ChemicalBook >> CAS DataBase List >>Coumarin 151
Coumarin 151
- CAS No.
- 53518-15-3
- Chemical Name:
- Coumarin 151
- Synonyms
- AFC;7-AMINO-4-(TRIFLUOROMETHYL)-2H-CHROMEN-2-ONE;7-AMINO-4-(TRIFLUOROMETHYL)COUMARIN;Coumarin 490;AKOS B000459;COUMARIN 151;Coumarine151;BUTTPARK 20\02-79;Coumarin 490. Coumarin 15;7-AMIDO-4-TRIFLUOROMETHYLCOUMARIN
- CBNumber:
- CB4277334
- Molecular Formula:
- C10H6F3NO2
- Molecular Weight:
- 229.16
- MDL Number:
- MFCD00006858
- MOL File:
- 53518-15-3.mol
- MSDS File:
- SDS
Last updated:2023-05-09 09:30:42
| Melting point | 221-222 °C(lit.) |
|---|---|
| Boiling point | 314.6±42.0 °C(Predicted) |
| Density | 1.4096 (estimate) |
| storage temp. | under inert gas (nitrogen or Argon) at 2–8 °C |
| pka | 1.12±0.20(Predicted) |
| form | Powder |
| color | Yellow |
| Water Solubility | Soluble in dimethyl sulfoxide (25 mg/ml), dimethyl formamide (25 mg/ml), and methanol (25 mg/ml). Insoluble in water. |
| BRN | 4456797 |
| CAS DataBase Reference | 53518-15-3(CAS DataBase Reference) |
| FDA UNII | P5QQ8K4F5Q |
| EPA Substance Registry System | 2H-1-Benzopyran-2-one, 7-amino-4-(trifluoromethyl)- (53518-15-3) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319-H335 | |||||||||
| Precautionary statements | P261-P264-P271-P280-P302+P352-P305+P351+P338 | |||||||||
| Hazard Codes | Xi,Xn | |||||||||
| Risk Statements | 36/37/38-20/21/22 | |||||||||
| Safety Statements | 26-36-37/39 | |||||||||
| WGK Germany | 3 | |||||||||
| TSCA | T | |||||||||
| HazardClass | IRRITANT | |||||||||
| HS Code | 29322090 | |||||||||
| NFPA 704 |
|
Coumarin 151 price More Price(38)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 248924 | 7-Amino-4-(trifluoromethyl)coumarin ≥99% | 53518-15-3 | 250mg | $59.4 | 2024-03-01 | Buy |
| Sigma-Aldrich | 248924 | 7-Amino-4-(trifluoromethyl)coumarin ≥99% | 53518-15-3 | 1g | $196 | 2024-03-01 | Buy |
| Alfa Aesar | A18400 | 7-Amino-4-(trifluoromethyl)coumarin, 99% | 53518-15-3 | 0.25g | $34.65 | 2024-03-01 | Buy |
| Alfa Aesar | A18400 | 7-Amino-4-(trifluoromethyl)coumarin, 99% | 53518-15-3 | 1g | $110 | 2024-03-01 | Buy |
| TRC | A593890 | 7-Amino-4-(trifluoromethyl)coumarin | 53518-15-3 | 250mg | $85 | 2021-12-16 | Buy |
Coumarin 151 Chemical Properties,Uses,Production
Chemical Properties
Coumarin 151 is yellow powder
Uses
Coumarin 151 is used to prepare peptidase substrates and for the synthesis of substrates for the fluorometric assay of proteolytic enzymes in biological fluids.
Uses
7-Amino-4-(trifluoromethyl)coumarin is used in the synthesis of substrates for the fluorometric assay of proteolytic enzymes in biological fluids. It is suitable as laser dye.
Definition
ChEBI: 7-amino-4-(trifluoromethyl)coumarin is a member of 7-aminocoumarins. It has a role as a fluorochrome.
Purification Methods
Purify the coumarin by column chromatography on a C18 column, elute with acetonitrile/0.01M H2O/HCl (1:1), and recrystallise it from isopropanol. Alternatively, it is eluted from a silica gel column with CH2Cl2, or by extracting a CH2Cl2 solution (4g/L) with 1M aqueous NaOH (3 x 0.1L), followed by drying (MgSO4), filtration and evaporation. [Bissell J Org Chem 45 2283 1980, Zimmermann et al. Anal Biochem 70 258 1976.]
Coumarin 151 Preparation Products And Raw materials
Global( 199)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Hangzhou FandaChem Co.,Ltd. | 008657128800458; +8615858145714 | fandachem@gmail.com | China | 9348 | 55 |
| Chengdu GLP biotechnology Co Ltd | 028-87075086 13350802083 | scglp@glp-china.com | CHINA | 1824 | 58 |
| Changzhou Ansciep Chemical Co., Ltd. | +86 519 86305871 | sales@ansciepchem.com | CHINA | 4242 | 58 |
| Accela ChemBio Inc. | (+1)-858-699-3322 | info@accelachem.com | United States | 19965 | 58 |
| Wuhan Chemwish Technology Co., Ltd | 027-67849912 | sales@chemwish.com | CHINA | 10828 | 58 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49390 | 58 |
| Zhengzhou Alfa Chemical Co.,Ltd | +8618530059196 | sale04@alfachem.cn | China | 12468 | 58 |
| Hefei TNJ Chemical Industry Co.,Ltd. | 0551-65418671 | sales@tnjchem.com | China | 34572 | 58 |
| Shanghai UCHEM Inc. | +862156762820 +86-13564624040 | sales@myuchem.com | China | 6710 | 58 |
| Finetech Industry Limited | +86-27-87465837 +8618971612321 | info@finetechnology-ind.com | China | 9702 | 58 |
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JR-8280, 7-Amino-4-(trifluoromethyl)coumarin, 97%
AFC
7-AMINO-4-(TRIFLUOROMETHYL)-2H-CHROMEN-2-ONE
7-AMINO-4-(TRIFLUOROMETHYL)COUMARIN
Coumarine151
53518-15-3
C10H6F3NO2
ALDEHYDE
Luminescent Compounds/Detection
Stains and Dyes
Biochemicals and Reagents
BioChemical
Scintillators
Coumarin