ChemicalBook >> CAS DataBase List >>(Z)-7-[(1R)-3α,5α-Dihydroxy-2β-[(E,R)-3-hydroxy-4-[3-(trifluoromethyl)phenoxy]-1-butenyl]cyclopentan-1α-yl]-5-heptenoic acid methyl ester

(Z)-7-[(1R)-3α,5α-Dihydroxy-2β-[(E,R)-3-hydroxy-4-[3-(trifluoromethyl)phenoxy]-1-butenyl]cyclopentan-1α-yl]-5-heptenoic acid methyl ester

CAS No.
73275-76-0
Chemical Name:
(Z)-7-[(1R)-3α,5α-Dihydroxy-2β-[(E,R)-3-hydroxy-4-[3-(trifluoromethyl)phenoxy]-1-butenyl]cyclopentan-1α-yl]-5-heptenoic acid methyl ester
Synonyms
Fluprostenol methyl ester;Travoprost Impurity 24(Fluprostenol Methyl Ester);methyl (Z)-7-[(2S)-3,5-dihydroxy-2-[(E)-3-hydroxy-4-[3-(trifluoromethyl)phenoxy]but-1-enyl]cyclopentyl]hept-5-enoate;(Z)-methyl 7-((1R,2R,3R,5S)-3,5-dihydroxy-2-((R,E)-3-hydroxy-4-(3-(trifluoromethyl)phenoxy)but-1-enyl)cyclopentyl)hept-5-enoate;(Z)-7-[(1R)-3α,5α-Dihydroxy-2β-[(E,R)-3-hydroxy-4-[3-(trifluoromethyl)phenoxy]-1-butenyl]cyclopentan-1α-yl]-5-heptenoic acid methyl ester;5-Heptenoic acid, 7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(1E,3R)-3-hydroxy-4-[3-(trifluoromethyl)phenoxy]-1-buten-1-yl]cyclopentyl]-, methyl ester, (5Z)-
CBNumber:
CB42397809
Molecular Formula:
C24H31F3O6
Molecular Weight:
472.49
MDL Number:
MOL File:
73275-76-0.mol
Last updated:2023-06-08 09:03:08

(Z)-7-[(1R)-3α,5α-Dihydroxy-2β-[(E,R)-3-hydroxy-4-[3-(trifluoromethyl)phenoxy]-1-butenyl]cyclopentan-1α-yl]-5-heptenoic acid methyl ester Properties

Boiling point 568.8±50.0 °C(Predicted)
Density 1.281±0.06 g/cm3(Predicted)
storage temp. Store at -20°C
solubility DMF: 50 mg/ml; DMSO: 50 mg/ml; Ethanol: 50 mg/ml; PBS (pH 7.2): 10 mg/ml
pka 13.43±0.20(Predicted)

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictogramsGHS hazard pictograms
GHS02,GHS07
Signal word  Danger
Hazard statements  H225-H319
Precautionary statements  P210-P233-P240-P241-P242-P243-P264-P280-P303+P361+P353-P305+P351+P338-P337+P313-P370+P378-P403+P235-P501
NFPA 704
3
2 0

(Z)-7-[(1R)-3α,5α-Dihydroxy-2β-[(E,R)-3-hydroxy-4-[3-(trifluoromethyl)phenoxy]-1-butenyl]cyclopentan-1α-yl]-5-heptenoic acid methyl ester price More Price(6)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Cayman Chemical 10010151 Fluprostenol methyl ester ≥98% 73275-76-0 1mg $70 2024-03-01 Buy
Cayman Chemical 10010151 Fluprostenol methyl ester ≥98% 73275-76-0 5mg $308 2024-03-01 Buy
Cayman Chemical 10010151 Fluprostenol methyl ester ≥98% 73275-76-0 10mg $545 2024-03-01 Buy
AK Scientific 1008AH (+)-Fluprostenolmethylester 73275-76-0 10mg $704 2021-12-16 Buy
AK Scientific 1008AH (+)-Fluprostenolmethylester 73275-76-0 5mg $440 2021-12-16 Buy
Product number Packaging Price Buy
10010151 1mg $70 Buy
10010151 5mg $308 Buy
10010151 10mg $545 Buy
1008AH 10mg $704 Buy
1008AH 5mg $440 Buy

(Z)-7-[(1R)-3α,5α-Dihydroxy-2β-[(E,R)-3-hydroxy-4-[3-(trifluoromethyl)phenoxy]-1-butenyl]cyclopentan-1α-yl]-5-heptenoic acid methyl ester Chemical Properties,Uses,Production

Description

Fluprostenol is an F-series prostaglandin analog which has been approved for many years as a luteolytic in veterinary animals.1 The isopropyl ester of fluprostenol (travoprost) is an effective ocular hypotensive drug.2

References

1. Dukes, M., Russell, W., and Walpole, A.L. Potent luteolytic agents related to prostaglandin F Nature 250(464),330-331(1974).
2. Sorbera, L.A., and Casta?er, J. Travoprost Drugs Future 25(1),41-45(2000).

(Z)-7-[(1R)-3α,5α-Dihydroxy-2β-[(E,R)-3-hydroxy-4-[3-(trifluoromethyl)phenoxy]-1-butenyl]cyclopentan-1α-yl]-5-heptenoic acid methyl ester Preparation Products And Raw materials

Raw materials

Preparation Products

(Z)-7-[(1R)-3α,5α-Dihydroxy-2β-[(E,R)-3-hydroxy-4-[3-(trifluoromethyl)phenoxy]-1-butenyl]cyclopentan-1α-yl]-5-heptenoic acid methyl ester Suppliers

Global( 16)Suppliers
Supplier Tel Email Country ProdList Advantage
Standardpharm Co. Ltd.
86-714-3992388 overseasales1@yongstandards.com United States 14336 58
China National Standard Pharmaceutical Corporation Limited
+8615391658522 overseasales@yongstandards.com China 11927 58
BOC Sciences 16314854226 info@bocsci.com United States 9926 65
Shanghai Hongye Biotechnology Co. Ltd 400-9205774 sales@glpbio.cn China 6870 58
Hangzhou Synstar pharmaceutical Technology CO.,Ltd 0571-85361029 synstar518@163.com China 1991 58
Guangzhou Dreampharm Biotechnology Co., Ltd. 17825480238 3008233717@qq.com China 9844 12
Jinan blalong chemical co. LTD 2710913286@.com 1513643261@qq.com China 14253 58
ChemeGen(Shanghai) Biotechnology Co.,Ltd. 18818260767 sales@chemegen.com China 11289 58
Guangzhou Juntang Technology Co., Ltd 020-36607679 13502246435 sales@dmstandards.com China 10951 58
TargetMol Chemicals Inc. 4008200310 marketing@tsbiochem.com China 24131 58
Fluprostenol methyl ester (Z)-methyl 7-((1R,2R,3R,5S)-3,5-dihydroxy-2-((R,E)-3-hydroxy-4-(3-(trifluoromethyl)phenoxy)but-1-enyl)cyclopentyl)hept-5-enoate Travoprost Impurity 24(Fluprostenol Methyl Ester) 5-Heptenoic acid, 7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(1E,3R)-3-hydroxy-4-[3-(trifluoromethyl)phenoxy]-1-buten-1-yl]cyclopentyl]-, methyl ester, (5Z)- methyl (Z)-7-[(2S)-3,5-dihydroxy-2-[(E)-3-hydroxy-4-[3-(trifluoromethyl)phenoxy]but-1-enyl]cyclopentyl]hept-5-enoate (Z)-7-[(1R)-3α,5α-Dihydroxy-2β-[(E,R)-3-hydroxy-4-[3-(trifluoromethyl)phenoxy]-1-butenyl]cyclopentan-1α-yl]-5-heptenoic acid methyl ester 73275-76-0 C24H31F3O6