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3-(4-BROMOPHENYL)-1-METHYLPYRROLIDINE

CAS No.
1088410-99-4
Chemical Name:
3-(4-BROMOPHENYL)-1-METHYLPYRROLIDINE
Synonyms
3-(4-BROMOPHENYL)-1-METHYLPYRROLIDINE;Pyrrolidine, 3-(4-bromophenyl)-1-methyl-
CBNumber:
CB43067161
Molecular Formula:
C11H14BrN
Molecular Weight:
240.14
MDL Number:
MOL File:
1088410-99-4.mol
MSDS File:
SDS
Last updated:2026-05-28 02:51:05
Product description Number Pack Size Price
3-(4-Bromophenyl)-1-methylpyrrolidine 97% AS116503 1g $986
3-(4-Bromophenyl)-1-Methylpyrrolidine 95% AA00968K 100mg $235
3-(4-Bromophenyl)-1-Methylpyrrolidine 95% AA00968K 250mg $474
3-(4-Bromophenyl)-1-Methylpyrrolidine 95% AA00968K 1g $1430
3-(4-bromophenyl)-1-methylpyrrolidine 95% S87356 250MG $425

3-(4-BROMOPHENYL)-1-METHYLPYRROLIDINE Properties

Boiling point 283.8±33.0 °C(Predicted)
Density 1.333±0.06 g/cm3(Predicted)
storage temp. 2-8°C
pka 9.91±0.40(Predicted)

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H302-H317
Precautionary statements  P280

3-(4-BROMOPHENYL)-1-METHYLPYRROLIDINE price More Price(19)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Activate Scientific AS116503 3-(4-Bromophenyl)-1-methylpyrrolidine 97% 1088410-99-4 1g $986 2026-06-04 Buy
aablocks AA00968K 3-(4-Bromophenyl)-1-Methylpyrrolidine 95% 1088410-99-4 100mg $235 2026-05-28 Buy
aablocks AA00968K 3-(4-Bromophenyl)-1-Methylpyrrolidine 95% 1088410-99-4 250mg $474 2026-05-28 Buy
aablocks AA00968K 3-(4-Bromophenyl)-1-Methylpyrrolidine 95% 1088410-99-4 1g $1430 2026-05-28 Buy
ACHEMBLOCK S87356 3-(4-bromophenyl)-1-methylpyrrolidine 95% 1088410-99-4 250MG $425 2026-05-27 Buy
Product number Packaging Price Buy
AS116503 1g $986 Buy
AA00968K 100mg $235 Buy
AA00968K 250mg $474 Buy
AA00968K 1g $1430 Buy
S87356 250MG $425 Buy

3-(4-BROMOPHENYL)-1-METHYLPYRROLIDINE Chemical Properties,Uses,Production

Uses

3-(4-Bromophenyl)-1-Methylpyrrolidine (cas# 1088410-99-4) is a useful reagent for the preparation of pyrazolopyrimidines for treatment and prevention of ALK2-mediated diseases.

Synthesis

Formaldehyde

50-00-0

3-(4-BROMO-PHENYL)-PYRROLIDINE

328546-98-1

3-(4-BROMOPHENYL)-1-METHYLPYRROLIDINE

1088410-99-4

The general procedure for the synthesis of 3-(4-bromophenyl)-1-methylpyrrolidine from formaldehyde and the compound (CAS:328546-98-1) was as follows: referring to the method of Example 11, formalin (0.0452 mL, 0.557 mmol), acetic acid (0.0319 mL, 0.557 mmol) and triacetoxyborohydride (118 mg , 0.557 mmol) were added to a chloroform-ethanol (3:1, 2 mL) solvent mixture containing 3-(4-bromophenyl)pyrrolidine (42 mg, 0.186 mmol). The reaction mixture was stirred at room temperature for 40 min. After completion of the reaction, the reaction solution was diluted with ethyl acetate and the diluted solution was washed with 10% aqueous sodium bicarbonate. The organic layer was dried over anhydrous sodium sulfate, filtered and concentrated under reduced pressure to give 43 mg of the title compound in 97% yield. The product was analyzed by mass spectrometry (GC) at m/z 239 [M]+, 1H-NMR (400 MHz, CDCl3) δ: 1.71-1.88 (1H, m), 2.29-2.50 (5H, m), 2.61-2.69 (1H, m), 2.72-2.80 (1H, m), 2.94-3.00 (1H, m), 3.28 -3.38 (1H, m), 7.15 (2H, d, J = 8.3 Hz), 7.40 (2H, d, J = 8.3 Hz).

References

[1] Patent: EP2166015, 2010, A1. Location in patent: Page/Page column 28

3-(4-BROMOPHENYL)-1-METHYLPYRROLIDINE Preparation Products And Raw materials

3-(4-BROMOPHENYL)-1-METHYLPYRROLIDINE Suppliers

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3-(4-BROMOPHENYL)-1-METHYLPYRROLIDINE Pyrrolidine, 3-(4-bromophenyl)-1-methyl- 1088410-99-4