ChemicalBook >> CAS DataBase List >>Z-Vad-fmk, non-methylated

Z-Vad-fmk, non-methylated

CAS No.
161401-82-7
Chemical Name:
Z-Vad-fmk, non-methylated
Synonyms
Z-VAD;abs817872;Z-VAD-FMK, Free Acid;Z-VAD-FMK (Caspase Inhibitor VI);Z-VAD(OH)-FMK (Caspase Inhibitor VI);Z-VAL-ALA-ASP-(OH)-FLUOROMETHYL KETONE;Caspase Inhibitor VI - CAS 161401-82-7 - Calbiochem;Carbobenzyloxy-Val-Ala-Asp-alpha-fluoromethylketone;inhibit,Inhibitor,ZVADFMK,Hela,Z VAD FMK,Caspase,Antiapoptosis,cells,pan-caspase;L-Alaninamide, N-[(phenylmethoxy)carbonyl]-L-valyl-N-[(1S)-1-(carboxymethyl)-3-fluoro-2-oxopropyl]-
CBNumber:
CB42497499
Molecular Formula:
C21H28FN3O7
Molecular Weight:
453.46
MDL Number:
MOL File:
161401-82-7.mol
MSDS File:
SDS
Last updated:2023-09-04 16:42:00

Z-Vad-fmk, non-methylated Properties

Boiling point 758.0±60.0 °C(Predicted)
Density 1.260±0.06 g/cm3(Predicted)
storage temp. -20°C
solubility DMSO:5.0(Max Conc. mg/mL);11.0(Max Conc. mM)
pka 3.91±0.19(Predicted)
form Off-white solid

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P261-P305+P351+P338

Z-Vad-fmk, non-methylated price More Price(12)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 219007 Caspase Inhibitor VI - CAS 161401-82-7 - Calbiochem Z-VAD-FMK, CAS 161401-82-7, is an irreversible pan caspase inhibitor. Does not require pretreatment with esterase for in vitro studies. 161401-82-7 250μg $113 2024-03-01 Buy
Sigma-Aldrich 219007 Caspase Inhibitor VI - CAS 161401-82-7 - Calbiochem
Z-VAD-FMK, CAS 161401-82-7, is an irreversible pan caspase inhibitor. Does not require pretreatment with esterase for in vitro studies.
161401-82-7 1mg $303 2024-03-01 Buy
Cayman Chemical 14467 Z-VAD(OH)-FMK ≥95% 161401-82-7 500μg $73 2024-03-01 Buy
Cayman Chemical 14467 Z-VAD(OH)-FMK ≥95% 161401-82-7 1mg $131 2024-03-01 Buy
Cayman Chemical 14467 Z-VAD(OH)-FMK ≥95% 161401-82-7 5mg $380 2024-03-01 Buy
Product number Packaging Price Buy
219007 250μg $113 Buy
219007 1mg $303 Buy
14467 500μg $73 Buy
14467 1mg $131 Buy
14467 5mg $380 Buy

Z-Vad-fmk, non-methylated Chemical Properties,Uses,Production

Description

Z-VAD(OH)-FMK is an irreversible tripeptide inhibitor of all caspases. This non-methylated form is useful in studies involving recombinant, isolated, or purified enzymes. Unlike the methylated form, Z-VAD(OMe)-FMK , this compound does not require pretreatment with esterases prior to in vitro use.

General Description

An irreversible general caspase inhibitor. Useful for studies involving recombinant, isolated, and purified caspase enzymes. Unlike Caspase Inhibitor I (Cat. No. 627610), this inhibitor does not require pretreatment with esterase for in vitro studies. A 10 mM (1 mg/221 μl) solution of Caspase Inhibitor VI (Cat. No. 219011) in DMSO is also available.

Biochem/physiol Actions

Product does not compete with ATP.

Z-Vad-fmk, non-methylated Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 56)Suppliers
Supplier Tel Email Country ProdList Advantage
ATK CHEMICAL COMPANY LIMITED
+undefined-21-51877795 ivan@atkchemical.com China 32480 60
InvivoChem
+1-708-310-1919 +1-13798911105 sales@invivochem.cn United States 6393 58
Nantong HI-FUTURE Biology Co., Ltd.
+undefined18051384581 sales@chemhifuture.com China 3136 58
TargetMol Chemicals Inc.
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LEAPCHEM CO., LTD.
+86-852-30606658 market18@leapchem.com China 43348 58
Shanghai Acmec Biochemical Technology Co., Ltd.
+undefined18621343501 product@acmec-e.com China 33349 58
Aladdin Scientific
+1-833-552-7181 sales@aladdinsci.com United States 57511 58
Shanghai Zhengyi Pharmaceutical Co., Ltd 17740884366 derek1229@163.com China 61 58
Nantong Hi-Future Biotechnology Co., Ltd 18051384581 sales@chemhifuture.com China 2996 58
Chembest Research Laboratories Limited 021-20908456 sales@BioChemBest.com China 6011 61

Z-Vad-fmk, non-methylated Spectrum

Z-VAL-ALA-ASP-(OH)-FLUOROMETHYL KETONE Z-VAD-FMK (Caspase Inhibitor VI) Carbobenzyloxy-Val-Ala-Asp-alpha-fluoromethylketone L-Alaninamide, N-[(phenylmethoxy)carbonyl]-L-valyl-N-[(1S)-1-(carboxymethyl)-3-fluoro-2-oxopropyl]- L-Alaninamide, N-[(phenylmethoxy)carbonyl]-L-valyl-N-[(1S)-1-(carboxymethyl)-3-fluoro-2-oxopropyl]- (9ci) L-Alaninamide, N-[(phenylmethoxy)carbonyl]-L-valyl-N-[1-(carboxymethyl)-3-fluoro-2-oxopropyl]-, (S)- Z-VAD-FMK, Free Acid Z-VAD(OH)-FMK (Caspase Inhibitor VI) Caspase Inhibitor VI - CAS 161401-82-7 - Calbiochem abs817872 (5S,8S,11S)-11-(2-Fluoroacetyl)-5-isopropyl-8-methyl-3,6,9-trioxo-1-phenyl-2-oxa-4,7,10-triazatridecan-13-oic acid Z-VAD inhibit,Inhibitor,ZVADFMK,Hela,Z VAD FMK,Caspase,Antiapoptosis,cells,pan-caspase 161401-82-7 C21H28FN3O7