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11-Hexadecenoic acid, 16-[[(ethylaMino)carbonyl]aMino]-, (11Z)-

11-Hexadecenoic acid, 16-[[(ethylaMino)carbonyl]aMino]-, (11Z)- structure

CAS No.: 1184844-74-3

Chemical Name:: 11-Hexadecenoic acid, 16-[[(ethylaMino)carbonyl]aMino]-, (11Z)-

Synonyms: CAY10662;CAY10662 Exclusive;OUFBVXMGWWCVFO-CLFYSBASSA-N;11-Hexadecenoic acid, 16-[[(ethylaMino)carbonyl]aMino]-, (11Z)-

CBNumber:: CB42715322

Molecular Formula:: C19H36N2O3

Molecular Weight:: 340.5

MDL Number:

MOL File:: 1184844-74-3.mol

Last updated:2023-07-09 08:28:05

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11-Hexadecenoic acid, 16-[[(ethylaMino)carbonyl]aMino]-, (11Z)- Properties

Melting point	83.1-83.3 °C
Boiling point	546.9±33.0 °C(Predicted)
Density	0.986±0.06 g/cm3(Predicted)
storage temp.	Store at -20°C
solubility	DMF: 5 mg/ml; DMF:PBS (pH 7.2) (1:4): 0.2 mg/ml; DMSO: 3 mg/ml; Ethanol: 2 mg/ml
pka	4.78±0.10(Predicted)

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS02,GHS06

Signal word

Danger

NFPA 704

	3
0		0

11-Hexadecenoic acid, 16-[[(ethylaMino)carbonyl]aMino]-, (11Z)- price More Price(4)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Cayman Chemical	11042	CAY10662 ≥98%	1184844-74-3	25μg	$48	2024-03-01	Buy
Cayman Chemical	11042	CAY10662 ≥98%	1184844-74-3	50μg	$89	2024-03-01	Buy
Cayman Chemical	11042	CAY10662 ≥98%	1184844-74-3	100μg	$168	2024-03-01	Buy
Cayman Chemical	11042	CAY10662 ≥98%	1184844-74-3	500μg	$739	2024-03-01	Buy

Product number	Packaging	Price	Buy
11042	25μg	$48	Buy
11042	50μg	$89	Buy
11042	100μg	$168	Buy
11042	500μg	$739	Buy

11-Hexadecenoic acid, 16-[[(ethylaMino)carbonyl]aMino]-, (11Z)- Chemical Properties,Uses,Production

Description

17(R),18(S)-Epoxyeicosatetraenoic acid (17(R),18(S)-EpETE), a natural cytochrome P450 epoxygenase metabolite of eicosapentaenoic acid, is known to reduce the contraction rate of spontaneously beating heart cells and to protect neonatal rat cardiomyocytes against arrhythmias induced by β-adrenergic agonists (EC₅₀ = ~ 1-2 nM).¹ CAY10662 is a 1,3 disubstituted urea derivative of 17(R),18(S)-EpETE that is more metabolically robust and reduces the contractility of cardiomyocytes with improved potency (EC₅₀ < 1 nM) over its parent compound.¹ At concentrations 1,000-fold higher than required for the effect on cardiomyocytes, 1-5 μM CAY10662 exerts weak dose-dependent soluble epoxide hydrolase inhibition.¹

References

1. Falck, J.R., Wallukat, G., Puli, N., et al. 17(R),18(S)-Epoxyeicosatetraenoic acid, a potent eicosapentaenoic acid (EPA) derived regulator of cardiomyocyte contraction: Structure-activity relationships and stable analogues J. Med. Chem. 54(12),4109-4118(2011).

11-Hexadecenoic acid, 16-[[(ethylaMino)carbonyl]aMino]-, (11Z)- synthesis

Synthesis of 11-Hexadecenoic acid, 16-[[(ethylaMino)carbonyl]aMino]-, (11Z)- from Methyl (11Z)-16-[[(ethylamino)carbonyl]amino]-11-hexadecenoate

11-Hexadecenoic acid, 16-[[(ethylaMino)carbonyl]aMino]-, (11Z)- Preparation Products And Raw materials

Raw materials

Preparation Products

11-Hexadecenoic acid, 16-[[(ethylaMino)carbonyl]aMino]-, (11Z)- Suppliers

Global( 14)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Shanghai Yifei Biotechnology Co. , Ltd.	021-65675885 18964387627	customer_service@efebio.com	China	8740	58

Supplier	Advantage
Shanghai Yifei Biotechnology Co. , Ltd.	58

11-Hexadecenoic acid, 16-[[(ethylaMino)carbonyl]aMino]-, (11Z)- CAY10662 CAY10662 Exclusive OUFBVXMGWWCVFO-CLFYSBASSA-N 1184844-74-3