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Sofosbuvir metabolites GS566500

CAS No.
1233335-78-8
Chemical Name:
Sofosbuvir metabolites GS566500
Synonyms
GS-566500;PSI 352707;Sofosbuvir metabolites GS566500;Sofosbuvir Impurity 49 (GS-566500);SofosbuvirImpurity49Di-TriethylamineSalt;Sofosbuvir O-Desisopropyl O-Desphenyl Impurity;O-Desisopropyl O-Desphenyl Sofosbuvir Ammonium Salt;N-[(2'R)-2'-Deoxy-2'-fluoro-2'-methyl-5'-uridylyl]-L-alanine;L-Alanine, N-[(2'R)-2'-deoxy-2'-fluoro-2'-methyl-5'-uridylyl]-;((((2R,3R,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-4-fluoro-3-hydroxy-4-methyltetrahydrofuran-2-yl)met hoxy)(hydroxy)phosphoryl)-L-alanine
CBNumber:
CB42744900
Molecular Formula:
C13H19FN3O9P
Molecular Weight:
411.28
MDL Number:
MFCD28964036
MOL File:
1233335-78-8.mol
MSDS File:
SDS
Last updated:2023-07-07 08:28:07

Sofosbuvir metabolites GS566500 Properties

Density 1?+-.0.1 g/cm3(Predicted)
solubility DMSO (Slightly), Methanol (Very Slightly, Heated)
form Solid
pka 2.66±0.50(Predicted)
color Off-White to Pale Beige
FDA UNII 8C9Y1F217H

Sofosbuvir metabolites GS566500 price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Medical Isotopes, Inc. 52861 PSI352707 1233335-78-8 1mg $650 2021-12-16 Buy
Product number Packaging Price Buy
52861 1mg $650 Buy

Sofosbuvir metabolites GS566500 Chemical Properties,Uses,Production

Uses

PSI 352707 Ammonium Salt is a metabolite of PSI-7977 (P839640), a prodrug that is metabolized to the active antiviral agent 2'-deoxy-2'-a-fluoro-b-C-methyluridine-5'-monophosphate and is currently being investigated in phase 3 clinical trials for the treatment of hepatitis C.

1064684-44-1
1233335-78-8
Synthesis of Sofosbuvir metabolites GS566500 from PSI 7851

Sofosbuvir metabolites GS566500 Preparation Products And Raw materials

Raw materials

Preparation Products

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Sofosbuvir metabolites GS566500 GS-566500 N-[(2'R)-2'-Deoxy-2'-fluoro-2'-methyl-5'-uridylyl]-L-alanine (2S)-2-(((((2R,3R,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-4-fluoro-3-hydroxy-4-methyltetrahydrofuran-2-yl)methoxy)(hydroxy)phosphoryl)amino)propanoic acid PSI 352707 Sofosbuvir Impurity 49 (GS-566500) (2S)-2-(((((2R,3R,4R,5R)-5-(2,4-Dioxo-3,4-dihydropyrimidin-1(2H)-yl)-4-fluoro-3-hydroxy-4-methyltetrahydrofuran-2-yl)methoxy)(hydroxy)phosphoryl)amino)propanoic Acid Ammonium Salt O-Desisopropyl O-Desphenyl Sofosbuvir Ammonium Salt (2S)-2-(((((2R,3R,4R,5S)-5-((R)-2,6-dioxo-1,2,3,6-tetrahydropyridin-3-yl)-4-fluoro-3-hydroxy-4-methyltetrahydrofuran-2-yl)methoxy)(hydroxy)phosphoryl)amino)propanoic acid Sofosbuvir O-Desisopropyl O-Desphenyl Impurity Sofosbuvir impurity 10/((((2R,3R,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-4-fluoro-3-hydroxy-4-methyltetrahydrofuran-2-yl)methoxy)(hydroxy)phosphoryl)-L-alanine Sofosbuvir metabolite GS-566500Q: What is Sofosbuvir metabolite GS-566500 Q: What is the CAS Number of Sofosbuvir metabolite GS-566500 Q: What is the storage condition of Sofosbuvir metabolite GS-566500 SofosbuvirImpurity49Di-TriethylamineSalt (S)-2-(((S)-(((2R,3R,4R,5R)-5-(2,4-Dioxo-3,4-dihydropyrimidin-1(2H)-yl)-4-fluoro-3-hydroxy-4-methyltetrahydrofuran-2-yl)methoxy)(hydroxy)phosphoryl)amino)propanoic acid (Sofosbuvir Impurity) ((((2R,3R,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-4-fluoro-3-hydroxy-4-methyltetrahydrofuran-2-yl)met hoxy)(hydroxy)phosphoryl)-L-alanine L-Alanine, N-[(2'R)-2'-deoxy-2'-fluoro-2'-methyl-5'-uridylyl]- 1233335-78-8 C13H19FN3O9P