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Ru 24969

Ru 24969 Structure
Ru 24969 structure
CAS No.
66611-27-6
Chemical Name:
Ru 24969
Synonyms
RU 24969 hemisuccinate >=98% (HPLC);RU 24969 hemisuccinate, 5-HT1A/1B agonist;5-Methoxy-3-(1,2,3,6-tetrahydro-4-pyridinyl)-1H-indole succinate (2:1);1H-Indole, 5-methoxy-3-(1,2,3,6-tetrahydro-4-pyridinyl)-, succinate (2:1);1H-Indole, 5-methoxy-3-(1,2,3,6-tetrahydro-4-pyridinyl)-, butanedioate (2:1);Butanedioic acid, compd. with 5-methoxy-3-(1,2,3,6-tetrahydro-4-pyridinyl)-1H-indole (1:2);5-hydroxytryptamine Receptor,fluid,locomotion,5-HT1B,RU 24969 hemisuccinate,inhibit,5-HT Receptor,Inhibitor,Serotonin Receptor,5-HT1A;Butanedioic acid, compd. with5-methoxy-3-(1,2,3,6-tetrahydro-4-pyridinyl)-1H-indole (1:2)OTHER CA INDEX NAMES:1H-Indole, 5-methoxy-3-(1,2,3,6-tetrahydro-4-pyridinyl)-, butanedioate(2:1)
CBNumber:
CB42498007
Molecular Formula:
C32H38N4O6
Molecular Weight:
574.66732
MDL Number:
MFCD09878262
MOL File:
66611-27-6.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-04-24 14:58:19
Product description Number Pack Size Price
RU 24969 hemisuccinate ≥98% (HPLC) SML2013 5MG $85.8
RU 24969 hemisuccinate ≥98% (HPLC) SML2013 25MG $347
RU24969Succinate(2:1) R701779 10mg $105
RU24969Hemisuccinate CSN23080 10mg $119
RU24969Hemisuccinate CSN23080 25mg $260
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Ru 24969 Properties

storage temp. Store at -20°C
solubility DMF: slightly soluble,DMSO: slightly soluble,Ethanol: slightly soluble,PBS (pH 7.2): 1 mg/ml
form A crystalline solid
color yellow to yellow-orange
Water Solubility H2O: 2mg/mL, clear (warmed)
InChI 1S/2C14H16N2O.C4H6O4/c2*1-17-11-2-3-14-12(8-11)13(9-16-14)10-4-6-15-7-5-10;5-3(6)1-2-4(7)8/h2*2-4,8-9,15-16H,5-7H2,1H3;1-2H2,(H,5,6)(H,7,8)
InChIKey BNYJLRQAWCQJOM-UHFFFAOYSA-N
SMILES COC1=CC2=C(NC=C2C3=CCNCC3)C=C1.OC(CCC(O)=O)=O.COC4=CC5=C(NC=C5C6=CCNCC6)C=C4
EWG's Food Scores 1
UNSPSC Code 12352200
NACRES NA.77

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P261-P280-P301+P312-P302+P352-P305+P351+P338
WGK Germany  WGK 3
Storage Class 11 - Combustible Solids

Ru 24969 price More Price(6)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich SML2013 RU 24969 hemisuccinate ≥98% (HPLC) 66611-27-6 5MG $85.8 2026-03-19 Buy
Sigma-Aldrich SML2013 RU 24969 hemisuccinate ≥98% (HPLC) 66611-27-6 25MG $347 2026-03-19 Buy
TRC R701779 RU24969Succinate(2:1) 66611-27-6 10mg $105 2021-12-16 Buy
CSNpharm CSN23080 RU24969Hemisuccinate 66611-27-6 10mg $119 2021-12-16 Buy
CSNpharm CSN23080 RU24969Hemisuccinate 66611-27-6 25mg $260 2021-12-16 Buy
Product number Packaging Price Buy
SML2013 5MG $85.8 Buy
SML2013 25MG $347 Buy
R701779 10mg $105 Buy
CSN23080 10mg $119 Buy
CSN23080 25mg $260 Buy

Ru 24969 Chemical Properties,Uses,Production

Uses

RU 24969 Succinate (2:1), is a SR-1A and SR-1B, and moderate SR-2C agonist. 5-HT1B/1A agonist. Also, it is a well-established substrate for human serotonin transporter (SERT).

Biological Activity

RU-24969 is a potent and selective agonist at the 5-HT1A and 5-HT1B receptors.

in vivo

RU 24969 (0.03-3.0 mg/kg; s.c.) dose-dependently decreases water consumption in water deprived rats[1].
RU 24969 (0.3-3.0 mg/kg; s.c.) dose-dependently increases forward locomotion[1].

Animal Model:Male Sprague-Dawley rats[1]
Dosage:0.03, 0.3, 1.0, 3.0 mg/kg
Administration:A single s.c.
Result:Decreased water consumption significantly at dose of 0.3, 1.0, and 3.0 mg/kg.

IC 50

5-HT1B Receptor: 0.38 nM (Ki); 5-HT1A Receptor: 2.5 nM (Ki)

storage

Store at RT

Ru 24969 Preparation Products And Raw materials

Raw materials

Preparation Products

Ru 24969 Suppliers

Global( 24)Suppliers
Supplier Tel Email Country ProdList Advantage
TargetMol Chemicals Inc. 		+1-781-999-5354; +17819995354 marketing@targetmol.com United States 32467 58
Aladdin Scientific 		tp@aladdinsci.com United States 57505 58
Chembest Research Laboratories Limited 021-20908456 sales@BioChemBest.com China 6003 61
Shanghai YuanYe Biotechnology Co., Ltd. 021-61312847; 18021002903 3008007409@qq.com China 86249 60
Shanghai Hongye Biotechnology Co. Ltd 400-9205774 sales@glpbio.cn China 6777 58
BOC Sciences -- info@bocsci.com USA 0 65
ChemeGen(Shanghai) Biotechnology Co.,Ltd. 18818260767 sales@chemegen.com China 11218 58
Energy Chemical 021-58432009 400-005-6266 marketing@energy-chemical.com China 44918 58
Shanghai Maclean Biochemical Technology Co., LTD 021-50706066 15221275939 shenlinxing@macklin.cn China 29680 58
Shanghai Yifei Biotechnology Co. , Ltd. 021-65675885 18964387627 customer_service@efebio.com China 11972 58
Supplier Advantage
TargetMol Chemicals Inc. 		58
Aladdin Scientific 		58
Chembest Research Laboratories Limited 61
Shanghai YuanYe Biotechnology Co., Ltd. 60
Shanghai Hongye Biotechnology Co. Ltd 58
BOC Sciences 65
ChemeGen(Shanghai) Biotechnology Co.,Ltd. 58
Energy Chemical 58
Shanghai Maclean Biochemical Technology Co., LTD 58
Shanghai Yifei Biotechnology Co. , Ltd. 58
1H-Indole, 5-methoxy-3-(1,2,3,6-tetrahydro-4-pyridinyl)-, butanedioate (2:1) 1H-Indole, 5-methoxy-3-(1,2,3,6-tetrahydro-4-pyridinyl)-, succinate (2:1) 5-Methoxy-3-(1,2,3,6-tetrahydro-4-pyridinyl)-1H-indole succinate (2:1) Butanedioic acid, compd. with 5-methoxy-3-(1,2,3,6-tetrahydro-4-pyridinyl)-1H-indole (1:2) Butanedioic acid, compd. with5-methoxy-3-(1,2,3,6-tetrahydro-4-pyridinyl)-1H-indole (1:2)OTHER CA INDEX NAMES:1H-Indole, 5-methoxy-3-(1,2,3,6-tetrahydro-4-pyridinyl)-, butanedioate(2:1) RU 24969 hemisuccinate >=98% (HPLC) 5-hydroxytryptamine Receptor,fluid,locomotion,5-HT1B,RU 24969 hemisuccinate,inhibit,5-HT Receptor,Inhibitor,Serotonin Receptor,5-HT1A RU 24969 hemisuccinate, 5-HT1A/1B agonist 66611-27-6 2C14H16N2OC4H6O4 C4H6O42C14H16N2O