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ODM-201

ODM-201
ODM-201 structure
CAS No.
1297538-32-9
Chemical Name:
ODM-201
Synonyms
0DM021;ODM-201;ODM-021;ODM 021;CS-1565;BAY-1841788;Darolutamid;Darolutamide;Darolutamide D4;ODM-201(BAY-1841788)
CBNumber:
CB43052901
Molecular Formula:
C19H19ClN6O2
Formula Weight:
398.85
MOL File:
1297538-32-9.mol

ODM-201 Properties

Boiling point:
719.5±60.0 °C(Predicted)
Density 
1.41±0.1 g/cm3(Predicted)
pka
11.10±0.10(Predicted)
FDA UNII
X05U0N2RCO
NCI Dictionary of Cancer Terms
darolutamide
NCI Drug Dictionary
darolutamide

ODM-201 price More Price(4)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Cayman Chemical 25643 ODM-201 ≥98% 1297538-32-9 1mg $35 2021-03-22 Buy
Cayman Chemical 25643 ODM-201 ≥98% 1297538-32-9 5mg $140 2021-03-22 Buy
Cayman Chemical 25643 ODM-201 ≥98% 1297538-32-9 10mg $263 2021-03-22 Buy
Cayman Chemical 25643 ODM-201 ≥98% 1297538-32-9 25mg $569 2021-03-22 Buy

ODM-201 Chemical Properties,Uses,Production

Description

ODM-201 is a novel androgen receptor (AR) inhibit designed to inhibit the growth of prostate cancer cells through binding to the AR to inhibit the  testosterone-induced AR nuclear translocation. It is particularly used in patients with progressive metastatic castration-resistant prostate cancer. It is effective in inhibiting the activity of some mutant ARs emerging during antiandrogen therapies, including the F876L mutation version which is resistant to enzalutamide and ARN-509 (the second-generation antiandrogens).Therefore, it has potential to overcome the resistance issue occurring upon AR-targeted therapies.

References

Moilanen, Anu Maarit, et al. "Discovery of ODM-201, a new-generation androgen receptor inhibitor targeting resistance mechanisms to androgen signaling-directed prostate cancer therapies." Sci Rep 5.2(2015):12007. Fizazi, Karim, et al. "ODM-201, a new generation androgen receptor inhibitor for castration-resistant prostate cancer: Preclinical and phase I data." Genitourinary Cancers Symposium of the Conquer-Cancer-Foundation of 2013. Fizazi, K, et al. "Activity and safety of ODM-201 in patients with progressive metastatic castration-resistant prostate cancer (ARADES): an open-label phase 1 dose-escalation and randomised phase 2 dose expansion trial." Lancet Oncology 5.9(2014):975-85.

ODM-201 Preparation Products And Raw materials

Raw materials

Preparation Products


ODM-201 Suppliers

Global( 90)Suppliers
Supplier Tel Fax Email Country ProdList Advantage
Shenzhen Excellent Biotech Co., Ltd.
13480692018
ramyan@ex-biotech.com;sale@ex-biotech.com CHINA 955 58
Henan DaKen Chemical CO.,LTD.
+86-371-66670886
info@dakenchem.com China 21032 58
Henan Tianfu Chemical Co.,Ltd.
0371-55170693
0371-55170693 info@tianfuchem.com CHINA 22607 55
Hangzhou FandaChem Co.,Ltd.
008615858145714
+86-571-56059825 fandachem@gmail.com CHINA 8882 55
ATK CHEMICAL COMPANY LIMITED
+86 21 5161 9050/ 5187 7795
+86 21 5161 9052/ 5187 7796 ivan@atkchemical.com CHINA 26734 60
career henan chemical co
+86-371-86658258
sales@coreychem.com CHINA 29961 58
Jinan Carbotang Biotech Co.,Ltd.
+86 15866703830
figo.gao@foxmail.com CHINA 2778 58
BOC Sciences
1-631-485-4226
1-631-614-7828 inquiry@bocsci.com United States 19753 58
Chongqing Chemdad Co., Ltd
+86-13650506873
sales@chemdad.com CHINA 37282 58
Target Molecule Corp
18019718960 781-999-5354
marketing@targetmol.com United States 19232 58

Related articles

  • Preparation of ODM-201
  • ODM-201 is a new generation AR inhibitor with superior preclinical efficacy compared to enzalutamide and bicalutamide, it does....
  • Nov 12,2019

View Lastest Price from ODM-201 manufacturers

Image Release date Product Price Min. Order Purity Supply Ability Manufacturer
2021-10-08 ODM-201;Darolutamide;BAY-1841788
1297538-32-9
US $285.00-0.00 / g 1ASSAYS 98%+ 10kgs Wuhan Nutra Biotechnology Co.,Ltd
2021-07-02 Darolutamide
1297538-32-9
US $15.00-10.00 / KG 1KG 99%+ HPLC Monthly supply of 1 ton Zhuozhou Wenxi import and Export Co., Ltd
2021-04-16 Darolutamide
1297538-32-9
US $1.00 / KG 1KG 99% 5000KG Shenzhen Excellent Biotech Co., Ltd.

1297538-32-9(ODM-201)Related Search:


  • CS-1565
  • ODM-201(Darolutamide)
  • N-{(2S)-1-[3-(3-chloro-4-cyanophenyl)-1H-pyrazol-1-yl]propan-2-yl}-5-[(1RS)-1-hydroxyethyl]-1H-pyrazole-3-carboxamide
  • 0DM021
  • BAY-1841788;ODM-021;0DM021;ODM 021
  • ODM 021
  • ODM-021
  • ODM-201
  • BAY-1841788
  • N-[(1S)-2-[3-(3-Chloro-4-cyanophenyl)-1H-pyrazol-1-yl]-1-methylethyl]-5-(1-hydroxyethyl)-1H-pyrazole-3-carboxamide
  • Darolutamide
  • N-((S)-1-(3-(3-chloro-4-cyanophenyl)-1H-pyrazol-1-yl)propan-2-yl)-5-(1-hydroxyethyl)-1H-pyrazole-3-carboxamide
  • Darolutamide (ODM-201)
  • ODM-201(BAY-1841788)
  • DAROLUTAMIDE;BAY-1841788
  • 1H-Pyrazole-3-carboxamide, N-[(1S)-2-[3-(3-chloro-4-cyanophenyl)-1H-pyrazol-1-yl]-1-methylethyl]-5-(1-hydroxyethyl)-
  • Darolutamid
  • Darolutamide D4
  • 1297538-32-9
  • C19H19ClN6O2
  • API
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