Ethyl methanesulfonate
- CAS No.
- 62-50-0
- Chemical Name:
- Ethyl methanesulfonate
- Synonyms
- EMS;ETHYL MESYLATE;METHANESULFONIC ACID ETHYL ESTER;CB 1528;Ethyl methansulfonate;ETHYL METHANESULPHONATE;ethylesterofmethylsulfonicacid;ethylesterofmethanesulfonicacid;ethylesterofmethylsulphonicacid;ethylesterofmethanesulphonicacid
- CBNumber:
- CB4292779
- Molecular Formula:
- C3H8O3S
- Molecular Weight:
- 124.16
- MDL Number:
- MFCD00007559
- MOL File:
- 62-50-0.mol
- MSDS File:
- SDS
| Melting point | <25 °C |
|---|---|
| Boiling point | 85-86 °C/10 mmHg (lit.) |
| Density | 1.206 g/mL at 20 °C |
| vapor pressure | 0.27 hPa (25 °C) |
| refractive index |
n |
| Flash point | 100 °C |
| storage temp. | 2-8°C |
| solubility | 50-100g/l |
| form | liquid |
| color | Colourless to Pale Yellow |
| Water Solubility | Miscible with water. |
| Sensitive | Moisture Sensitive |
| Merck | 14,3827 |
| BRN | 773969 |
| Stability | Stable. Combustible. Incompatible with water, alkalies, oxidizing agents. |
| InChIKey | PLUBXMRUUVWRLT-UHFFFAOYSA-N |
| CAS DataBase Reference | 62-50-0(CAS DataBase Reference) |
| FDA UNII | 9H154DI0UP |
| Proposition 65 List | Ethyl Methanesulfonate |
| IARC | 2B (Vol. 7, Sup 7) 1987 |
| NIST Chemistry Reference | Methanesulfonic acid, ethyl ester(62-50-0) |
| EPA Substance Registry System | Ethyl methanesulfonate (62-50-0) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |   GHS07,GHS08 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Danger | |||||||||
| Hazard statements | H302-H315-H317-H319-H340-H350-H361f | |||||||||
| Precautionary statements | P202-P280-P301+P312-P302+P352-P305+P351+P338-P308+P313 | |||||||||
| Hazard Codes | T | |||||||||
| Risk Statements | 46-22-40-36/37/38-45 | |||||||||
| Safety Statements | 53-23-36/37/39-45-36/37-37/39-26 | |||||||||
| RIDADR | 2810 | |||||||||
| WGK Germany | 3 | |||||||||
| RTECS | PB2100000 | |||||||||
| F | 10-21 | |||||||||
| TSCA | Yes | |||||||||
| HazardClass | 6.1 | |||||||||
| PackingGroup | II | |||||||||
| HS Code | 29041000 | |||||||||
| NFPA 704 |
|
Ethyl methanesulfonate price More Price(26)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | M0880 | Ethyl methanesulfonate liquid | 62-50-0 | 1g | $43.4 | 2024-03-01 | Buy |
| Sigma-Aldrich | 8.20774 | Ethyl methanesulfonate for synthesis | 62-50-0 | 5ml | $47 | 2024-03-01 | Buy |
| Sigma-Aldrich | 8.20774 | Ethyl methanesulfonate for synthesis | 62-50-0 | 25mL | $153 | 2024-03-01 | Buy |
| Sigma-Aldrich | 72945 | Ethyl methanesulfonate certified reference material, TraceCERT | 62-50-0 | 120mg | $131 | 2024-03-01 | Buy |
| TCI Chemical | M0607 | Ethyl Methanesulfonate >99.0%(GC) | 62-50-0 | 25g | $51 | 2024-03-01 | Buy |
Ethyl methanesulfonate Chemical Properties,Uses,Production
Chemical Properties
Ethyl methane sulfonate is a clear liquid.
Chemical Properties
colourless liquid
Uses
Experimentally as mutagen, teratogen and brain carcinogen.
Uses
Ethyl methanesulfonate is used as mutagen for both mammalian and plant cells. It finds application as a model alkylating agent in the study of deoxyribonucleic acid (DNA) repair processes.
Definition
ChEBI: A methanesulfonate ester resulting from the formal condensation of methanesulfonic acid with ethanol.
General Description
Clear colorless liquid. Denser than water.
Air & Water Reactions
Water soluble.
Reactivity Profile
Ethyl methanesulfonate alkylates nucleophiles such as hydroxy, amino and sulfhydryl groups in model and biological materials. Is hydrolyzed by excess aqueous alkali to non-corrosive and non-toxic products. Is hydrolyzed by water to a highly corrosive product .
Fire Hazard
Ethyl methanesulfonate is combustible.
Biochem/physiol Actions
Ethyl methanesulfonate is a DNA ethylating agent, mutagenic to plants and animals and carcinogenic in mammals. It has been used as a model alkylating agent in studies of DNA repair processes. EMS induces base substitutions of guanine-cytosine (G/C) to adenine-thymine (A/T). EMS also generates point mutations and single nucleotide polymorphisms in genomes. EMS is potential chemical mutagen used for inducing mutation in rice, wheat and Arabidopsis thaliana.
Safety Profile
Confirmed carcinogen with experimental carcinogenic, neoplas tigenic, tumorigenic, and teratogenic data. Poison by ingestion and intraperitoneal routes. Experimental reproductive effects. Human mutation data reported. When heated to decomposition it emits toxic fumes of SOx. See also SULFONATES and ESTERS.
Potential Exposure
Used as a research tool for mutagenesis and carcinogenesis studies. Was considered as a possible human male contraceptive. Also considered as a reversible male hemosterilant for insects and mammalian pests.
Carcinogenicity
Ethyl methanesulfonate is reasonably anticipated to be a human carcinogen based on sufficient evidence of carcinogenicity from studies in experimental animals.
Shipping
UN2810 Toxic liquids, organic, n.o.s., Hazard Class: 6.1; Labels: 6.1-Poisonous materials, Technical Name Required. Military driver shall be given full and complete information regarding shipment and conditions in case of emergency. AR 50-6 deals specifically with the shipment of chemical agents. Shipments of agent will be escorted in accordance with AR 740-32.
Incompatibilities
Vapors may form explosive mixture with air. Incompatible with oxidizers (chlorates, nitrates, peroxides, permanganates, perchlorates, chlorine, bromine, fluorine, etc.); contact may cause fires or explosions. Keep away from alkaline materials, strong bases, strong acids, oxoacids, and epoxides. Contact with moisture may cause hydrolysis or other forms of decomposition
Ethyl methanesulfonate Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Hebei baicao biology science and technology co., ltd | +86-19131911055 +8617824879454 | zhang@hbbocao.com | China | 1035 | 58 |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21695 | 55 |
| Changzhou Ansciep Chemical Co., Ltd. | +86 519 86305871 | sales@ansciepchem.com | CHINA | 4242 | 58 |
| Shenzhen Nexconn Pharmatechs Ltd | +86-755-89396905 +86-15013857715 | admin@nexconn.com | China | 10248 | 58 |
| HaBo Hong Kong Co., Limited. | +86-25-18512596065 | info@habotech.com | CHINA | 933 | 58 |
| Hubei Jusheng Technology Co.,Ltd. | 18871490254 | linda@hubeijusheng.com | CHINA | 28180 | 58 |
| Hebei Guanlang Biotechnology Co., Ltd. | +86-19930503282 | alice@crovellbio.com | China | 8822 | 58 |
| Hubei xin bonus chemical co. LTD | 86-13657291602 | linda@hubeijusheng.com | CHINA | 22968 | 58 |
| Shandong chuangyingchemical Co., Ltd. | 18853181302 | sale@chuangyingchem.com | CHINA | 5909 | 58 |
| Shanghai Longyu Biotechnology Co., Ltd. | +8615821988213 | info@longyupharma.com | China | 2531 | 58 |
View Lastest Price from Ethyl methanesulfonate manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2023-03-27 | Ethyl methanesulfonate
62-50-0
|
US $6.00 / KG | 1KG | 0.99 | 60t | XINGTAI XINGJIU NEW MATERIAL TECHNOLOGY CO., LTD | |
 |
2023-03-06 | Ethyl Methanesulfonate
62-50-0
|
US $10.50 / KG | 1KG | 99% | 10 ton | Hebei Guanlang Biotechnology Co,.LTD | |
 |
2023-02-13 | Ethyl Mesilate
62-50-0
|
US $11.00 / kg | 1kg | 99% | 50MT | Hebei baicao biology science and technology co., ltd |
-
- Ethyl methanesulfonate
62-50-0
- US $6.00 / KG
- 0.99
- XINGTAI XINGJIU NEW MATERIAL TECHNOLOGY CO., LTD
-
- Ethyl Methanesulfonate
62-50-0
- US $10.50 / KG
- 99%
- Hebei Guanlang Biotechnology Co,.LTD
-
- Ethyl Mesilate
62-50-0
- US $11.00 / kg
- 99%
- Hebei baicao biology science and technology co., ltd
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