ChemicalBook >> CAS DataBase List >>5-Chlorothiophene-2-sulfonyl chloride
5-Chlorothiophene-2-sulfonyl chloride
- CAS No.
- 2766-74-7
- Chemical Name:
- 5-Chlorothiophene-2-sulfonyl chloride
- Synonyms
- AKOS B019398;BUTTPARK 27\04-09;TIMTEC-BB SBB003378;ART-CHEM-BB B019398;5-chlorothiophene-2-sulfonyl;5-CHLORO-2-THIENYLSULFONYL CHLORIDE;5-CHLOROTHIOPHENESULPHONYL CHLORIDE;5-Chlorothiophen-2-sulfonyl chloride;5-CHLOROTHIOPHENESULFONYLCHLORIDE,96%;2-Chloro-5-(chlorosulphonyl)thiophene
- CBNumber:
- CB4283960
- Molecular Formula:
- C4H2Cl2O2S2
- Molecular Weight:
- 217.09
- MDL Number:
- MFCD00051667
- MOL File:
- 2766-74-7.mol
- MSDS File:
- SDS
Last updated:2023-04-23 13:52:06
| Melting point | 25-28°C |
|---|---|
| Boiling point | 112-117 °C (lit.) |
| Density | 1.623 g/mL at 25 °C (lit.) |
| refractive index |
n |
| Flash point | >230 °F |
| storage temp. | 2-8°C |
| form | solid |
| Specific Gravity | 1.623 |
| color | Colorless to Yellow to Orange |
| Water Solubility | Not miscible in water. |
| Sensitive | Moisture Sensitive |
| BRN | 130710 |
| InChIKey | SORSTNOXGOXWAO-UHFFFAOYSA-N |
| CAS DataBase Reference | 2766-74-7(CAS DataBase Reference) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS05 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Danger | |||||||||
| Hazard statements | H314 | |||||||||
| Precautionary statements | P280-P303+P361+P353-P304+P340+P310-P305+P351+P338-P363-P405 | |||||||||
| Hazard Codes | C | |||||||||
| Risk Statements | 34-29-14 | |||||||||
| Safety Statements | 26-27-36/37/39-45-28A-25 | |||||||||
| RIDADR | UN 3265 8/PG 2 | |||||||||
| WGK Germany | 3 | |||||||||
| Hazard Note | Corrosive | |||||||||
| HazardClass | 8 | |||||||||
| PackingGroup | II | |||||||||
| HS Code | 29349990 | |||||||||
| NFPA 704 |
|
5-Chlorothiophene-2-sulfonyl chloride price More Price(36)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 544272 | 5-Chlorothiophene-2-sulfonyl chloride 96% | 2766-74-7 | 5g | $17.16 | 2024-03-01 | Buy |
| Sigma-Aldrich | 544272 | 5-Chlorothiophene-2-sulfonyl chloride 96% | 2766-74-7 | 1g | $25 | 2023-06-20 | Buy |
| TCI Chemical | C2343 | 5-Chloro-2-thiophenesulfonyl Chloride >98.0%(GC)(T) | 2766-74-7 | 5g | $59 | 2024-03-01 | Buy |
| TCI Chemical | C2343 | 5-Chloro-2-thiophenesulfonyl Chloride >98.0%(GC)(T) | 2766-74-7 | 25g | $236 | 2024-03-01 | Buy |
| Alfa Aesar | A11348 | 5-Chlorothiophene-2-sulfonyl chloride, 97% | 2766-74-7 | 1g | $39.65 | 2024-03-01 | Buy |
5-Chlorothiophene-2-sulfonyl chloride Chemical Properties,Uses,Production
Chemical Properties
5-Chlorothiophene-2-sulfonyl chloride is white to yellow crystalline low melting solid
Uses
5-Chloro-2-thiophenesulfonyl Chloride is a sulfonylthiophene derivative used in the preparation of Notch-1-sparing γ-secretase inhibitors for the treatment of Alzheimer's disease.
Uses
5-Chlorothiophene-2-sulfonyl chloride is an important raw material and intermediate used in Organic Synthesis, Pharmaceuticals, Agrochemicals and Dyestuffs. It is used in the preparation of Notch-1-sparing γ-secretase inhibitors for the treatment of Alzheimer's disease.
Synthesis Reference(s)
Tetrahedron, 21, p. 1333, 1965 DOI: 10.1016/S0040-4020(01)98293-6
General Description
5-Chlorothiophene-2-sulfonyl chloride can be prepared from 2-chlorothiophene by reacting with chlorosulfonic acid in the presence of phosphorus pentachloride.
5-Chlorothiophene-2-sulfonyl chloride Preparation Products And Raw materials
Raw materials
Preparation Products
Global( 261)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Capot Chemical Co.,Ltd. | 571-85586718 +8613336195806 | sales@capotchem.com | China | 29797 | 60 |
| career henan chemical co | +86-0371-86658258 | sales@coreychem.com | China | 29914 | 58 |
| Shenzhen Nexconn Pharmatechs Ltd | +86-755-89396905 +86-15013857715 | admin@nexconn.com | China | 7836 | 58 |
| Chongqing Chemdad Co., Ltd | +86-023-61398051 +8613650506873 | sales@chemdad.com | China | 39916 | 58 |
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63711 | 58 |
| Wuhan Chemwish Technology Co., Ltd | 027-67849912 | sales@chemwish.com | CHINA | 10828 | 58 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 47465 | 58 |
| SIMAGCHEM CORP | +86-13806087780 | sale@simagchem.com | China | 17367 | 58 |
| Hefei TNJ Chemical Industry Co.,Ltd. | 0551-65418671 | sales@tnjchem.com | China | 34572 | 58 |
| WinWin Chemical CO., Limited | +86-0086-577-64498589 +86-15355981851 | sales@win-winchemical.com | China | 13848 | 58 |
View Lastest Price from 5-Chlorothiophene-2-sulfonyl chloride manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2019-07-06 | 5-Chlorothiophene-2-sulfonyl chloride
2766-74-7
|
US $2.00 / KG | 1KG | 99% | Customise | Career Henan Chemical Co |
-
- 5-Chlorothiophene-2-sulfonyl chloride
2766-74-7
- US $2.00 / KG
- 99%
- Career Henan Chemical Co
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ART-CHEM-BB B019398
BUTTPARK 27\04-09
AKOS B019398
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2-Thiophenesulfonyl chloride, 5-chloro-
5-Chloro-2-thiophenesulfonyl Chloride >
2766-74-7
2766-74-4
C4H2Cl2O2S2
C4H2O2Cl2S2
C4H2O2S2Cl2
C4H2Cl2S2O2
Building Blocks
Heterocyclic Building Blocks
Halogenated Heterocycles
Thiophenes
Building Blocks
C4 to C6
Chemical Synthesis
Halogenated Heterocycles
Heterocyclic Building Blocks
Heterocycle-oher series
Halogenated Heterocycles
Heterocyclic Building Blocks
Thiophenes
ThiophenesBuilding Blocks
Thiophene&Benzothiophene
Thiophene intermediates
Heterocycles