ChemicalBook >> CAS DataBase List >>Trandolapril Related Compound D (25 mg) ((S)-ethyl 2-[(3S, 5aS, 9aR, 10aS)-3-methyl-1,4-dioxodecahydropyrazino[1,2-a]indol-2(1H)-yl]-4-phenylbutanoate)

Trandolapril Related Compound D (25 mg) ((S)-ethyl 2-[(3S, 5aS, 9aR, 10aS)-3-methyl-1,4-dioxodecahydropyrazino[1,2-a]indol-2(1H)-yl]-4-phenylbutanoate)

CAS No.
149881-40-3
Chemical Name:
Trandolapril Related Compound D (25 mg) ((S)-ethyl 2-[(3S, 5aS, 9aR, 10aS)-3-methyl-1,4-dioxodecahydropyrazino[1,2-a]indol-2(1H)-yl]-4-phenylbutanoate)
Synonyms
RU 46178;TRANDOLAPRIL SRS LACTAM;Trandolapril EP IMpurity D;Trandolapril Diketopiperazine;Trandolapril Related CoMpound D;Trandolapril EP Impurity D (USP RC D);Trandolapril Impurity 4(Trandolapril EP Impurity D);Trandolapril EP Impurity D/ Trandolapril Related Compound D (Trandolapril Diketopiperazine);(S)-ethyl 2-[(3S,5aS,9aR,10aS)-3-Methyl-1,4-dioxodecahydropyrazino[1,2-a]indol-2(1H)-yl]-4-phenylbutanoate;Ethyl (2S)-2-[(3S,5aS,9aR,10aS)-3-methyl-1,4-dioxodecahydropyrazino[1,2-a]indol-2(1H)-yl]-4-phenylbutanoate
CBNumber:
CB42567651
Molecular Formula:
C24H32N2O4
Molecular Weight:
412.52
MDL Number:
MOL File:
149881-40-3.mol
Last updated:2023-04-23 13:52:06

Trandolapril Related Compound D (25 mg) ((S)-ethyl 2-[(3S, 5aS, 9aR, 10aS)-3-methyl-1,4-dioxodecahydropyrazino[1,2-a]indol-2(1H)-yl]-4-phenylbutanoate) Properties

Melting point 153-155°C
Boiling point 607.5±55.0 °C(Predicted)
Density 1.21±0.1 g/cm3(Predicted)
storage temp. 2-8°C
solubility Chloroform (Slightly), Methanol (Slightly)
pka -1.16±0.40(Predicted)
color White to Off-White
FDA UNII 4768A319U6

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS08
Signal word  Warning
Hazard statements  H361d-H373
Precautionary statements  P202-P260-P280-P308+P313-P405-P501
HS Code  2933997500

Trandolapril Related Compound D (25 mg) ((S)-ethyl 2-[(3S, 5aS, 9aR, 10aS)-3-methyl-1,4-dioxodecahydropyrazino[1,2-a]indol-2(1H)-yl]-4-phenylbutanoate) price More Price(5)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich Y0000496 Trandolapril impurity D European Pharmacopoeia (EP) Reference Standard 149881-40-3 y0000496 $150 2024-03-01 Buy
Sigma-Aldrich PHR3601 Trandolapril Related Compound D certified reference material, pharmaceutical secondary standard 149881-40-3 50MG $688 2024-03-01 Buy
Sigma-Aldrich 1672712 Trandolapril impurity D 149881-40-3 25mg $484 2024-03-01 Buy
TRC T713515 TrandolaprilDiketopiperazine 149881-40-3 25mg $180 2021-12-16 Buy
Medical Isotopes, Inc. 53226 TrandolaprilDiketopiperazine 149881-40-3 100mg $2200 2021-12-16 Buy
Product number Packaging Price Buy
Y0000496 y0000496 $150 Buy
PHR3601 50MG $688 Buy
1672712 25mg $484 Buy
T713515 25mg $180 Buy
53226 100mg $2200 Buy

Trandolapril Related Compound D (25 mg) ((S)-ethyl 2-[(3S, 5aS, 9aR, 10aS)-3-methyl-1,4-dioxodecahydropyrazino[1,2-a]indol-2(1H)-yl]-4-phenylbutanoate) Chemical Properties,Uses,Production

Uses

Trandolapril Diketopiperazine (Trandolapril EP Impurity D) is a metabolite of the antihypertensive Trandolapril (Ru44570) (T713500), an angiotensin-converting enzyme inhibitor.

Uses

Trandolapril Diketopiperazine is a metabolite of the antihypertensive Trandolapril (Ru44570) (T713500), an angiotensin-converting enzyme inhibitor.

Trandolapril Related Compound D (25 mg) ((S)-ethyl 2-[(3S, 5aS, 9aR, 10aS)-3-methyl-1,4-dioxodecahydropyrazino[1,2-a]indol-2(1H)-yl]-4-phenylbutanoate) Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 31)Suppliers
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(αS,3S,5aS,9aR,10aS)-Decahydro-3-Methyl-1,4-dioxo-α-(2-phenylethyl)pyrazino[1,2-a]indole-2(1H)-acetic Acid Ethyl Ester RU 46178 Trandolapril Diketopiperazine (alphaS,3S,5aS,9aR,10aS)-Decahydro-3-methyl-1,4-dioxo-alpha-(2-phenylethyl)pyrazino[1,2-a]indole-2(1H)-acetic acid ethyl ester Ethyl (2S)-2-[(3S,5aS,9aR,10aS)-3-methyl-1,4-dioxodecahydropyrazino[1,2-a]indol-2(1H)-yl]-4-phenylbutanoate Trandolapril EP IMpurity D Trandolapril Related CoMpound D Trandolapril EP Impurity D (USP RC D) Trandolapril Impurity 4(Trandolapril EP Impurity D) Pyrazino[1,2-a]indole-2(1H)-acetic acid, decahydro-3-methyl-1,4-dioxo-α-(2-phenylethyl)-, ethyl ester, (αS,3S,5aS,9aR,10aS)- Trandolapril EP Impurity D/ Trandolapril Related Compound D (Trandolapril Diketopiperazine) Trandolapril EP Impurity DQ: What is Trandolapril EP Impurity D Q: What is the CAS Number of Trandolapril EP Impurity D Q: What is the storage condition of Trandolapril EP Impurity D Q: What are the applications of Trandolapril EP Impurity D (S)-ethyl 2-[(3S,5aS,9aR,10aS)-3-Methyl-1,4-dioxodecahydropyrazino[1,2-a]indol-2(1H)-yl]-4-phenylbutanoate Trandolapril Related Compound D ((S)-ethyl 2-[(3S, 5aS, 9aR, 10aS)-3-methyl-1,4-dioxodecahydropyraz (1672712) ethyl (2S)-2-[(3S,5aS,9aR,10aS)-3-methyl-1,4-dioxodecahydropyrazino[1,2-a]indol-2(1H)-yl]-4-phenylbutanoate (trandolapril diketopiperazine) TRANDOLAPRIL SRS LACTAM 149881-40-3 Metabolites & Impurities Pharmaceuticals Aromatics Chiral Reagents Heterocycles Intermediates & Fine Chemicals