ChemicalBook >> CAS DataBase List >>2H-Pyrrol-2-one, 4-acetyl-1-(4-chloro-2-fluorophenyl)-5-cyclohexyl-1,5-dihydro-3-hydroxy-, (5R)-

2H-Pyrrol-2-one, 4-acetyl-1-(4-chloro-2-fluorophenyl)-5-cyclohexyl-1,5-dihydro-3-hydroxy-, (5R)-

2H-Pyrrol-2-one, 4-acetyl-1-(4-chloro-2-fluorophenyl)-5-cyclohexyl-1,5-dihydro-3-hydroxy-, (5R)- structure

CAS No.: 512177-83-2

Chemical Name:: 2H-Pyrrol-2-one, 4-acetyl-1-(4-chloro-2-fluorophenyl)-5-cyclohexyl-1,5-dihydro-3-hydroxy-, (5R)-

Synonyms: 187305;4-ACETYL-1-(4-CHLORO-2-FLUOROPHENYL)-5-CYCLOHEXYL-3-HYDROXY-5H-PYRROL-2-ONE;CCR,Inhibitor,inhibit,CCR-2-RA-[R],CC chemokine receptor,CCR2RA[R],CCR2 RA [R;(R)-4-Acetyl-1-(4-chloro-2-fluorophenyl)-5-cyclohexyl-3-hydroxy-1H-pyrrol-2(5H)-one;(R)-4-acetyl-1-(4-chloro-2-fluorophenyl)-5-cyclohexyl-3-hydroxy-1,5-dihydro-2H-pyrrol-2-one;(5R)-4-Acetyl-1-(4-chloro-2-fluorophenyl)-5-cyclohexyl-1,5-dihydro-3-hydroxy-2H-pyrrol-2-one;2H-Pyrrol-2-one, 4-acetyl-1-(4-chloro-2-fluorophenyl)-5-cyclohexyl-1,5-dihydro-3-hydroxy-, (5R)-

CBNumber:: CB41871836

Molecular Formula:: C18H19ClFNO3

Molecular Weight:: 351.8

MDL Number:

MOL File:: 512177-83-2.mol

Last updated:2024-07-02 08:55:08

Request For Quotation

2H-Pyrrol-2-one, 4-acetyl-1-(4-chloro-2-fluorophenyl)-5-cyclohexyl-1,5-dihydro-3-hydroxy-, (5R)- Properties

Boiling point	482.6±45.0 °C(Predicted)
Density	1.383±0.06 g/cm3(Predicted)
storage temp.	Store at -20°C
solubility	DMF: 30 mg/ml; DMSO: 30 mg/ml; DMSO:PBS (pH 7.2) (1:3): 0.25 mg/ml; Ethanol: 1 mg/ml
form	A crystalline solid
pka	4.50±1.00(Predicted)
color	White to off-white

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS07

Signal word

Warning

Hazard statements

H315-H319-H335

Precautionary statements

P261-P264-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P321-P362+P364-P332+P313-P337+P313-P403+P233-P405-P501

NFPA 704

	0
2		0

2H-Pyrrol-2-one, 4-acetyl-1-(4-chloro-2-fluorophenyl)-5-cyclohexyl-1,5-dihydro-3-hydroxy-, (5R)- price More Price(14)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Cayman Chemical	28423	CCR2-RA-[R]	512177-83-2	1mg	$50	2024-03-01	Buy
Cayman Chemical	28423	CCR2-RA-[R]	512177-83-2	25mg	$606	2024-03-01	Buy
Cayman Chemical	28423	CCR2-RA-[R]	512177-83-2	5mg	$172	2024-03-01	Buy
Cayman Chemical	28423	CCR2-RA-[R]	512177-83-2	10mg	$292	2024-03-01	Buy
TRC	A179105	(5R)-4-Acetyl-1-(4-chloro-2-fluorophenyl)-5-cyclohexyl-1,5-dihydro-3-hydroxy-2H-pyrrol-2-one	512177-83-2	5mg	$165	2021-12-16	Buy

Product number	Packaging	Price	Buy
28423	1mg	$50	Buy
28423	25mg	$606	Buy
28423	5mg	$172	Buy
28423	10mg	$292	Buy
A179105	5mg	$165	Buy

2H-Pyrrol-2-one, 4-acetyl-1-(4-chloro-2-fluorophenyl)-5-cyclohexyl-1,5-dihydro-3-hydroxy-, (5R)- Chemical Properties,Uses,Production

Uses

(5R)-4-Acetyl-1-(4-chloro-2-fluorophenyl)-5-cyclohexyl-1,5-dihydro-3-hydroxy-2H-pyrrol-2-one, is an allosteric antagonist of the C-C chemokine receptor type 2 (CCR2) with an IC50 of 103 nM.

2H-Pyrrol-2-one, 4-acetyl-1-(4-chloro-2-fluorophenyl)-5-cyclohexyl-1,5-dihydro-3-hydroxy-, (5R)- Preparation Products And Raw materials

Raw materials

Preparation Products

2H-Pyrrol-2-one, 4-acetyl-1-(4-chloro-2-fluorophenyl)-5-cyclohexyl-1,5-dihydro-3-hydroxy-, (5R)- Suppliers

Global( 33)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
TargetMol Chemicals Inc.	+1-781-999-5354 +1-00000000000	marketing@targetmol.com	United States	19892	58
Career Henan Chemica Co	+86-0371-86658258 +8613203830695	laboratory@coreychem.com	China	30250	58
ShenZhen Trendseen Biological Technology Co.,Ltd.	13417589054	trendseenbio@gmail.com	China	11681	58
Shenyang Zhongshen Zekang Biomedical Technology Research Co., Ltd	+86-18341751992 +86-15382112998	757984502@qq.com	China	892	58
Aladdin Scientific	+1-+1(833)-552-7181	sales@aladdinsci.com	United States	52927	58
ChemShuttle, Inc.	0510-83588313-802 18800520310;	sales@chemshuttle.com	China	2996	62
Shanghai EFE Biological Technology Co., Ltd.	021-65675885 18964387627	info@efebio.com	China	9707	58
Shanghai Chaolan Chemical Technology Center	QQ:65489617 15618227136	info@SuperLan-chem.com	China	9943	58
Beijing Solarbio Science & Tecnology Co., Ltd.	010-50973130 4009686088	3193328036@qq.com	China	29786	68
Dezhou LonWel Pharmaceutical Technology Co., Ltd.	13761310616	39324283@qq.com	China	1989	58

Supplier	Advantage
TargetMol Chemicals Inc.	58
Career Henan Chemica Co	58
ShenZhen Trendseen Biological Technology Co.,Ltd.	58
Shenyang Zhongshen Zekang Biomedical Technology Research Co., Ltd	58
Aladdin Scientific	58
ChemShuttle, Inc.	62
Shanghai EFE Biological Technology Co., Ltd.	58
Shanghai Chaolan Chemical Technology Center	58
Beijing Solarbio Science & Tecnology Co., Ltd.	68
Dezhou LonWel Pharmaceutical Technology Co., Ltd.	58

2H-Pyrrol-2-one, 4-acetyl-1-(4-chloro-2-fluorophenyl)-5-cyclohexyl-1,5-dihydro-3-hydroxy-, (5R)- Spectrum

2H-Pyrrol-2-one, 4-acetyl-1-(4-chloro-2-fluorophenyl)-5-cyclohexyl-1,5-dihydro-3-hydroxy-, (5R)-(512177-83-2)¹HNMR

512177-83-2(2H-Pyrrol-2-one, 4-acetyl-1-(4-chloro-2-fluorophenyl)-5-cyclohexyl-1,5-dihydro-3-hydroxy-, (5R)-)Related Search:

Cyfluthrin

2H-Pyrrol-2-one, 4-acetyl-1-(4-chloro-2-fluorophenyl)-5-cyclohexyl-1,5-dihydro-3-hydroxy-, (5R)- (R)-4-acetyl-1-(4-chloro-2-fluorophenyl)-5-cyclohexyl-3-hydroxy-1,5-dihydro-2H-pyrrol-2-one 187305 (R)-4-Acetyl-1-(4-chloro-2-fluorophenyl)-5-cyclohexyl-3-hydroxy-1H-pyrrol-2(5H)-one (5R)-4-Acetyl-1-(4-chloro-2-fluorophenyl)-5-cyclohexyl-1,5-dihydro-3-hydroxy-2H-pyrrol-2-one CCR,Inhibitor,inhibit,CCR-2-RA-[R],CC chemokine receptor,CCR2RA[R],CCR2 RA [R 4-ACETYL-1-(4-CHLORO-2-FLUOROPHENYL)-5-CYCLOHEXYL-3-HYDROXY-5H-PYRROL-2-ONE 512177-83-2 C18H19ClFNO3