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Retinyl acetate

Description Reference
Retinyl acetate
Retinyl acetate structure
CAS No.
127-47-9
Chemical Name:
Retinyl acetate
Synonyms
Myvak;Myvax;retinyl;Crystalets;VitaMin A ace;(2E,4E,6E,8E);Davitan A 650;Retinylacetat;tinyl acetate;ARetinyl acet
CBNumber:
CB4308339
Molecular Formula:
C22H32O2
Formula Weight:
328.49
MOL File:
127-47-9.mol

Retinyl acetate Properties

Melting point:
57-58 °C
Boiling point:
406.22°C (rough estimate)
Density 
1.0474 (rough estimate)
refractive index 
1.547-1.555
Flash point:
14℃
storage temp. 
2-8°C
solubility 
absolute ethanol: 25 mg/mL
form 
solid or viscous liquid
color 
Yellow powder
Odor
Amine like
Water Solubility 
soluble
Sensitive 
Light & Air Sensitive & Hygroscopic
Merck 
14,10013
BRN 
1915439
InChIKey
QGNJRVVDBSJHIZ-QHLGVNSISA-N
CAS DataBase Reference
127-47-9(CAS DataBase Reference)
FDA 21 CFR
582.5933; 310.545
Substances Added to Food (formerly EAFUS)
VITAMIN A ACETATE
SCOGS (Select Committee on GRAS Substances)
Vitamin A acetate
FDA UNII
3LE3D9D6OY
NIST Chemistry Reference
Retinol, acetate(127-47-9)
NCI Drug Dictionary
retinyl acetate
EPA Substance Registry System
Retinol acetate (127-47-9)
SAFETY
  • Risk and Safety Statements
Symbol(GHS) 
GHS02,GHS07,GHS08
Signal word  Danger
Hazard statements  H315-H361-H225-H319-H360-H413
Precautionary statements  P210-P280-P305+P351+P338-P337+P313-P403+P235-P201-P308+P313-P321-P405-P501a
Hazard Codes  Xn,Xi,T,F
Risk Statements  38-63-36/37/38-53-61-11
Safety Statements  36/37-45-37/39-26-53-16
RIDADR  UN1170 - class 3 - PG 2 - Ethanol
WGK Germany  2
RTECS  VH6825000
1-8-10
TSCA  Yes
HS Code  29362100
Toxicity LD50 (10 day) orally in mice: 4100 mg/kg (Kamm)

Retinyl acetate price More Price(25)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich V-040 Retinyl acetate solution 100?μg/mL in ethanol (with 0.1% (w/v) BHT; degassed), reference material, Cerilliant? 127-47-9 1 mL $83 2021-03-22 Buy
Sigma-Aldrich 46958 Retinyl acetate analytical standard 127-47-9 100 mg $111 2021-03-22 Buy
Sigma-Aldrich R0300000 Retinol acetate European Pharmacopoeia (EP) Reference Standard 127-47-9 $190 2021-03-22 Buy
Sigma-Aldrich 95140 Retinyl acetate concentrate (~50% (w/w) in peanut oil), ~1500 U/mg 127-47-9 25g $220 2020-08-18 Buy
Sigma-Aldrich 1716002 Retinyl acetate United States Pharmacopeia (USP) Reference Standard 127-47-9 10x0.5g $371 2021-03-22 Buy

Retinyl acetate Chemical Properties,Uses,Production

Description

Retinyl acetate (retinol acetate, vitamin A acetate) is a natural form of vitamin A. It is the acetate ester of retinol. It consists of yellow crystals which are greasy or sticky. It has a mild, characteristic odor. It has potential antineoplastic and chemo-preventive activities. It can be used to fortify food with vitamin A. As vitamin A acetate can induce cell differentiation and inhibit cell proliferation, it is used in skin-conditioning agent.

Reference

Volker Bühler, Vademecum for Vitamin Formulations, 2001, ISBN 3-8047-1834-5

Chemical Properties

Crystalline

Uses

vitamin precursor

Uses

Essential micronutrient

Safety Profile

Moderately toxic by ingestion. Experimental teratogenic and reproductive effects. Questionable carcinogen with experimental neoplastigenic data. Mutation data reported. When heated to decomposition it emits acrid smoke and irritating fumes. See also VITAMIN A.

Purification Methods

The acetate is separated from retinol by column chromatography, then crystallised from MeOH. [Kofler and Rubin Vitamins and Hormones (NY) 18 315 1960 for purification methods]. Store it in the dark, under N2 or Ar, at 0o. [Beilstein 6 IV 4135.]

Retinyl acetate Preparation Products And Raw materials

Raw materials

Preparation Products


Retinyl acetate Suppliers

Global( 389)Suppliers
Supplier Tel Fax Email Country ProdList Advantage
NANJING SUNSHINE BIOTECH CO.,LTD
+86-25-86189929
+86-25-86189616 brian@sunshine-bio.com CHINA 128 58
Henan DaKen Chemical CO.,LTD.
+86-371-66670886
info@dakenchem.com China 21032 58
Henan Tianfu Chemical Co.,Ltd.
0371-55170693
0371-55170693 info@tianfuchem.com CHINA 22607 55
Hangzhou FandaChem Co.,Ltd.
008615858145714
+86-571-56059825 fandachem@gmail.com CHINA 8882 55
Nanjing ChemLin Chemical Industry Co., Ltd.
025-83697070
product@chemlin.com.cn CHINA 3013 60
Hubei XinRunde Chemical Co., Ltd.
+8615102730682
02783214688 bruce@xrdchem.cn CHINA 567 55
Nanjing Finetech Chemical Co., Ltd.
025-85710122 17714198479
025-85710122 sales@fine-chemtech.com CHINA 890 55
Shanghai Zheyan Biotech Co., Ltd.
18017610038
zheyansh@163.com CHINA 3623 58
career henan chemical co
+86-371-86658258
sales@coreychem.com CHINA 29961 58
SHANDONG ZHI SHANG CHEMICAL CO.LTD
+86 18953170293
+86 0531-67809011 sales@sdzschem.com CHINA 2858 58

View Lastest Price from Retinyl acetate manufacturers

Image Release date Product Price Min. Order Purity Supply Ability Manufacturer
2021-10-14 Retinol acetate;vitamin A palmitate
127-47-9
US $30.00 / Kg/Bag 5KG 1000000-1700000 IU/g 500tons/month Hebei Dongdu Import and Export Co. LTD
2021-09-29 Retinyl acetate
127-47-9
US $0.00 / KG 1KG 98% 500kg/month WUHAN FORTUNA CHEMICAL CO., LTD
2021-08-26 Retinyl Acetate
127-47-9
US $10.70 / g/Bag 10g 76% 10000kg Hebei Crovell Biotech Co Ltd

Retinyl acetate Spectrum


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