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PSI-7976

PSI-7976 structure

CAS No.: 1190308-01-0

Chemical Name:: PSI-7976

Synonyms: PSI-7976;SFB-L-ALANITE-MODEL;SFB-L-Alaninate-Model;Sofosbuvir (R)-Phosphate;Sofosbuvir phosphate salt;N-[[P(R),2'R]-2'-Deoxy-2'-fluoro-2'-methyl-P-phenyl-5'-uridylyl]-L-alanine 1-methylethyl ester;L-Alanine, N-[[P(R),2'R]-2'-deoxy-2'-fluoro-2'-methyl-P-phenyl-5'-uridylyl]-, 1-methylethyl ester;isopropyl ((R)-(((2R,3R,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-4-fluoro-3-hydroxy-4-methyltetrahydrofuran-2-yl)methoxy)(phenoxy)phosphoryl)-L-alanite;isopropyl ((R)-(((2R,3R,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-4-fluoro-3-hydroxy-4-methyltetrahydrofuran-2-yl)methoxy)(phenoxy)phosphoryl)-Lalaninate;(S)-isopropyl 2-((R)-(((2R,3R,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-4-fluoro-3-hydroxy-4-methyltetrahydrofuran-2-yl)methoxy)(phenoxy)phosphorylamino)propanoate

CBNumber:: CB42685935

Molecular Formula:: C22H29FN3O9P

Molecular Weight:: 529.45

MDL Number:

MOL File:: 1190308-01-0.mol

Last updated:2023-05-18 11:31:12

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PSI-7976 Properties

Melting point	76-82°C
Density	1.41±0.1 g/cm3(Predicted)
storage temp.	-20°C Freezer
solubility	Chloroform (Slightly), DMSO (Slightly), Ethyl Aceatae (Slightly)
pka	9.39±0.10(Predicted)
form	Solid
color	White to Off-White
FDA UNII	V14CN8M621

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS07
Signal word	Warning
Hazard statements	H302-H315-H319-H335
Precautionary statements	P261-P305+P351+P338

PSI-7976 price

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
TRC	S675615	Sofosbuvir(R)-Phosphate	1190308-01-0	2.5mg	$340	2021-12-16	Buy
Medical Isotopes, Inc.	67032	Sofosbuvir(R)-Phosphate	1190308-01-0	2.5mg	$650	2021-12-16	Buy
ChemScene	CS-2405	PSI-7976 98.24%	1190308-01-0	1mg	$1800	2021-12-16	Buy
ChemScene	CS-2405	PSI-7976 98.24%	1190308-01-0	5mg	$4200	2021-12-16	Buy

Product number	Packaging	Price	Buy
S675615	2.5mg	$340	Buy
67032	2.5mg	$650	Buy
CS-2405	1mg	$1800	Buy
CS-2405	5mg	$4200	Buy

PSI-7976 Chemical Properties,Uses,Production

Uses

Sofosbuvir (R)-Phosphate is an impurity of PSI-7977 (P839640), a prodrug that is metabolized to the active antiviral agent 2''-deoxy-2''-α-fluoro-β-C-methyluridine-5''-monophosphate and is currently being investigated in phase 3 clinical trials for the treatment of hepatitis C. Studies have profiled PSI-7977 as a nucleotide inhibitor of hepatitis C virus, exerting selective inhibitory effects towards HCV NS5B polymerase.

PSI-7976 Preparation Products And Raw materials

Raw materials

Preparation Products

PSI-7976 Suppliers

Global( 82)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Standardpharm Co. Ltd.	86-714-3992388	overseasales1@yongstandards.com	United States	14336	58
BOC Sciences	+1-631-485-4226	inquiry@bocsci.com	United States	19553	58
TargetMol Chemicals Inc.	+1-781-999-5354 +1-00000000000	marketing@targetmol.com	United States	19892	58
Hangzhou Huarong Pharm Co., Ltd.	571-86758373 +8613588754946	sales@huarongpharm.com	CHINA	3149	58
sgtlifesciences pvt ltd	+8617013299288	dj@sgtlifesciences.com	China	12382	58
China National Standard Pharmaceutical Corporation Limited	+8615391658522	overseasales@yongstandards.com	China	11927	58
Wuhan Topule Biopharmaceutical Co., Ltd	+8618327326525	masar@topule.com	China	8474	58
Amadis Chemical Company Limited	571-89925085	sales@amadischem.com	China	131981	58
Shanghai Payne Pharmaceutical Technology Co.Ltd	021-58123769 18678586262	info@paynepharm.com	China	1354	58
JiNan QiYuan Biotechnology Co., Ltd	18766124282	18766124282@163.COM	China	716	58

Supplier	Advantage
Standardpharm Co. Ltd.	58
BOC Sciences	58
TargetMol Chemicals Inc.	58
Hangzhou Huarong Pharm Co., Ltd.	58
sgtlifesciences pvt ltd	58
China National Standard Pharmaceutical Corporation Limited	58
Wuhan Topule Biopharmaceutical Co., Ltd	58
Amadis Chemical Company Limited	58
Shanghai Payne Pharmaceutical Technology Co.Ltd	58
JiNan QiYuan Biotechnology Co., Ltd	58

1190308-01-0(PSI-7976)Related Search:

GAMMA-CYHALOTHRIN Sofosbuvir metabolites Cytidine,N-benzoyl-2^-C-Methyl-,3^,5^-dibenzoate(9CI) PSI-7977-13C-d3 Sofosbuvir

SofosBuvir impurity 45 SofosBuvir Impurity 53 sofosBuvir Impurity 37 PSI 7411 Sofosbuvir Impurity 6

1-((2R,3S,4R,5R)-3,4-dihydroxy-5-(hydroxyMethyl)-3-Methyltetrahydrofuran-2-yl)pyriMidine-2,4(1H,3H)-dione Sofosbuvir Impurity27 SofosBuvir Impurity 38 Sofosbuvir impurity I (2R,3R,4R,5S)-5-(4-benzaMido-2-oxopyriMidin-1(2H)-yl)-2-((benzoyloxy)Methyl)-4-fluoro-4-Methyltetrahydrofuran-3-yl benzoate

Sofosbuvir impurity D SofosBuvir Impurity 31 sofosBuvir Impurity 33

1of4

PSI-7976 N-[[P(R),2'R]-2'-Deoxy-2'-fluoro-2'-methyl-P-phenyl-5'-uridylyl]-L-alanine 1-methylethyl ester Sofosbuvir (R)-Phosphate (S)-isopropyl 2-((R)-(((2R,3R,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-4-fluoro-3-hydroxy-4-methyltetrahydrofuran-2-yl)methoxy)(phenoxy)phosphorylamino)propanoate Sofosbuvir L-alanitate (Mixture of Diasteriomers)Q: What is Sofosbuvir L-alanitate (Mixture of Diasteriomers) Q: What is the CAS Number of Sofosbuvir L-alanitate (Mixture of Diasteriomers) Q: What is the storage condition of Sofosbuvir L-alanitate (Mixture of Diasteriomers) Q: What are the applications of Sofosbuvir L-alanitate (Mixture of Diasteriomers) SFB-L-Alaninate-Model Sofosbuvir phosphate salt Sofosbuvir impurity 14/ RP-Isomer of Sofosbuvir/Isopropyl ((R)-(((2R,3R,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-4-fluoro-3-hydroxy-4-methyltetrahydrofuran-2-yl)methoxy)(phenoxy)phosphoryl)-L-alaninate isopropyl ((R)-(((2R,3R,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-4-fluoro-3-hydroxy-4-methyltetrahydrofuran-2-yl)methoxy)(phenoxy)phosphoryl)-L-alanite L-Alanine, N-[[P(R),2'R]-2'-deoxy-2'-fluoro-2'-methyl-P-phenyl-5'-uridylyl]-, 1-methylethyl ester isopropyl ((R)-(((2R,3R,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-4-fluoro-3-hydroxy-4-methyltetrahydrofuran-2-yl)methoxy)(phenoxy)phosphoryl)-Lalaninate SFB-L-ALANITE-MODEL 1190308-01-0 190308-01-0