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AGI6780

Description In vitro
AGI6780
AGI6780 structure
CAS No.
1432660-47-3
Chemical Name:
AGI6780
Synonyms
CS-1905;CS-1019;AGI6780;AGI-6780, >=98%;AGI6780 USP/EP/BP;AGI-6780, that potently and selectively inhibits the tumor-associated mutant IDH2R140Q;N-cyclopropyl-4-(thiophen-3-yl)-3-(3-(3-(trifluoroMethyl)phenyl)ureido)benzenesulfonaMide;N-Cyclopropyl-4-(3-thienyl)-3-[[[[3-(trifluoromethyl)phenyl]amino]carbonyl]amino]-benzenesulfonamide;Benzenesulfonamide, N-cyclopropyl-4-(3-thienyl)-3-[[[[3-(trifluoromethyl)phenyl]amino]carbonyl]amino]-;N-Cyclopropyl-4-(3-thienyl)-3-[[[[3-(trifluoromethyl)phenyl]amino]carbonyl]amino]-benzenesulfonamide AGI-6780
CBNumber:
CB42652324
Molecular Formula:
C21H18F3N3O3S2
Formula Weight:
481.51
MOL File:
1432660-47-3.mol

AGI6780 Properties

Density 
1.52±0.1 g/cm3(Predicted)
pka
11.78±0.20(Predicted)

AGI6780 price More Price(4)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 5.09880 IDH2 Inhibitor, R140Q Somatic Mutant-Specific, AGI-6780 - CAS 1432660-47-3 - Calbiochem 1432660-47-3 5098800001 $214 2020-08-18 Buy
Cayman Chemical 14639 AGI-6780 ≥98% 1432660-47-3 1mg $35 2021-03-22 Buy
Cayman Chemical 14639 AGI-6780 ≥98% 1432660-47-3 5mg $91 2021-03-22 Buy
Cayman Chemical 14639 AGI-6780 ≥98% 1432660-47-3 10mg $165 2021-03-22 Buy

AGI6780 Chemical Properties,Uses,Production

Description

AGI-6780 is a potent and selective inhibitor of IDH2 R140Q mutant with IC50 of 23 nM.

In vitro

AGI-6780 potently reduce (R)-2-hydroxyglutarate (2HG) levels in cell lines ectopically overexpressing IDH2/R140Q with EC50 of 20 nM, with excellent selectivity against other dehydrogenases. AGI-6780 reverses the IDH2/R140Q-induced differentiation block in TF-1 cells, and induces blast differentiation in primary human IDH2/R140Q AML patient samples.

AGI6780 Preparation Products And Raw materials

Raw materials

Preparation Products


AGI6780 Suppliers

Global( 94)Suppliers
Supplier Tel Fax Email Country ProdList Advantage
ATK CHEMICAL COMPANY LIMITED
+86 21 5161 9050/ 5187 7795
+86 21 5161 9052/ 5187 7796 ivan@atkchemical.com CHINA 26734 60
career henan chemical co
+86-371-86658258
sales@coreychem.com CHINA 29961 58
Hubei Jusheng Technology Co.,Ltd.
86-18871470254
027-59599243 linda@hubeijusheng.com CHINA 28229 58
Chongqing Chemdad Co., Ltd
+86-13650506873
sales@chemdad.com CHINA 37282 58
Shaanxi Dideu Medichem Co. Ltd
13772537765
029-88380327 1010@dideu.com CHINA 3993 58
Target Molecule Corp
18019718960 781-999-5354
marketing@targetmol.com United States 19232 58
HANGZHOU CLAP TECHNOLOGY CO.,LTD
13588875226 86-571-88216897、88216896
86-571-88216895 sales@hzclap.com CHINA 6469 58
Dideu Industries Group Limited
029-88380327
Service@dideu.com CHINA 29991 58
Amadis Chemical Company Limited
0086-571-89925085
0086-571-89925065 sales@amadischem.com China 132148 58
Shanghai Boyle Chemical Co., Ltd.
86-21-57758967 sales@boylechem.com China 2926 55

View Lastest Price from AGI6780 manufacturers

Image Release date Product Price Min. Order Purity Supply Ability Manufacturer
2021-07-20 AGI6780
1432660-47-3
US $0.00-0.00 / KG 5g 99% HPLC 2000tons Shaanxi Dideu Medichem Co. Ltd
2019-07-06 AGI6780
1432660-47-3
US $1.00 / KG 1G 98% 100KG career henan chemical co

1432660-47-3(AGI6780)Related Search:


  • AGI-6780 N-Cyclopropyl-4-(3-thienyl)-3-[[[[3-(trifluoromethyl)phenyl]amino]carbonyl]amino]-benzenesulfonamide
  • N-Cyclopropyl-4-(3-thienyl)-3-[[[[3-(trifluoromethyl)phenyl]amino]carbonyl]amino]-benzenesulfonamide AGI-6780
  • AGI6780
  • AGI-6780, >=98%
  • N-cyclopropyl-4-(thiophen-3-yl)-3-(3-(3-(trifluoroMethyl)phenyl)ureido)benzenesulfonaMide
  • N-Cyclopropyl-4-(3-thienyl)-3-[[[[3-(trifluoromethyl)phenyl]amino]carbonyl]amino]-benzenesulfonamide
  • Benzenesulfonamide, N-cyclopropyl-4-(3-thienyl)-3-[[[[3-(trifluoromethyl)phenyl]amino]carbonyl]amino]-
  • CS-1019
  • CS-1905
  • AGI6780 USP/EP/BP
  • AGI-6780, that potently and selectively inhibits the tumor-associated mutant IDH2R140Q
  • 1432660-47-3
  • C21H18F3N3O3S2
  • Inhibitors
  • API
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