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Tygacil

CAS No.
1229002-07-6
Chemical Name:
Tygacil
Synonyms
TBG-MINO;Tigecyclin;GAR-936 hydrate;Tigecycline hydrate;9-t-Butylglycylamido-minocycline hydrate;(4S,4aS,5aR,12aR)-9-[[2-(tert-butylamino)acetyl]amino]-4,7-bis(dimethylamino)-1,10,11,12a-tetrahydroxy-3,12-dioxo-4a,5,5a,6-tetrahydro-4H-tetracene-2-carboxamide,hydrate
CBNumber:
CB42750374
Molecular Formula:
C29H41N5O9
Molecular Weight:
603.67
MDL Number:
MOL File:
1229002-07-6.mol
Last updated:2023-04-23 13:52:06

Tygacil Properties

storage temp. 2-8°C
solubility DMSO: ≥3mg/mL (warmed)
form powder
color off-white to yellow-brown
optical activity [α]/D -160 to 170°, c = 0.15 in methanol

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictogramsGHS hazard pictograms
GHS07,GHS08
Signal word  Danger
Hazard statements  H319-H360
Precautionary statements  P202-P264-P280-P305+P351+P338-P308+P313-P337+P313
Hazard Codes  Xi
Risk Statements  61-36-52-64
Safety Statements  13-36/37/39
WGK Germany  3
RTECS  QI7619500

Tygacil price More Price(3)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich PZ0021 Tigecycline hydrate ≥98% (HPLC) 1229002-07-6 5mg $119 2024-03-01 Buy
Sigma-Aldrich PZ0021 Tigecycline hydrate ≥98% (HPLC) 1229002-07-6 25mg $483 2024-03-01 Buy
TRC T440038 Tigecycline hydrate 1229002-07-6 2mg $60 2021-12-16 Buy
Product number Packaging Price Buy
PZ0021 5mg $119 Buy
PZ0021 25mg $483 Buy
T440038 2mg $60 Buy

Tygacil Chemical Properties,Uses,Production

Uses

Tigecycline hydrate, a glycylcycline antibiotic, used to treat infection by drug resistant bacteria such as Staphylococcus aureus (Staph aureus) and Acinetobacter baumannii.

General Description

Tigecycline is used to treat complicated skin and skin structure infections (cSSSI) and complicated intraabdominal infections.

Biochem/physiol Actions

Tigecycline is a broad spectrum glycylcycline antibiotic. Tigecycline is bacteriostatic, that inhibits protein synthesis by binding to the 30S ribosomal subunit of bacteria and thereby blocking entry of Aminoacyl-tRNA into the A site of the ribosome during prokaryotic translation. Tigecycline is active against resistant strains of gram-positive and gram-negative bacteria, avoiding the two most common mechanisms of resistance to the tetracycline antimicrobials: tetracycline efflux pump proteins and ribosomal protection proteins.

Tygacil Preparation Products And Raw materials

Raw materials

Preparation Products

Tygacil Suppliers

Global( 8)Suppliers
Supplier Tel Email Country ProdList Advantage
Hunan Hui Bai Shi Biotechnology Co., Ltd. 0731-85526065 13308475853 ivy@hnhbsj.com China 4548 62
Sigma-Aldrich 021-61415566 800-8193336 orderCN@merckgroup.com China 51471 80
Beijing Jin Ming Biotechnology Co., Ltd. 010-60605840 18892239720 psaitong@jm-bio.com China 12308 58
DC Chemicals 021-58447131 13564518121 sales@dcchemicals.com China 9414 58
Shanghai Sunway Pharmaceutical Technology Co.,Ltd. 021-51816796-820 13611835272 sales2@sunwaypharm.com China 44498 58
Beijing Jin Ming Biotechnology Co., Ltd. 010-60605840 15801484223 psaitong@jm-bio.com China 29834 58
9-t-Butylglycylamido-minocycline hydrate TBG-MINO Tigecyclin Tigecycline hydrate GAR-936 hydrate (4S,4aS,5aR,12aR)-9-[[2-(tert-butylamino)acetyl]amino]-4,7-bis(dimethylamino)-1,10,11,12a-tetrahydroxy-3,12-dioxo-4a,5,5a,6-tetrahydro-4H-tetracene-2-carboxamide,hydrate 1229002-07-6