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USP7-IN-1

USP7-IN-1 Structure
USP7-IN-1 structure
CAS No.
1381291-36-6
Chemical Name:
USP7-IN-1
Synonyms
USP7i-1;USP7-IN-1;USP7 inhibitor 1;Inhibitor,inhibit,USP-7-IN-1,USP7IN1,USP7 IN 1,DUBs,Deubiquitinase;4(3H)-Quinazolinone, 7-chloro-3-[[4-hydroxy-1-(1-oxo-3-phenylpropyl)-4-piperidinyl]methyl]-
CBNumber:
CB42729378
Molecular Formula:
C23H24ClN3O3
Molecular Weight:
425.91
MDL Number:
MOL File:
1381291-36-6.mol
MSDS File:
SDS
Last updated:2023-09-04 15:50:00
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USP7-IN-1 Properties

Boiling point 666.2±65.0 °C(Predicted)
Density 1.32±0.1 g/cm3(Predicted)
storage temp. Store at -20°C
solubility DMSO: ≥ 40 mg/mL (93.92 mM)
pka 13.52±0.20(Predicted)

USP7-IN-1 price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
ChemScene CS-3515 USP7-IN-1 98.92% 1381291-36-6 5mg $420 2021-12-16 Buy
ChemScene CS-3515 USP7-IN-1 98.92% 1381291-36-6 10mg $600 2021-12-16 Buy
ChemScene CS-3515 USP7-IN-1 98.92% 1381291-36-6 50mg $1800 2021-12-16 Buy
ChemScene CS-3515 USP7-IN-1 98.92% 1381291-36-6 100mg $2520 2021-12-16 Buy
Crysdot CD31003679 USP7-IN-1 98+% 1381291-36-6 5mg $243 2021-12-16 Buy
Product number Packaging Price Buy
CS-3515 5mg $420 Buy
CS-3515 10mg $600 Buy
CS-3515 50mg $1800 Buy
CS-3515 100mg $2520 Buy
CD31003679 5mg $243 Buy

USP7-IN-1 Chemical Properties,Uses,Production

Description

USP7-IN-1 is a selective and reversible inhibitor of ubiquitin-specific protease 7 (USP7), with an IC50 of 77 μM, and can be used for the research of cancer. IC50: 77 μM (USP7)[1]

USP7-IN-1 (Example 2) is a selective and reversible inhibitor of USP7, with an IC50 of 77 μM, and shows no inhibition of USP8, USP5, Uch-L1, Uch-L3 or caspase 3. USP7-IN-1 inhibits the proliferation of HCT116 cells, with a GI50 of 67 μM[1].

References

[1]. SELECTIVE AND REVERSIBLE INHIBITORS OF UBIQUITIN SPECIFIC PROTEASE 7. WO 2013030218 A1

USP7-IN-1 synthesis

1426340-66-0
501-52-0
1381291-36-6
Synthesis of USP7-IN-1 from Ethanamine, N-[(3,5-dichlorophenyl)methylene]-2,2-diethoxy- and 3-Phenylpropionic acid

USP7-IN-1 Preparation Products And Raw materials

Raw materials

2-Amino-4-chlorobenzoic acid 7-CHLORO-4-QUINAZOLINOL 3-Phenylpropionic acid

Preparation Products

USP7-IN-1 Suppliers

Global( 28)Suppliers
Supplier Tel Email Country ProdList Advantage
TargetMol Chemicals Inc. 		+1-781-999-5354 +1-00000000000 marketing@targetmol.com United States 19892 58
HANGZHOU CLAP TECHNOLOGY CO.,LTD 		86-571-88216897,88216896 13588875226 sales@hzclap.com CHINA 6313 58
Amadis Chemical Company Limited 		571-89925085 sales@amadischem.com China 131981 58
Haoyuan Chemexpress Co., Ltd. 021-58950125 info@chemexpress.com China 7553 61
MedChemexpress LLC 021-58955995 sales@medchemexpress.cn United States 4863 58
Sichuan Wei Keqi Biological Technology Co., Ltd. 028-81700200 18116577057 3003855609@qq.com China 7892 56
LETOPHARM LIMITED +86-21-5821 5861 sales@letopharm.com China 2384 58
Birdo (Shanghai) Medical Technology Co., Ltd. 021-58099077 sales@birdochem.com China 185 55
Shanghai Beckham Medical Technology Co., Ltd 021-13816613772 13816613772 huahero21@sina.com China 357 55
Guangzhou QiYun Biotechnology Co., Ltd. 020-61288194 61288195 505721671@qq.com China 3868 58
Supplier Advantage
TargetMol Chemicals Inc. 		58
HANGZHOU CLAP TECHNOLOGY CO.,LTD 		58
Amadis Chemical Company Limited 		58
Haoyuan Chemexpress Co., Ltd. 61
MedChemexpress LLC 58
Sichuan Wei Keqi Biological Technology Co., Ltd. 56
LETOPHARM LIMITED 58
Birdo (Shanghai) Medical Technology Co., Ltd. 55
Shanghai Beckham Medical Technology Co., Ltd 55
Guangzhou QiYun Biotechnology Co., Ltd. 58

USP7-IN-1 Spectrum

USP7-IN-1(1381291-36-6)1HNMR
USP7-IN-1 4(3H)-Quinazolinone, 7-chloro-3-[[4-hydroxy-1-(1-oxo-3-phenylpropyl)-4-piperidinyl]methyl]- USP7i-1 USP7 inhibitor 1 Inhibitor,inhibit,USP-7-IN-1,USP7IN1,USP7 IN 1,DUBs,Deubiquitinase 1381291-36-6