ChemicalBook >> CAS DataBase List >>Nimustine
Nimustine
- CAS No.
- 42471-28-3
- Chemical Name:
- Nimustine
- Synonyms
- ACNU;ACNU 50;Nimustin;NIMUSTINE;NITROSOUREA;NIFUMICACID;NIMUSTINE HCL;Nimustine USP/EP/BP;pimustine hydrochloride;1,2-DibroMo-3-chloropropane Standard
- CBNumber:
- CB4231103
- Molecular Formula:
- C9H13ClN6O2
- Molecular Weight:
- 272.69
- MDL Number:
- MFCD00866532
- MOL File:
- 42471-28-3.mol
- MSDS File:
- SDS
Last updated:2023-04-23 13:52:06
| Melting point | 125°C (rough estimate) |
|---|---|
| Boiling point | 98°C (rough estimate) |
| Density | 1.9048 (rough estimate) |
| refractive index | 1.5790 (estimate) |
| pka | 9.58±0.46(Predicted) |
| form | solid |
| CAS DataBase Reference | 42471-28-3(CAS DataBase Reference) |
| FDA UNII | 0S726V972K |
| NCI Dictionary of Cancer Terms | nimustine; nitrosourea |
| NCI Drug Dictionary | nimustine |
| ATC code | L01AD06 |
SAFETY
Risk and Safety Statements
| Hazard Codes | T |
|---|---|
| Risk Statements | 25 |
| Safety Statements | 36/37/39-45 |
| RIDADR | UN 2811 6.1/PG 3 |
| WGK Germany | 3 |
| RTECS | YR8450000 |
Nimustine price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| American Custom Chemicals Corporation | API0003580 | NIMUSTINE 95.00% | 42471-28-3 | 100MG | $402.7 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | API0003580 | NIMUSTINE 95.00% | 42471-28-3 | 1G | $427.5 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | API0003580 | NIMUSTINE 95.00% | 42471-28-3 | 5G | $537.5 | 2021-12-16 | Buy |
| AHH | API-1243 | Nimustine 98% | 42471-28-3 | 10g | $320 | 2021-12-16 | Buy |
Nimustine Chemical Properties,Uses,Production
Originator
Nidran,Sankyo,Japan,1979
Definition
ChEBI: An organochlorine compound that is urea in which the two hydrogens on one of the amino groups are replaced by nitroso and 2-chloroethyl groups and one hydrogen from the other amino group is replaced by a 4-amino-2-methylpyrimidin-5-ylmethyl] group. An anti eoplastic agent especially effective against malignant brain tumors.
Manufacturing Process
0.4 g of sodium nitrite was added with stirring, at 0°C to 5°C, to a solution of
450 mg of 1-(2-chloroethyl)-3-[(2-methyl-4-aminopyridin-5-yl)methyl]urea in
8 ml of 5% hydrochloric acid, and the reaction mixture was then stirred at
0°C to 10°C for an additional 1.5 hours.
After completion of the reaction, the reaction mixture was made alkaline by
the addition of sodium carbonate, whereupon crystals separated out in situ.
The crystals were recovered by filtration, washed with water and then
recrystallized from 6 ml of ethanol, to give 0.1 g of the pale yellow pure
desired product having a decomposition point of 125°C.
Therapeutic Function
Antitumor, Antileukemic
Nimustine Preparation Products And Raw materials
Nimustine Suppliers
Global( 85)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Hubei xin bonus chemical co. LTD | 86-13657291602 | linda@hubeijusheng.com | CHINA | 22968 | 58 |
| Chongqing Chemdad Co., Ltd | +86-023-61398051 +8613650506873 | sales@chemdad.com | China | 39916 | 58 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 47465 | 58 |
| career henan chemical co | +86-0371-86658258 15093356674; | factory@coreychem.com | China | 29826 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 19892 | 58 |
| Hefei TNJ Chemical Industry Co.,Ltd. | 0551-65418671 | sales@tnjchem.com | China | 34572 | 58 |
| Dideu Industries Group Limited | +86-29-89586680 +86-15129568250 | 1026@dideu.com | China | 29322 | 58 |
| Finetech Industry Limited | +86-27-87465837 +8618971612321 | info@finetechnology-ind.com | China | 9702 | 58 |
| ZHEJIANG JIUZHOU CHEM CO., LTD | +86-0576225566889 +86-13454675544 | admin@jiuzhou-chem.com；jamie@jiuzhou-chem.com；alice@jiuzhou-chem.com | China | 20000 | 58 |
| GIHI CHEMICALS CO.,LIMITED | +8618058761490 | info@gihichemicals.com | China | 49999 | 58 |
View Lastest Price from Nimustine manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2021-07-06 | Nimustine USP/EP/BP
42471-28-3
|
US $1.10 / g | 1g | 99.9% | 100 Tons Min | Dideu Industries Group Limited | |
 |
2020-01-09 | Nimustine
42471-28-3
|
US $1.00 / ASSAYS | 1ASSAYS | 85.0-99.8% | 20tons | Career Henan Chemical Co |
-
- Nimustine USP/EP/BP
42471-28-3
- US $1.10 / g
- 99.9%
- Dideu Industries Group Limited
-
- Nimustine
42471-28-3
- US $1.00 / ASSAYS
- 85.0-99.8%
- Career Henan Chemical Co
42471-28-3(Nimustine)Related Search:
1of4
1-(4-AMINO-2-METHYL-5-PYRIMIDINYL)-METHYL-3-(2-CHLOROETHYL)-3-NITROSOUREA HYDROCHLORIDE
1-((4-amino-2-methylpyrimidin-5-yl)methyl)-3-(2-chloroethyl)-3-nitrosourea
NIMUSTINE
NIMUSTINE HCL
N'-[(4-AMINO-2-METHYL-5-PYRIMIDINYL)METHYL]-N-(2-CHLORETHYL)-N-NITROSOUREA
ACNU
3-(4-amino-2-methyl-5-pyrimidinyl)methyl-1-(2-chloroethyl)-1-nitrosourea
n’-((4-amino-2-methyl-5-pyrimidinyl)methyl)-n-(2-chloroethyl)-n-nitroso-ure
Nimustin
1-[(4-Amino-2-methyl-5-pyrimidinyl)methyl]-3-(2-chloroethyl)-3-nitrosourea
3-[(4-Amino-2-methylpyrimidin-5-yl)methyl]-1-(2-chloroethyl)-1-nitrosourea
1,2-DibroMo-3-chloropropane Standard
NITROSOUREA
NIFUMICACID
3-[(4-amino-2-methyl-5-pyrimidinyl)methyl]-1-(2-chloroethyl)-1-nitrosourea hydrochloride
Urea, N'-[(4-amino-2-methyl-5-pyrimidinyl)methyl]-N-(2-chloroethyl)-N-nitroso-
Nimustine USP/EP/BP
ACNU 50
pimustine hydrochloride
NimustineNIMUSTIN
CAS:42471-28-3
CAND-1042 42471-28-3 1996-12-8 42471-28-6 C9H13ClN6O2 DNA Intercalators and Crosslinkers DNA metabolism Apoptosis and Cell Cycle BioChemical Cell Biology Cell Signaling and Neuroscience
CAS:42471-28-3
CAND-1042 42471-28-3 1996-12-8 42471-28-6 C9H13ClN6O2 DNA Intercalators and Crosslinkers DNA metabolism Apoptosis and Cell Cycle BioChemical Cell Biology Cell Signaling and Neuroscience