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para-Hydroxy Atorvastatin CalciuM Salt

para-Hydroxy Atorvastatin CalciuM Salt Structure
para-Hydroxy Atorvastatin CalciuM Salt structure
CAS No.
265989-44-4
Chemical Name:
para-Hydroxy Atorvastatin CalciuM Salt
Synonyms
Amlodipine Impurity 88;4-Hydroxy Atorvastatin;Atorvastatin Impurity J;Atorvastatin Impurity 52;Atorvastatin Impurity 154;Para-Hydroxy Atorvastatin Calcium;4-Hydroxy Atorvastatin HeMicalciuM Salt;calcium,(3S,5S)-7-[2-(4-fluorophenyl)-4-[(4-hydroxyphenyl)carbamoyl]-3-phenyl-5-propan-2-ylpyrrol-1-yl]-3,5-dihydroxyheptanoate;Atorvastatin impurity 35/para-Hydroxy Atorvastatin Calcium Salt/(3R,5R)-7-[2-(4-fluorophenyl)-4-[(4-hydroxyphenyl)carbamoyl]-3-phenyl-5-propan-2-ylpyrrol-1-yl]-3,5-dihydroxyheptanoate Calcium Salt;4-Hydroxy-Atorvastatin calcium saltQ: What is 4-Hydroxy-Atorvastatin calcium salt Q: What is the CAS Number of 4-Hydroxy-Atorvastatin calcium salt Q: What is the storage condition of 4-Hydroxy-Atorvastatin calcium salt Q: What are the applications of 4-Hydroxy-Atorvastatin calcium salt
CBNumber:
CB42707055
Molecular Formula:
C66H70CaF2N4O12
Molecular Weight:
1189.3564064
MDL Number:
MOL File:
265989-44-4.mol
Last updated:2023-06-08 09:02:51
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para-Hydroxy Atorvastatin CalciuM Salt Properties

storage temp. Store at -20°C
solubility DMF: 25 mg/ml; DMF:PBS (pH 7.2) (1:9): 0.1 mg/ml; DMSO: 15 mg/ml; Ethanol: 0.5 mg/ml
form A crystalline solid

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H302
Precautionary statements  P264-P270-P301+P312-P330-P501
NFPA 704
0
2 0

para-Hydroxy Atorvastatin CalciuM Salt price More Price(4)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Cayman Chemical 22575 4-hydroxy Atorvastatin (calcium salt) ≥90% 265989-44-4 500μg $81 2024-03-01 Buy
Cayman Chemical 22575 4-hydroxy Atorvastatin (calcium salt) ≥90% 265989-44-4 1mg $152 2024-03-01 Buy
Cayman Chemical 22575 4-hydroxy Atorvastatin (calcium salt) ≥90% 265989-44-4 5mg $515 2024-03-01 Buy
Medical Isotopes, Inc. 4857 p-Hydroxyatorvastatincalciumsalt 98% 265989-44-4 1mg $590 2021-12-16 Buy
Product number Packaging Price Buy
22575 500μg $81 Buy
22575 1mg $152 Buy
22575 5mg $515 Buy
4857 1mg $590 Buy

para-Hydroxy Atorvastatin CalciuM Salt Chemical Properties,Uses,Production

Description

4-hydroxy Atorvastatin is a metabolite of atorvastatin , an HMG-CoA reductase inhibitor present in formulations that have been used to treat hypercholesterolemia and certain dyslipidemias.1,2,3,4 Atorvastatin is metabolized by the cytochrome P450 (CYP) isoform CYP3A4 to form 4-hydroxy atorvastatin.1

References

1. Hong, J.H., Youm, J.K., Kwon, M.J., et al. K6PC-5, a direct activator of sphingosine kinase 1, promotes epidermal differentiation through intracellular Ca2+ signaling J. Invest. Dermatol. 128,2166-2178(2008).
2. Dart, A., Jerums, G., Nicholson, G., et al. A multicenter, double-blind, one-year study comparing safety and efficacy of atorvastatin versus simvastatin in patients with hypercholesterolemia Am. J. Cardiol. 80(1),39-44(1997).
3. Group, T.D.A.L.I.S. The effect of aggressive versus standard lipid lowering by atorvastatin on diabetic dyslipidemia. The DALI study: A double-blind, randomized, placebo-controlled trial in patients with type 2 diabetes and diabetic dyslipidemia Diabetes Care 24(8),1335-1341(2001).
4. van Dam, M., Zwart, M., de Beer, F., et al. Long term efficacy and safety of atorvastatin in the treatment of severe type III and combined dyslipidaemia Heart 88(3),234-238(2002).

para-Hydroxy Atorvastatin CalciuM Salt Preparation Products And Raw materials

Raw materials

Preparation Products

para-Hydroxy Atorvastatin CalciuM Salt Suppliers

Global( 46)Suppliers
Supplier Tel Email Country ProdList Advantage
Standardpharm Co. Ltd. 		86-714-3992388 overseasales1@yongstandards.com United States 14336 58
Finetech Industry Limited 		+86-27-87465837 +8618971612321 info@finetechnology-ind.com China 9702 58
Hangzhou Huarong Pharm Co., Ltd. 		571-86758373 +8613588754946 sales@huarongpharm.com CHINA 3149 58
sgtlifesciences pvt ltd 		+8617013299288 dj@sgtlifesciences.com China 12382 58
J & K SCIENTIFIC LTD. 010-82848833 400-666-7788 jkinfo@jkchemical.com China 96815 76
Chemsky（shanghai）International Co.,Ltd. 021-50135380 shchemsky@sina.com China 32344 50
BOC Sciences 1-631-485-4226; 16314854226 info@bocsci.com United States 14059 65
Cato Research Chemicals Inc. 020-81960175 min.he@cato-chem.com China 1958 55
ChemStrong Scientific Co.,Ltd 0755-66853366 13670046396 sales@chem-strong.com China 17982 56
Finetech Industry Limited 027-87465837 19945049750 sales@finetechnology-ind.com China 9664 58
Supplier Advantage
Standardpharm Co. Ltd. 		58
Finetech Industry Limited 		58
Hangzhou Huarong Pharm Co., Ltd. 		58
sgtlifesciences pvt ltd 		58
J & K SCIENTIFIC LTD. 76
Chemsky（shanghai）International Co.,Ltd. 50
BOC Sciences 65
Cato Research Chemicals Inc. 55
ChemStrong Scientific Co.,Ltd 56
Finetech Industry Limited 58

View Lastest Price from para-Hydroxy Atorvastatin CalciuM Salt manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Para-Hydroxy Atorvastatin Calcium Salt pictures 2021-09-18 Para-Hydroxy Atorvastatin Calcium Salt
265989-44-4
 US $0.00-0.00 / mg 10mg 99% 10KG Hangzhou Huarong Pharm Co., Ltd.

265989-44-4(para-Hydroxy Atorvastatin CalciuM Salt)Related Search:

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Ortho-Hydroxy atorvastatin calcium salt 4-Hydroxy Atorvastatin Lactone-d5 para-Hydroxy Atorvastatin-d5 CalciuM Salt Dihydroxy Diketo Atorvastatin IMpurity 5-Oxo Atorvastatin tert-Butyl Ester
Atorvastatin Impurity 46 Atorvastatin Impurity 38 Atorvastatin 3-Oxo Atorvastatin tert-Butyl Ester Atorvastatin Impurity 15
2-[1,2-Bis-(4-fluoro-phenyl)-2-oxo-ethyl]-4-methyl-3-oxo-pentanoic acid phenylamide Atorvastatin Dehydro Lactone Atorvastatin Impurity 20

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4-Hydroxy Atorvastatin HeMicalciuM Salt 4-Hydroxy Atorvastatin Atorvastatin impurity 35/para-Hydroxy Atorvastatin Calcium Salt/(3R,5R)-7-[2-(4-fluorophenyl)-4-[(4-hydroxyphenyl)carbamoyl]-3-phenyl-5-propan-2-ylpyrrol-1-yl]-3,5-dihydroxyheptanoate Calcium Salt Atorvastatin Impurity 52 Atorvastatin Impurity J Para-Hydroxy Atorvastatin Calcium Atorvastatin Impurity 154 calcium,(3S,5S)-7-[2-(4-fluorophenyl)-4-[(4-hydroxyphenyl)carbamoyl]-3-phenyl-5-propan-2-ylpyrrol-1-yl]-3,5-dihydroxyheptanoate 4-Hydroxy-Atorvastatin calcium saltQ: What is 4-Hydroxy-Atorvastatin calcium salt Q: What is the CAS Number of 4-Hydroxy-Atorvastatin calcium salt Q: What is the storage condition of 4-Hydroxy-Atorvastatin calcium salt Q: What are the applications of 4-Hydroxy-Atorvastatin calcium salt Amlodipine Impurity 88 265989-44-4