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Rimegepant

Rimegepant Structure
Rimegepant structure
CAS No.
1289023-67-1
Chemical Name:
Rimegepant
Synonyms
BMS-927711;BMS 927711;CS-2806;BHV-3000;BMS 92771;Rimegepan;Remazepam;Rimegepant;BMS927711;BMS 927711;Rimegepant (BMS927711)
CBNumber:
CB42645135
Molecular Formula:
C28H28F2N6O3
Molecular Weight:
534.56
MDL Number:
MFCD23098777
MOL File:
1289023-67-1.mol
Last updated:2023-09-05 17:53:06
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Rimegepant Properties

Density 1.45±0.1 g/cm3(Predicted)
storage temp. Store at -20°C
solubility Soluble in DMSO
form A crystalline solid
pka 12.03±0.20(Predicted)
FDA UNII 997WVV895X

Rimegepant price More Price(22)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Cayman Chemical 26338 Rimegepant 1289023-67-1 1mg $43 2023-06-20 Buy
Cayman Chemical 26338 Rimegepant 1289023-67-1 5mg $189 2023-06-20 Buy
Cayman Chemical 26338 Rimegepant 1289023-67-1 10mg $334 2023-06-20 Buy
Cayman Chemical 26338 Rimegepant 1289023-67-1 25mg $678 2023-06-20 Buy
TRC R517100 Rimegepant 1289023-67-1 500mg $15225 2021-12-16 Buy
Product number Packaging Price Buy
26338 1mg $43 Buy
26338 5mg $189 Buy
26338 10mg $334 Buy
26338 25mg $678 Buy
R517100 500mg $15225 Buy

Rimegepant Chemical Properties,Uses,Production

Description

Rimegepant (Nurtec ODT)(FDA approved in February 2020) is an ODT available in a single strength of 75 mg for the acute treatment of migraine with or without aura in adults.No more than 75 mg should be taken in a 24-hour period. while there are no contraindications，concomitant administration with CYP3A4 inhibitors should be avoided.The most common adverse reaction is nausea, occurring in few patients (rimegepant PI, 2020). In clinical trials, a single 75-mg dose of rimegepant demonstrated superiority over placebo with regard to freedom from pain (21% in the rimegepant group vs.11% in the placebo group) and freedom from the most bothersome symptom (35% vs. 27%) at 2 hours post dose (Croop et al., 2019). Rimegepant is not approved for migraine prevention, although it is presently in late-stage clinical trials assessing it for that indication(NCT03732638,2020).

Uses

Rimegepant is an oral calcitonin gene-related peptide (CGRP) receptor antagonist used for the treatment of migraine.

Rimegepant synthesis

1289023-63-7
1289023-67-1
Synthesis of Rimegepant from 1-Piperidinecarboxylic acid, 4-(2,3-dihydro-2-oxo-1H-imidazo[4,5-b]pyridin-1-yl)-, (5S,6S,9R)-5-azido-6-(2,3-difluorophenyl)-6,7,8,9-tetrahydro-5H-cyclohepta[b]pyridin-9-yl ester

Rimegepant Preparation Products And Raw materials

Raw materials

1-Piperidinecarboxylic acid, 4-(2,3-dihydro-2-oxo-1H-imidazo[4,5-b]pyridin-1-yl)-, (5S,6S,9R)-5-azido-6-(2,3-difluorophenyl)-6,7,8,9-tetrahydro-5H-cyclohepta[b]pyridin-9-yl ester

Preparation Products

Rimegepant Suppliers

Global( 178)Suppliers
Supplier Tel Email Country ProdList Advantage
Changsha Junyu Chemexpress.co., Ltd
+86-13723890100 info@csjyyy.cn China 134 58
Senova Technology Co. Ltd.
+86-0755-86703119 +8618503098836 info@senovatech.com China 349 58
Hebei Yanxi Chemical Co., Ltd. 		+8617531190177 peter@yan-xi.com China 5993 58
shandong perfect biotechnology co.ltd 		+86-53169958659; +8618596095638 sales@sdperfect.com China 294 58
Zhengzhou Anbu Chem Co.,Ltd 		+86-0371-88006763; +8615988602810 sales@anbuchem.com China 3000 58
Shanghai Daken Advanced Materials Co.,Ltd 		+86-371-66670886 info@dakenam.com China 15371 58
Jinan Carbotang Biotech Co.,Ltd. 		+8615866703830 figo.gao@foxmail.com China 6992 58
SHANGHAI T&W PHARMACEUTICAL CO., LTD. 		+86-021-61551413 +8618813727289 contact@trustwe.com China 5738 58
HANGZHOU CLAP TECHNOLOGY CO.,LTD 		86-571-88216897,88216896 13588875226 sales@hzclap.com CHINA 6313 58
Shanghai UCHEM Inc. 		+862156762820 +86-13564624040 sales@myuchem.com China 6711 58
Supplier Advantage
Changsha Junyu Chemexpress.co., Ltd
58
Senova Technology Co. Ltd.
58
Hebei Yanxi Chemical Co., Ltd. 		58
shandong perfect biotechnology co.ltd 		58
Zhengzhou Anbu Chem Co.,Ltd 		58
Shanghai Daken Advanced Materials Co.,Ltd 		58
Jinan Carbotang Biotech Co.,Ltd. 		58
SHANGHAI T&W PHARMACEUTICAL CO., LTD. 		58
HANGZHOU CLAP TECHNOLOGY CO.,LTD 		58
Shanghai UCHEM Inc. 		58

View Lastest Price from Rimegepant manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
BMS-927711 pictures 2024-03-12 BMS-927711
1289023-67-1
 US $0.00 / g 1g 98% HPLC 100kg shandong perfect biotechnology co.ltd
Rimegepant pictures 2023-09-05 Rimegepant
1289023-67-1
 US $20.00 / KG 1KG 0.99 20 Hebei Yanxi Chemical Co., Ltd.
Rimegepant pictures 2023-07-15 Rimegepant
1289023-67-1
 US $0.00 / KG 0.1KG 98% 1000KGS Zhengzhou Anbu Chem Co.,Ltd
  • BMS-927711 pictures
  • BMS-927711
    1289023-67-1
  • US $0.00 / g
  • 98% HPLC
  • shandong perfect biotechnology co.ltd
  • Rimegepant pictures
  • Rimegepant
    1289023-67-1
  • US $20.00 / KG
  • 0.99
  • Hebei Yanxi Chemical Co., Ltd.
  • Rimegepant pictures
  • Rimegepant
    1289023-67-1
  • US $0.00 / KG
  • 98%
  • Zhengzhou Anbu Chem Co.,Ltd

Rimegepant Spectrum

Rimegepant(1289023-67-1)1HNMR
4-(2,3-Dihydro-2-oxo-1H-imidazo[4,5-b]pyridin-1-yl)-1-piperidinecarboxylic acid (5S,6S,9R)-5-amino-6-(2,3-difluorophenyl)-6,7,8,9-tetrahydro-5H-cyclohepta[b]pyridin-9-yl ester Rimegepant CS-2806 BMS-927711(Rimegepant) BMS 92771 RIMEGEPANT;BMS-927711;BMS927711;BMS 92771 (5S,6S,9R)-5-amino-6-(2,3-difluorophenyl)-6,7,8,9-tetrahydro-5H-cyclohepta[b]pyridin-9-yl 4-(2-oxo-2,3-dihydro-1H-imidazo[4,5-b]pyridin-1-yl)piperidine-1-carboxylate 1-Piperidinecarboxylic acid, 4-(2,3-dihydro-2-oxo-1H-imidazo[4,5-b]pyridin-1-yl)-, (5S,6S,9R)-5-amino-6-(2,3-difluorophenyl)-6,7,8,9-tetrahydro-5H-cyclohepta[b]pyridin-9-yl ester BMS927711;BMS 927711 BHV-3000 Rimegepant (BMS927711) BMS 927711 BMS-927711 Rimegepan Remazepam 1289023-67-1 C28H28F2N6O3 API 1289023-67-1