-4(DMT-2'O-TBDMS-rA(bz) Phosphoramidite)Related Search:

BENZOYL ISOCYANATE Buprofezin ADENOSINE 5'-TRIPHOSPHATASE tert-Butanol Benzoyl chloride

Cyhalofop-butyl Benzoyl peroxide Dimethyldimethoxysilane tert-Butyl acetate tert-Butyldimethylsilyl chloride

tert-Butyl peroxyacetate N-Benzoylaminopurine 5'-O-(4,4'-DIMETHOXYTRITYL)-2'-DEOXYADENOSINE TERT-BUTYLDIMETHYLSILANOL N6-Benzoyl-5'-O-(4,4'-dimethoxytrityl)-2'-deoxyadenosine

N6-BENZYLADENOSINE N6-BENZOYL-3'-DEOXYADENOSINE DIMETHYL N,N-DIISOPROPYLPHOSPHORAMIDITE

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DMT-2′O-TBDMS-rA(bz) Phosphoramidite 2'-TBDMS -Bz-rA-CE-Phosphoramidite 5'-DMT-2'-O-TBDMS- N6-Benzoyl-Adenosine Phosphoramidite (2R,3R,4R,5R)-5-(6-benzamido-9H-purin-9-yl)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-(tert-butyldimethylsilyloxy)tetrahydrofuran-3-yl 2-cyanoethyl diisopropylphosphoramidite REF DUPL: 2'-TBDMS-rA(N-Bz)Phosphoramidite N6-Benzoyl-2'-O-tert-butyldimethylsilyl-5'-O-DMT-adenosine 3'-CE phosphoramidite 5'-O-(4,4'-DiMethoxy)-N6-benzoyl-2'-O-(t-butyl diMethylsilyl)adenosine-3'-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoraMidite 5'-O-DMT-2'-O-TDMS-N6-Bz-Adenosine-3'-CED PhosphoraMidite Adenosine, N-benzoyl-5'-O-[bis(4-Methoxyphenyl)phenylMethyl]-2'-O-[(1,1-diMethylethyl)diMethylsilyl]-, 3'-[2-cyanoethyl bis(1-Methylethyl)phosphoraMidite] 2’-TBDMS-rA(N-Bz) Phosphoramidite 5'-O-DMT-2'-TBDMS-rA(N-Bz)-3'-CEDPA N-Benzoyl-5'-O-(4,4-Dimethoxytrityl)-2'-O-[(tert-butyl)dimethylsilyl]adenosine-3'-(2-cyanoethyl-N,N-diisopropyl)phosphoramidite Adenosine, N-benzoyl-5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-O-[(1,1-dimethylethyl)dimethylsilyl]-, 3'-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite] N-[9-[(2R,3R,4R,5R)-5-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-3-[tert-butyl(dimethyl)silyl]oxy-4-[2-cyanoethoxy-[di(propan-2-yl)amino]phosphanyl]oxyoxolan-2-yl]purin-6-yl]benzamide 5'-DMT-2'-TBDMS-rA(N-Bz) Phosphoramidite N6-Benzoyl-5'-O-(4, 4'-dimethoxytrityl)-2'-O-(tert-butyldimethylsilyl)adenosine-3'-(2-cyanoethyl-N,N-diisopropyl)phosphoramidite TIANFU-CHEM N-Benzoyl-5'-O-(4,4-Dimethoxytrityl)-2'-O-[(tert-butyl)dimethylsilyl]adenosine-3'-(2-cyanoethyl-N,N-diisopropyl)phosphoramidite 5'-Dimethoxytrityl-N-benzoyl-Adenosine, 2'-O-TBDMS-3'-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite N-Benzoyl-5'-O-(4,4-Dimethoxytrityl)-2'-O-[(tert-butyl)dimet... N-diisopropyl)phosphoramidite N-Benzoyl-5-O-(4 4-Dimethoxytrityl)-2-O-[(tert-butyl)dimethylsilyl]adenosine-3-(2-cyanoethyl-N 5'-DMT-2'-TBDMS-N6-Bz-rA phosphoramidite 2'-TBDMS-A CEP 5'-O-DMT-2'-O-TBDMS-N6-Benzoyl-Adenosine 3'-CE phosphoramidite 5'-O-DMT-2'-O-tert-Butyldimethylsilyl-N6-Benzoyl-adenosine 3'-CE phosphoramidite Adenosine,N-benzoyl-5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-O-[(1,1-dimethylethyl)dimethylsilyl]-,3'-[2-cyanoethyl bis(1-methylethyl)phosphoramidite] (9CI) 8-Aza-7-deaza-A CEP 5'-O-DMT-2'-O-tert-Butyldimethylsiyl-N6-Benzoyl-adenosine 3'-CE phosphoramidite Bz-rA Phosphoramidite N6-Benzoyl-5'-O-DMT-2'-O-TBDMS adenosine 3'-CE phosphoramidite 2TBDMS-rA(BZ) Phosphoramidite N6-Bz-5'-O-DMT-2'-O-TBDMS-A-CE 2'-O-TBDMS-A(Bz) CE Phosphoramidite 5'-O-DMT-2'-O-TBDMS-N6-Benzoyl-Adenosine-3’-Cyanoethyl Phosphoramidite RNA N-Bz A Amidite DMT-2'-O-TBDMS-A(Bz)-CE DMTr-2'-O-TBDMS-rA(Bz)-3'-CE-Phosphoramidite 2’-OTBDMS-rA(Bz) Amidite 5'-ODMT-2'-OTBDMS-N-Bz Adenosine-3'-OCEPA DMT-2'-0-TBDMS-rA(BZ) DMT-2'O-TBDMS-rA(bz) Phosphoramidite 2'-O-TBDMS-A(Bz)-CE Phosphoramidite DMT-2'-O-TBDMS-A(Bz)-CE-Phosphoramidite N6-benzoyl-5'-O-(4,4'-dimethoxytrityl)-2'-O-(tert-butyldimethylsilyl)adenosine 3'-O-(2-cyanoethyl N,N-diisopropylphosphoramidite) N-(9-[(2R,4R,5R)-5-[(bis(4-methoxyphenyl)(phenyl)methoxy)methyl]-4-{[(bis(propan-2-yl)amino)(2-cyanoethoxy)phosphanyl]oxy}-3-[(tert-butyldimethylsilyl)oxy]oxolan-2-yl]-9H-purin-6-yl)benzamide N6-Bz-2'-O-TBDMS-5'-O-DMT-A-3'-CE-Phosphoramidite 2'-TBDMS-rA(Bz)Phosphoramidite Adenosine, N-benzoyl-5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-O-[(1,1-dimethylethyl)dimethylsilyl]-, 3'-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite 5'-O-DMT-2'-O-tert-Butyldimethylsiyl-N6-Benzoyl-adenosine 3'-CE phosphoramidite DMT-2'-0-TBDMS-A(Bz)-CE-Phosphoramidite 104992-55-4 C53H66N7O8PSi Pharmaceutical Amidite