Sodium 3-nitrobenzenesulphonate
- CAS No.
- 127-68-4
- Chemical Name:
- Sodium 3-nitrobenzenesulphonate
- Synonyms
- RESIST SALT;SODIUM 3-NITROBENZENESULFONATE;3-NITROBENZENESULFONIC ACID SODIUM SALT;ludigol;3-Nitrobenzenesulfonate;3-nitrobenzenesulphonate;tiskan;SODIUM M-NITROBENZENESULFONATE;SMNBS;Ludigo
- CBNumber:
- CB4193939
- Molecular Formula:
- C6H4NNaO5S
- Molecular Weight:
- 225.15
- MDL Number:
- MFCD00007490
- MOL File:
- 127-68-4.mol
- MSDS File:
- SDS
| Product description | Number | Pack Size | Price |
| 3-Nitrobenzenesulfonic acid sodium salt for synthesis | 8.06548 | 100g | $29.3 |
| 3-Nitrobenzenesulfonic acid sodium salt for synthesis | 8.06548 | 1kg | $80.9 |
| Sodium 3-nitrobenzenesulfonate 98% | 225193 | 100g | $48.2 |
| Sodium 3-nitrobenzenesulfonate 98% | 225193 | 500g | $74.4 |
| Sodium 3-Nitrobenzenesulfonate >95.0%(T) | N0141 | 25g | $19 |
| More product size | |||
| Melting point | 350 °C |
|---|---|
| Boiling point | 217.5°C |
| Density | 0.45 g/cm3 (20 °C) |
| bulk density | 450kg/m3 |
| vapor pressure | 10.3Pa at 25℃ |
| Flash point | 100 °C |
| storage temp. | Store below +30°C. |
| solubility | water: soluble50mg/mL, clear to slightly hazy, faintly yellow to yellow |
| pka | 0[at 20 ℃] |
| form | Crystalline Powder |
| color | Light yellow |
| PH | 8 (50g/l, H2O, 23℃) |
| Water Solubility | 200 g/L (20 ºC) |
| Sensitive | Hygroscopic |
| BRN | 3639982 |
| Stability | Stable. Hygroscopic. Incompatible with strong oxidizing agents. |
| Cosmetics Ingredients Functions | VISCOSITY CONTROLLING |
| InChIKey | LJRGBERXYNQPJI-UHFFFAOYSA-M |
| LogP | -2.61 at 25℃ |
| CAS DataBase Reference | 127-68-4(CAS DataBase Reference) |
| EWG's Food Scores | 2-3 |
| FDA UNII | 1F11SXJ4C6 |
| EPA Substance Registry System | Sodium 3-Nitrobenzenesulfonate (127-68-4) |
| UNSPSC Code | 12352107 |
| NACRES | NA.22 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H317-H319 | |||||||||
| Precautionary statements | P280-P302+P352-P305+P351+P338 | |||||||||
| Hazard Codes | Xi | |||||||||
| Risk Statements | 36-43 | |||||||||
| Safety Statements | 24-26-37 | |||||||||
| WGK Germany | 1 | |||||||||
| RTECS | DB7195000 | |||||||||
| Autoignition Temperature | 355 °C | |||||||||
| TSCA | Yes | |||||||||
| HS Code | 29049085 | |||||||||
| Hazardous Substances Data | 127-68-4(Hazardous Substances Data) | |||||||||
| Toxicity | LD50 orally in Rabbit: > 2000 mg/kg | |||||||||
| NFPA 704 |
|
Sodium 3-nitrobenzenesulphonate price More Price(30)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 8.06548 | 3-Nitrobenzenesulfonic acid sodium salt for synthesis | 127-68-4 | 100g | $29.3 | 2025-07-31 | Buy |
| Sigma-Aldrich | 8.06548 | 3-Nitrobenzenesulfonic acid sodium salt for synthesis | 127-68-4 | 1kg | $80.9 | 2025-07-31 | Buy |
| Sigma-Aldrich | 225193 | Sodium 3-nitrobenzenesulfonate 98% | 127-68-4 | 100g | $48.2 | 2025-07-31 | Buy |
| Sigma-Aldrich | 225193 | Sodium 3-nitrobenzenesulfonate 98% | 127-68-4 | 500g | $74.4 | 2025-07-31 | Buy |
| TCI Chemical | N0141 | Sodium 3-Nitrobenzenesulfonate >95.0%(T) | 127-68-4 | 25g | $19 | 2025-07-31 | Buy |
Sodium 3-nitrobenzenesulphonate Chemical Properties,Uses,Production
Chemical Properties
solid
Uses
Sodium 3-nitrobenzenesulfonate is a reagent in the synthesis of azetidinyl ketolides for treatment of susceptible and multidrug resistant community-acquired respiratory tract infections.
Flammability and Explosibility
Non flammable
Synthesis
98-95-3
127-68-4
1) In a 500 mL four-neck flask equipped with a thermometer, mechanical stirrer and exhaust gas absorption device, 246 g (2.0 mol) of nitrobenzene and 139 g (1.2 mol) of chlorosulfonic acid were added. Stirring was initiated and heated to 120 °C, and the sulfonation reaction was maintained at this temperature for 3 hours. The hydrogen chloride gas generated during the reaction was introduced into 200 mL of deionized water through the tail gas absorption device, and finally an aqueous hydrogen chloride solution with a mass concentration of 17.5% was obtained. (2) After the reaction was completed, the reaction mixture was cooled to room temperature, 500 mL of water and 63.6 g (0.6 mol) of sodium carbonate were added and stirred thoroughly. The oil layer was separated after standing. The oil layer was washed three times with 500 mL of water and subsequently dried over 35 g of molecular sieves to give 95 g of recovered nitrobenzene with 99.3% purity. The aqueous layer solution was dried by a spray drying unit (feed rate 15-20 mL/min, inlet temperature 300 °C, outlet temperature 100 °C) to give 266 g of dried sodium nitrobenzenesulfonate product with 99.0% purity and 98.4% yield (in terms of consumed nitrobenzene).
References
[1] Patent: CN108997175, 2018, A. Location in patent: Paragraph 0046-0059; 0062-0066
Sodium 3-nitrobenzenesulphonate Preparation Products And Raw materials
Raw materials
1of2
Preparation Products
1of2
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Wuhan Pinestone Fortune International Trading Co., Ltd. | +86-027-85615902 +86-13971435335 | imp.exp8@fengfan.net | China | 29 | 58 |
| ZHEJIANG XINHAITIAN BIOLOGICAL TECHNOLOGY CO.,LTD. | 0086-15925805416 | elaine.xu@sxhtzj.com | China | 22 | 58 |
| Hebei Chuanghai Biotechnology Co., Ltd | +8615350571055 | Sibel@chuanghaibio.com | China | 8767 | 58 |
| Hebei Chuanghai Biotechnology Co,.LTD | +86-13131129325 | sales1@chuanghaibio.com | China | 5249 | 58 |
| Wuhan Kemi-Works Chemical Co., Ltd. | +86-2785736489 +8618171418573 | sales@kemiworks.com | China | 782 | 58 |
| Hebei Zhuanglai Chemical Trading Co.,Ltd | +8613343047651 | admin@zlchemi.com | China | 3692 | 58 |
| Capot Chemical Co.,Ltd. | +86-（0）57185586718; +8613336195806 | sales@capot.com | China | 29735 | 60 |
| Shanghai Daken Advanced Materials Co.,Ltd | +86-2158073036 | info@dakenam.com | China | 13595 | 58 |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21610 | 55 |
| Shanghai Time Chemicals CO., Ltd. | +86-021-57951555 +8617317452075 | jack.li@time-chemicals.com | China | 1803 | 55 |
View Lastest Price from Sodium 3-nitrobenzenesulphonate manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2025-12-17 | Sodium 3-nitrobenzenesulphonate
127-68-4
|
US $1.00 / kg | 1kg | ≥99% | 1000mt/year | Jinan Finer Chemical Co., Ltd | |
 |
2025-12-15 | Sodium 3-nitrobenzenesulphonate
127-68-4
|
0.99 | RongNa Biotechnology Co.,Ltd | ||||
 |
2025-12-11 | Sodium 3-nitrobenzenesulphonate
127-68-4
|
US $10.00 / KG | 1KG | 99% | 10 mt | Hebei Chuanghai Biotechnology Co., Ltd |
-
- Sodium 3-nitrobenzenesulphonate
127-68-4
- US $1.00 / kg
- ≥99%
- Jinan Finer Chemical Co., Ltd
-
- Sodium 3-nitrobenzenesulphonate
127-68-4
- 0.99
- RongNa Biotechnology Co.,Ltd
-
- Sodium 3-nitrobenzenesulphonate
127-68-4
- US $10.00 / KG
- 99%
- Hebei Chuanghai Biotechnology Co., Ltd
