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SELEXIPAG interMediate

CAS No.
475086-75-0
Chemical Name:
SELEXIPAG interMediate
Synonyms
4-[(5,6-diphenyl-2-pyrazinyl)(1-methylethyl)amino]-1-Butanol;SELEXIPAH INT;Selexipag Impurity 32;Selexipag internate 1;SELEXIPAG interMediate;Selexipag intermediates;Diphenyl pyrazine impurity;4-((5,6-Diphenylpyrazin-2-yl)(isopropyl)amino)butan-1-ol;4-[(5,6-Diphenylpyrazinyl)(1-methylethyl)amino]-1-butanol;-[(5,6-diphenyl-2-pyrazinyl)(1-methylethyl)amino]-1-Butanol
CBNumber:
CB42728841
Molecular Formula:
C23H27N3O
Molecular Weight:
361.48
MDL Number:
MFCD28411750
MOL File:
475086-75-0.mol
MSDS File:
SDS
Last updated:2024-03-22 21:24:34

SELEXIPAG interMediate Properties

Melting point 68 - 71°C
Boiling point 514.4±50.0 °C(Predicted)
Density 1.112±0.06 g/cm3(Predicted)
storage temp. Sealed in dry,Room Temperature
solubility Chloroform (Slightly), DMSO (Slightly)
pka 15.05±0.10(Predicted)
form Solid
color Pale Yellow to Light Yellow

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P261-P280-P301+P312-P302+P352-P305+P351+P338

SELEXIPAG interMediate price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
ChemScene CS-M3070 1-Butanol,4-[(5,6-diphenylpyrazinyl)(1-methylethyl)amino]- 475086-75-0 1g $100 2021-12-16 Buy
Ambeed A822980 4-((5,6-Diphenylpyrazin-2-yl)(isopropyl)amino)butan-1-ol 98% 475086-75-0 1g $112 2021-12-16 Buy
Chemenu CM101916 4-[(5,6-Diphenylpyrazinyl)(1-methylethyl)amino]-1-butanol 95%+ 475086-75-0 1g $182 2021-12-16 Buy
Crysdot CD11120258 4-((5,6-Diphenylpyrazin-2-yl)(isopropyl)amino)butan-1-ol 97% 475086-75-0 1g $200 2021-12-16 Buy
Ambeed A822980 4-((5,6-Diphenylpyrazin-2-yl)(isopropyl)amino)butan-1-ol 98% 475086-75-0 5g $311 2021-12-16 Buy
Product number Packaging Price Buy
CS-M3070 1g $100 Buy
A822980 1g $112 Buy
CM101916 1g $182 Buy
CD11120258 1g $200 Buy
A822980 5g $311 Buy

SELEXIPAG interMediate Chemical Properties,Uses,Production

Uses

4-[(5,6-Diphenyl-2-pyrazinyl)(1-methylethyl)amino]-1-butanol is a diphenylpyrazine derivative which belongs to a class of prostacyclin receptor agonists. It is an impurity of Selexipag (S253150) that is a potential drug for the treatment of various vascular disorders such as pulmonary arterial hypertension and arteriosclerosis obliterans.

Application

Selexipag interMediate is a synthetic organic compound that is used as an intermediate in the synthesis of oxychloride. It is an oxychloride with a nucleophilic substitution reaction. The reaction proceeds selectively at the phosphorus atom and gives high yield. The reactivity of 4-[(5,6-diphenylpyrazin-2-yl)(propan-2-yl)amino]butan-1-ol is enhanced by the use of n butanol, which also acts as a solvent for the reaction. The product can be purified by filtration or recrystallization from hexane with piperazine as a reagent.

41270-66-0
42042-71-7
475086-75-0
Synthesis of SELEXIPAG interMediate from 5-chloro-2,3-diphenylpyrazine and 4-(Isopropylamino)butanol

SELEXIPAG interMediate Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 113)Suppliers
Supplier Tel Email Country ProdList Advantage
Seasons Biotechnology Co., Ltd.
+86-0576-89232655 +86-13566878689 info@seasonsbio.com China 46 58
Henan Fengda Chemical Co., Ltd
+86-371-86557731 +86-13613820652 info@fdachem.com China 7377 58
Capot Chemical Co.,Ltd.
571-85586718 +8613336195806 sales@capotchem.com China 29797 60
Shanghai Daken Advanced Materials Co.,Ltd
+86-371-66670886 info@dakenam.com China 15371 58
Beijing Cooperate Pharmaceutical Co.,Ltd
010-60279497 sales01@cooperate-pharm.com CHINA 1811 55
Henan Tianfu Chemical Co.,Ltd.
+86-0371-55170693 +86-19937530512 info@tianfuchem.com China 21695 55
career henan chemical co
+86-0371-86658258 sales@coreychem.com China 29914 58
Chongqing Chemdad Co., Ltd
+86-023-61398051 +8613650506873 sales@chemdad.com China 39916 58
Shenzhen Excellent Biotech Co., Ltd.
13480692018 ramyan@ex-biotech.com CHINA 954 58
Shanghai Yingrui Biopharma Co.,Ltd
21-33585366 export01@shyrchem.com CHINA 1320 58

View Lastest Price from SELEXIPAG interMediate manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
SELEXIPAG interMediate pictures 2024-03-23 SELEXIPAG interMediate
475086-75-0
US $35.00-0.90 / kg 1kg 99% g-kg-tons, free sample is available Henan Fengda Chemical Co., Ltd
SELEXIPAG interMediate pictures 2019-07-06 SELEXIPAG interMediate
475086-75-0
US $2.00 / KG 1KG 98% 200KG Career Henan Chemical Co
SELEXIPAG interMediate Selexipag intermediates 1-Butanol, 4-[(5,6-diphenylpyrazinyl)(1-methylethyl)amino]- 1-Butanol, 4-[(5,6-diphenyl-2-pyrazinyl)(1-methylethyl)amino]- 4-[(5,6-Diphenylpyrazinyl)(1-methylethyl)amino]-1-butanol -[(5,6-diphenyl-2-pyrazinyl)(1-methylethyl)amino]-1-Butanol Selexipag Impurity AQ: What is Selexipag Impurity A Q: What is the CAS Number of Selexipag Impurity A Q: What is the storage condition of Selexipag Impurity A Q: What are the applications of Selexipag Impurity A Selexipag internate 1 SELEXIPAH INT Selexipag Impurity 32 4-((5,6-Diphenylpyrazin-2-yl)(isopropyl)amino)butan-1-ol 4-[(5,6-diphenyl-2-pyrazinyl)(1-methylethyl)amino]-1-Butanol Diphenyl pyrazine impurity 4-((5,6-Diphenylpyrazin-2-yl)(isopropyl)amino)butan-1-ol (Isopropylamine Impurity) 475086-75-0 non-prostanoid prostacyclin (PGI2) receptor agonist selexipag