ChemicalBook >> CAS DataBase List >>Chlorfenapyr

Chlorfenapyr

Chlorfenapyr structure

CAS No.: 122453-73-0

Chemical Name:: Chlorfenapyr

Synonyms: 4-BROMO-2-(4-CHLOROPHENYL)-1-(ETHOXYMETHYL)-5-(TRIFLUOROMETHYL)-1H-PYRROL-3-CARBONITRILE;Alert;PIRATE;STALKER;Intrepid;Pylon;Citrex;Kotersu;Sunfire;Kotetsu

CBNumber:: CB4221357

Molecular Formula:: C15H11BrClF3N2O

Molecular Weight:: 407.61

MDL Number:: MFCD01631152

MOL File:: 122453-73-0.mol

MSDS File:: SDS

TDS File:: TDS

Last updated:2026-07-31 15:25:14

Product description	Number	Pack Size	Price
Chlorfenapyr PESTANAL?, analytical standard	37913	100mg	$98.1
Chlorfenapyr PESTANAL	37913	100mg-r	$70.2
Chlorfenapyr	C3653	5G	$82
Chlorfenapyr	C3653	25G	$285
Chlorfenapyr ≥98%	24141	50mg	$36
More product size

Request For Quotation

Chlorfenapyr Properties

Melting point	91-92°
Boiling point	443.5±45.0 °C(Predicted)
Density	1.53±0.1 g/cm3(Predicted)
storage temp.	Sealed in dry,2-8°C
Water Solubility	Insoluble in water
solubility	DMSO: 250 mg/mL (613.33 mM)
pka	-18.00±0.70(Predicted)
form	Solid
color	White to Almost white
BRN	6940152
Henry's Law Constant	1.7×10³ mol/(m³Pa) at 25℃, HSDB (2015)
Major Application	agriculture environmental
InChI	InChI=1S/C15H11BrClF3N2O/c1-2-23-8-22-13(9-3-5-10(17)6-4-9)11(7-21)12(16)14(22)15(18,19)20/h3-6H,2,8H2,1H3
InChIKey	CWFOCCVIPCEQCK-UHFFFAOYSA-N
SMILES	N1(COCC)C(C(F)(F)F)=C(Br)C(C#N)=C1C1=CC=C(Cl)C=C1
CAS DataBase Reference	122453-73-0(CAS DataBase Reference)
EWG's Food Scores	1
FDA UNII	NWI20P05EB
NIST Chemistry Reference	Chlorfenapyr(122453-73-0)
Pesticides Freedom of Information Act (FOIA)	Chlorfenapyr
EPA Substance Registry System	Chlorfenapyr (122453-73-0)
UNSPSC Code	41116107
NACRES	NA.24

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS06,GHS09

Signal word

Danger

Hazard statements

H302-H331-H410

Precautionary statements

P261-P264-P270-P273-P301+P312-P304+P340+P311

PPE

Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges

Hazard Codes

T;N,N,T

Risk Statements

22-23-50/53

Safety Statements

13-36/37-45-60-61

RIDADR

UN 2811

WGK Germany

HS Code

2933.99.1701

Storage Class

6.1C - Combustible acute toxic Cat.3
toxic compounds or compounds which causing chronic effects

Hazard Classifications

Acute Tox. 3 Inhalation
Acute Tox. 4 Oral
Aquatic Acute 1
Aquatic Chronic 1

Hazardous Substances Data

122453-73-0(Hazardous Substances Data)

Toxicity

LD50 (single dose) in male, female rats (mg/kg): 223, 459 orally; in rabbits: >2000 dermally (Lovell); LC50 in Japanese carp: 0.5 ppm (Lovell)

NFPA 704

	0
4		0

Chlorfenapyr price More Price(61)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	37913	Chlorfenapyr PESTANAL?, analytical standard	122453-73-0	100mg	$98.1	2026-04-30	Buy
Sigma-Aldrich	37913	Chlorfenapyr PESTANAL	122453-73-0	100mg-r	$70.2	2021-12-16	Buy
TCI Chemical	C3653	Chlorfenapyr	122453-73-0	5G	$82	2026-04-30	Buy
TCI Chemical	C3653	Chlorfenapyr	122453-73-0	25G	$285	2026-04-30	Buy
Cayman Chemical	24141	Chlorfenapyr ≥98%	122453-73-0	50mg	$36	2026-04-30	Buy

Product number	Packaging	Price	Buy
37913	100mg	$98.1	Buy
37913	100mg-r	$70.2	Buy
C3653	5G	$82	Buy
C3653	25G	$285	Buy
24141	50mg	$36	Buy

Chlorfenapyr Chemical Properties,Uses,Production

Description

Chlorfenapyr is a broad spectrum pesticide which is not approved for use in the EU, and only approved for limited applications in the US (applications for ornamental plants in greenhouses). It was originally rejected for FDA approval due to avian and aquatic toxicity. Data on human toxicity is still scarce, but it has moderate mammalian toxicity when taken orally, causing vacuolation of the nervous system in mice and rats. It is not persistent in ecosystems, and has low aqueous solubility.
Chlorfenapyr can also be used as an insect-proofing agent in wool, and has been investigated for applications in malaria control.

Reference

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3039634/
https://www3.epa.gov/pesticides/chem_search/reg_actions/registration/fs_PC-129093_01-Jan-01.pdf
https://sitem.herts.ac.uk/aeru/ppdb/en/Reports/136.htm
https://en.wikipedia.org/wiki/Chlorfenapyr
https://www.pwrc.usgs.gov/resshow/Albers/albers1.htm

Description

Chlorfenapyr is a pyrrole pro-insecticide that is metabolized in vivo into CL 303268 by mixed function oxidases. Chlorfenapyr increases respiratory activity in German cockroaches when used at concentrations ranging from 1 to 10 μg per insect but has no effect on respiration in Sf9 cells when used at concentrations ranging from 1 to 100 μM and does not affect respiration in isolated rat liver mitochondria up to a concentration of 10 μM. Chlorfenapyr is active against a variety of insects including those susceptible and resistant to pyrethroid and organophosphate insecticides, including horn flies (H. irritans) as well as A. culicifacies and A. stephensi mosquitos that carry malaria (LC₅₀s = 2-2.39% suspension impregnated on paper). Chlorfenapyr is lethal to rats with LD₅₀ values of 441 and 1,152 mg/kg for male and female rats, respectively. Formulations containing chlorfenapyr have been used to control termites and in agriculture to control various insects.

Chemical Properties

Off-White Solid

Uses

Chlorfenapyr is a halogenated pyrrole based pro-insecticide. Chlorfenapyr functions by metabolizing into an active insecticide after entering the host. Chlorfenapyr is used primarily as a means of pes t control on cotton.

Uses

Insecticide. Acaricide.

Definition

ChEBI: Chlorfenapyr is a member of the class of pyrroles that is 4-bromo-1H-pyrrole-3-carbonitrile which is substituted at positions 1, 2 and 5 by ethoxymethyl, p-chlorophenyl and trifluoromethyl groups, respectively. A proinsecticide used for termite control and crop protection against several insects and mite pests. It has a role as a proinsecticide and a proacaricide. It is an organofluorine acaricide, an organochlorine acaricide, an organochlorine insecticide, an organofluorine insecticide, a member of monochlorobenzenes, a nitrile, a member of pyrroles and a hemiaminal ether. It is functionally related to a tralopyril.

Production Methods

Chlorfenapyr is produced commercially through a multi-step synthesis that centres on the creation of its key intermediate: 2-(4-chlorophenyl)-1-methyl-5-(trifluoromethyl)-1H-pyrrole-3-carbonitrile. This compound is synthesised via a series of reactions involving halogenated aromatic precursors and pyrrole derivatives. Once the intermediate is obtained, it undergoes etherification with ethyl chloroacetate to form the final active ingredient, 4-bromo-2-(4-chlorophenyl)-1-(ethoxymethyl)-5-(trifluoromethyl)-1H-pyrrole-3-carbonitrile.

Hazard

A poison by ingestion. Moderately toxic by inhalation.

Agricultural Uses

Acaracide, Insecticide, Miticide: Severely Restricted for use in EU. Active in U.S. as a foliar spray in greenhouses for ornamental crops and target pests including mites, caterpillar pests, thrips, and fungus gnats. No food use in U.S. Used on ornamental crops in commercial greenhouses to control mites, caterpillar pests, thrips and fungus gnats. Not for food use. Not an approved substance in EU countries. Registered for use in the U.S.

Trade name

AC 303630®; CL 303630®; PHANTOM®; PIRATE® 3 F; PYLON®; SUMILARV® chlorfenapyr Chemical class: Pyrrole (Pyrazole); Organofluorine

Mechanism of action

Limited systemic activity, mainly stomach but some contact action. Uncoupler of oxidative phosphorylation.

References

[1] BLACK B.C. Insecticidal Action and Mitochondrial Uncoupling Activity of AC-303,630 and Related Halogenated Pyrroles[J]. Pesticide Biochemistry and Physiology, 1994, 50 2: Pages 115-128. DOI: 10.1006/pest.1994.1064
[2] C. SHEPPARD J A J. Increased Susceptibility of Pyrethroid-Resistant Horn Flies (Diptera: Muscidae) to Chlorfenapyr[J]. Journal of Economic Entomology, 1998, 91 1: 398-400. DOI: 10.1093/jee/91.2.398
[3] KAMARAJU RAGHAVENDRA. Chlorfenapyr: a new insecticide with novel mode of action can control pyrethroid resistant malaria vectors.[J]. ACS Applied Bio Materials, 2011: 16. DOI: 10.1186/1475-2875-10-16

Pesticide Type

Insecticide; Acaricide; Miticide

Chlorfenapyr Preparation Products And Raw materials

Raw materials

2-(4-chlorophenyl)-1-methyl-5-(trifluoromethyl)-1H-pyrrole-3-carbonitrile 2-N-BUTOXYETHYL METHACRYLATE Lithium tert-butoxide 2-(4-chlorop henyl)-4，5-dihydro-1-methyl-5-(trifluoromethyl)-1H-pyr role-3-carbonitrile Hexane

4-Chlorobenzaldehyde 4-CHLORO-ALPHA-(METHYLAMINO)BENZENE ACETIC ACID 4-CHLORO-ALPHA-[METHYL(TRIFLUOROACETYL)AMINO]-BENZENEACETIC ACID Anhydrous toluene Trifluoroacetic anhydride

Acrylonitrile

1of3

Preparation Products

Chlorfenapyr Suppliers

Global( 351)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
AS WATER CO., LTD.	+86-18994963526	1346073549@qq.com	United Kingdom	176	58
Qingdao Trust Agri Chemical Co.,Ltd	+86-008615963231493 +86-008613573296305	trustagri@hotmail.com	China	298	58
Hebei Chuanghai Biotechnology Co,.LTD	+86-86-13131129325	sales1@chuanghaibio.com	China	5218	58
Hebei Chuanghai Biotechnology Co., Ltd	+86-17732866630	mina@chuanghaibio.com	China	18114	58
Henan Bao Enluo International TradeCo.，LTD	+86-17331933971	deasea125996@gmail.com	China	2452	58
Henan Tianfu Chemical Co.,Ltd.	+86-0371-55170693 +86-19937530512	info@tianfuchem.com	China	21531	55
career henan chemical co	+86-0371-86658258	sales@coreychem.com	China	29766	58
Shandong chuangyingchemical Co., Ltd.	18853181302	sale@chuangyingchem.com	CHINA	5898	58
Alchem Pharmtech,Inc.	8485655694	sales@alchempharmtech.com	United States	63645	58
CONIER CHEM AND PHARMA LIMITED		sales@conier.com	China	49906	58

Supplier	Advantage
AS WATER CO., LTD.	58
Qingdao Trust Agri Chemical Co.,Ltd	58
Hebei Chuanghai Biotechnology Co,.LTD	58
Hebei Chuanghai Biotechnology Co., Ltd	58
Henan Bao Enluo International TradeCo.，LTD	58
Henan Tianfu Chemical Co.,Ltd.	55
career henan chemical co	58
Shandong chuangyingchemical Co., Ltd.	58
Alchem Pharmtech,Inc.	58
CONIER CHEM AND PHARMA LIMITED	58

View Lastest Price from Chlorfenapyr manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2026-07-14	Chlorfenapyr 122453-73-0		1kg	98	1	Qingdao Trust Agri Chemical Co.,Ltd
2026-06-02	Chlorfenapyr 122453-73-0	$30.00-40.00		99.49%	10g	TargetMol Chemicals Inc.
2026-05-28	Chlorfenapyr 122453-73-0	$5.60	1KG	98%	5000kg	Hebei Chuanghai Biotechnology Co,.LTD

Chlorfenapyr
122453-73-0
$0.00
98
Qingdao Trust Agri Chemical Co.,Ltd

Chlorfenapyr
122453-73-0
$30.00-40.00
99.49%
TargetMol Chemicals Inc.

Chlorfenapyr
122453-73-0
$5.60
98%
Hebei Chuanghai Biotechnology Co,.LTD

Chlorfenapyr Spectrum

Chlorfenapyr(122453-73-0)¹HNMR

122453-73-0(Chlorfenapyr)Related Search:

Ethoxymethylenemalononitrile Fipronil DBDCB 2-Ethoxyphenol Ethoxyquin

Diethoxymethyl acetate DIETHOXYMETHANE 2-(4-CHLOROPHENYL)-4-BROMO-1-METHYL-5-(TRIFLUOROMETHYL)-1H-PYRROLE-3-CARBONITRILE Bromine Pyrrole

2-(4-chlorophenyl)-1-methyl-5-(trifluoromethyl)-1H-pyrrole-3-carbonitrile 1H-Pyrrole-3-carbonitrile,1,2,5-trimethyl-(9CI) 1H-PYRROLE, 3-BROMO-1-METHYL- Chlorfenapyr CHLORFENAPYR SOLUTION 100UG/ML IN ACETONITRILE 1ML

CHLORFENAPYR SOLUTION 100UG/ML IN TOLUENE 1ML Chlorfenapyr10%Ec bromo-Dragonfly

1of4

4-bromo-2-(4-chlorophenyl)-1-ethoxymethyl-5-trifluoromethyl-1H-pyrrole-3-carbonitrile 4-bromo-2-(4-chlorophenyl)-1-ethoxymethyl-5-trifluoromethylpyrrole-3-carbonitrile Citrex Sunfire AC 303630 CHLORFENAPYR 1H-Pyrrole-3-carbonitrile, 4-bromo-2-(4-chlorophenyl)-1-(ethoxymethyl)-5-(trifluoromethyl)- chlorfenapyr (bsi, pa iso) chlorfenapyr 4-bromo-2-(4-chlorophenyl)-1-ethoxymethyl-5-trifluoromethylpyrrole-3-carbonitrile CL 303630 Kotersu Kotetsu Pylon Ccris 9252 Chlorfenapyr [iso] Hsdb 7464 Chlorfenapyr 100mg [122453-73-0] -1-(ethoxymethyl) 4-Bromo-2-(4-chlorophenyl) Chlorfenapyr 0 Chlorfenapyr 4-Bromo-2-(4-chlorophenyl)-1-(ethoxymethyl)-5-(trifluoromethyl)-1H-pyrrol-3-carbonitrile 4-BroMo-2-(p-chlorophenyl)-1-(ethoxyMethyl)-5-(trifluoroMethyl)pyrrole-3-carbonitrile Citrex (acaricide) Mystox MP Pirate 3F Secure 360SC Insecticide-Miticide Stealth Chlorfenapyr Solution, 1000ppm Chlorfenapyr 98% Clorfenapir 98% Good insecticide Chlorfenapyr@1000 μg/mL in Acetone Chlorfenapyr Reference Material ChlorfenapyrSolution,10mg/L,1ml ChlorfenapyrSolution,1,000mg/L,1ml ChlorfenapyrSolution,100mg/L,1ml Chlorfenapyr 24%SC insects acaricide products CAS 122453-73-0 orfenapyr PIRATE STALKER Intrepid Chlorfenapyr 10 μg/mL in Cyclohexane L11247500CY Chlorfenapyr 10μg/mLin Cyclohexan Chlorfenapyr 100 μg/ml Acetonitrile Chlorfenapyr 100 μg/ml Ethyl acetate C11247500 Chlorfenapyr Chlorfenapyr in Methanol Chlorfenapyr-d7 (1-ethoxymethyl-d7) Hexazinone Impurity 19 4-bromo-2-(4-chlorophenyl)-1-ethoxymethyl-5-trifluoromethylpyrrole-3-carbonitrile (Chlorfenapyr) Chlorfenapyr, 10 mM in DMSO Chlorfepyr 50%Chlorfenapyr WDG 36%Chlorfenapyr EV 10%Chlorfenapyr EV Chlorfenapyr (Standard) 4-BROMO-2-(4-CHLOROPHENYL)-1-(ETHOXYMETHYL)-5-(TRIFLUOROMETHYL)-1H-PYRROL-3-CARBONITRILE Alert