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Ethyl 4-hydroxypiperidine-1-carboxylate

CAS No.
65214-82-6
Chemical Name:
Ethyl 4-hydroxypiperidine-1-carboxylate
Synonyms
N-CARBETHOXY-4-PIPERIDINOL;ETHYL 4-HYDROXY-1-PIPERIDINECARBOXYLATE;N-Carbethoxy-4-piperidino;1-CARBETHOXY-4-PIPERIDINOL;Ethyl 4-Hydroxy-1-piperidine;N-Carboethoxypiperidine-4-Ol;Ethyl 4-hydroxypiperidine-1-;Ethyl 4-hydroxypiperidine-1-ca;1-ETHOXYCARBONYL-4-PIPERIDINOL;1-CARBETHOXY-4-HYDROXYPIPERIDINE
CBNumber:
CB4270153
Molecular Formula:
C8H15NO3
Molecular Weight:
173.21
MDL Number:
MFCD00086880
MOL File:
65214-82-6.mol
Last updated:2024-04-23 16:18:34

Ethyl 4-hydroxypiperidine-1-carboxylate Properties

Boiling point 120-130 °C(Press: 0.098 Torr)
Density 1.12
refractive index 1.4802
storage temp. Inert atmosphere,Room Temperature
form clear liquid
pka 14.80±0.20(Predicted)
color Colorless to Light yellow to Light orange
InChI InChI=1S/C8H15NO3/c1-2-12-8(11)9-5-3-7(10)4-6-9/h7,10H,2-6H2,1H3
InChIKey QABJNOSERNVHDY-UHFFFAOYSA-N
SMILES N1(C(OCC)=O)CCC(O)CC1
CAS DataBase Reference 65214-82-6(CAS DataBase Reference)
FDA UNII TR6D7H9MYK

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P271-P261-P280
Safety Statements  24/25
HS Code  29333990

Ethyl 4-hydroxypiperidine-1-carboxylate price More Price(25)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TCI Chemical E0656 Ethyl 4-Hydroxy-1-piperidinecarboxylate >98.0%(GC) 65214-82-6 5g $31 2024-03-01 Buy
TCI Chemical E0656 Ethyl 4-Hydroxy-1-piperidinecarboxylate >98.0%(GC) 65214-82-6 25g $91 2024-03-01 Buy
TRC B433603 ethyl4-hydroxypiperidine-1-carboxylate 65214-82-6 500mg $65 2021-12-16 Buy
TRC B433603 ethyl4-hydroxypiperidine-1-carboxylate 65214-82-6 100mg $45 2021-12-16 Buy
Frontier Specialty Chemicals JK320705 Ethyl 4-Hydroxy-1-piperidinecarboxylate 99% 65214-82-6 5g $46 2021-12-16 Buy
Product number Packaging Price Buy
E0656 5g $31 Buy
E0656 25g $91 Buy
B433603 500mg $65 Buy
B433603 100mg $45 Buy
JK320705 5g $46 Buy

Ethyl 4-hydroxypiperidine-1-carboxylate Chemical Properties,Uses,Production

Chemical Properties

Colorless liquid

Uses

Ethyl 4-hydroxypethidine-1-carboxylate is mainly used as a pharmaceutical intermediate and a raw material for organic matter. It can be used in the synthesis of antihistamines, antipsychotics, antidepressants, and various pesticides. As an intermediate, the compound can also produce fungicides and insecticides. It can be used as a raw material for synthetic surfactants, flavors, and fragrances.

Preparation

Add triethylamine (1.5 equivalent) and ethyl chlorine 4-hydroxypiperidine-1-carboxylate (1.2 equivalent) to the dichloromethane solution of 4-hydroxypiperidine (1.0 equivalent) at 0 °C. Stir the mixture at 0 °C for 30 min. The reaction mixture is then poured into water and extracted with methylene chloride. Wash organic extracts with water and salt water. The compound is placed on sodium sulfate to dry. Finally, the organic extract is concentrated under reduced pressure to obtainEthyl 4-hydroxypiperidine-1-carboxylate.

5382-16-1
541-41-3
65214-82-6
Synthesis of Ethyl 4-hydroxypiperidine-1-carboxylate from 4-Hydroxypiperidine and Ethyl chloroformate

Ethyl 4-hydroxypiperidine-1-carboxylate Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 291)Suppliers
Supplier Tel Email Country ProdList Advantage
Siyang Liaoning Biochemical Products Co. Ltd
+86-15221114306; +8615221114306 2594582574@qq.com China 574 58
Hebei Yanxi Chemical Co., Ltd.
+8617531190177 peter@yan-xi.com China 5993 58
Henan Bao Enluo International TradeCo.,LTD
+86-17331933971 +86-17331933971 deasea125996@gmail.com China 2503 58
Anhui Zhongda Biotechnology Co., Ltd
+8619956560829 justine@zhongda-biotech.com China 300 58
Anhui Ruihan Technology Co., Ltd
+8617756083858 daisy@anhuiruihan.com China 994 58
hebei hongtan Biotechnology Co., Ltd
+86-86-1913198-3935 +8617331935328 sales03@chemcn.cn China 951 58
Ouhuang Engineering Materials (Hubei) Co., Ltd
+8617702722807 admin@hbouhuang.com China 2259 58
Capot Chemical Co.,Ltd.
571-85586718 +8613336195806 sales@capotchem.com China 29797 60
Beijing Cooperate Pharmaceutical Co.,Ltd
010-60279497 sales01@cooperate-pharm.com CHINA 1811 55
Shanghai Bojing Chemical Co.,Ltd.
+86-86-02137122233 +8613795318958 bj1@bj-chem.com China 298 55

View Lastest Price from Ethyl 4-hydroxypiperidine-1-carboxylate manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Ethyl 4-hydroxypiperidine-1-carboxylate  pictures 2024-04-26 Ethyl 4-hydroxypiperidine-1-carboxylate
65214-82-6
US $50.00 / kg 1kg 99% 2000kg hebei hongtan Biotechnology Co., Ltd
N-Carbethoxy-4-Hydroxy Piperidine pictures 2024-04-23 N-Carbethoxy-4-Hydroxy Piperidine
65214-82-6
US $100.00-30.00 / kg 1kg 99.93% 1000kg per week Ouhuang Engineering Materials (Hubei) Co., Ltd
N-Carbethoxy-4-hydroxypiperidine pictures 2024-03-21 N-Carbethoxy-4-hydroxypiperidine
65214-82-6
US $90.00-80.00 / kg 1kg 99% 2000kgs Hebei Yanxi Chemical Co., Ltd.
Ethyl 4-hydroxy-N-piperidinecarboxylate 1-Ethoxycarbonyl-1-piperidinol, 98% Ethyl 4-hydroxypiperidine-1-ca 1-(Ethoxycarbonyl)-4-hydroxypiperidine Ethyl 4-Hydroxy-1-piperidine 1-Carbethoxy-4-hydroxypiperidine 4-Hydroxy-1-piperidinecarboxylic Acid Ethyl Ester 1-PIPERIDINECARBOXYLIC ACID, 4-HYDROXY-, ETHYL ESTER 1-ETHOXYCARBONYL-4-PIPERIDINOL 1-CARBETHOXY-4-HYDROXYPIPERIDINE 1-CARBETHOXY-4-PIPERIDINOL ETHYL 4-HYDROXYPIPERIDINE-1-CARBOXYLATE N-CARBETHOXY-4-HYDROXYPIPERIDINE 4-HYDROXY-1-PIPERIDINECARBOXYLIC ACID ETHYL ESTER 4-HYDROXY-PIPERIDINE-1-CARBOXYLIC ACID ETHYL ESTER 1-(Ethoxycarbonyl)piperidin-4-ol N-Carboethoxypiperidine-4-Ol N-carbethoxy-4-piperidinemethanol Ethyl 4-hydroxypiperidine-1- Ethyl4-Hydroxy-1-piperidinecarboxylate> Ethyl ester, 4-hydroxypiperidine-1-carboxylate Ethyl 4-hydroxycyclopiperidine-1- carboxylate Ethyl4-hydroxypiperidine-1- carboxylate(4-HNCP) N-ethoxycarbonyl-4-hydroxypiperidine N-carbethoxy-4-hydroxypiperidone. Ethyl 4-hydroxypiperidine-1-caroxylate ETHYL 4-HYDROXY-1-PIPERIDINECARBOXYLATE N-CARBETHOXY-4-PIPERIDINOL N-Carbethoxy-4-piperidino N-Carbethoxy-4-hydroxy Piperdine 4-hydroxypiperidin-1-ethyl formate 65214-82-6 65214-8-6 Piperidine