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(Z)-Guggulsterone

(Z)-Guggulsterone
(Z)-Guggulsterone
CAS No.
39025-23-5
Chemical Name:
(Z)-Guggulsterone
Synonyms
GUGULSTERONE;GUGGULSTERONE;Z-Gugglesterone;GUGGULSTERONE Z;GUGGULESTERONE Z;(Z)-Guggulsterone;CIS GUGGULSTERONE;GUGGULSTERONE Z(P);GUGGULSTERONE (Z FORM);Guggulsterone Z (25 mg)
CBNumber:
CB4309068
Molecular Formula:
C21H28O2
Formula Weight:
312.45
MOL File:
39025-23-5.mol

(Z)-Guggulsterone Properties

Melting point:
188-190°
alpha 
D26 -61° (c = 1 in chloroform)
storage temp. 
2-8°C
solubility 
DMSO: 5 mg/mL
form 
powder
color 
light yellow
SAFETY
  • Risk and Safety Statements
  • Hazard and Precautionary Statements (GHS)
Hazard Codes  Xi
Risk Statements  37-38
Safety Statements  36
WGK Germany  3
Symbol(GHS):
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning P264, P280, P302+P352, P321,P332+P313, P362
Precautionary statements:

(Z)-Guggulsterone price More Price(4)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 78251 (Z)-Guggulsterone analytical standard 39025-23-5 10mg $227 2018-11-20 Buy
Sigma-Aldrich 1302214 Guggulsterone Z United States Pharmacopeia (USP) Reference Standard 39025-23-5 25mg $852.6 2018-11-20 Buy
Sigma-Aldrich G5168 (Z)-Guggulsterone ≥89% (HPLC), powder 39025-23-5 5mg $161 2018-11-13 Buy
Sigma-Aldrich G5168 (Z)-Guggulsterone ≥89% (HPLC), powder 39025-23-5 25mg $642 2018-11-13 Buy

(Z)-Guggulsterone Chemical Properties,Uses,Production

Uses

Z-Guggulsterone acts as an α-glucosidase inhibitor also known as a hypolipidemic agent.

Biological Activity

Broad spectrum steroid receptor ligand; mineralocorticoid, progesterone and glucocorticoid receptor antagonist (K i values are 37, 224 and 252 nM respectively) and weak androgen receptor agonist (K i = 315 nM). Induces apoptosis in prostate cancer cells and inhibits angiogenesis via suppression of the VEGF-VEGFR2-Akt signalling pathway. Exhibits antilipidemic activity via antagonism of the farnesoid X receptor (FXR) and displays antiseptic, antirheumatic and anti-inflammatory activity in vivo . More active isomer of Guggulsterone (Pregna-4,17(20)-diene-3,16-dione ).

(Z)-Guggulsterone Preparation Products And Raw materials

Raw materials

Preparation Products


(Z)-Guggulsterone Suppliers

Global( 53)Suppliers
Supplier Tel Fax Email Country ProdList Advantage
Biochempartner
0086-13720134139
candy@biochempartner.com CHINA 955 58
career henan chemical co
+86-371-86658258
sales@coreychem.com CHINA 19990 58
Shanghai Zheyan Biotech Co., Ltd.
18017610038
zheyansh@163.com CHINA 3624 58
J & K SCIENTIFIC LTD. 400-666-7788 +86-10-82848833
+86-10-82849933 jkinfo@jkchemical.com;market6@jkchemical.com China 96815 76
3B Pharmachem (Wuhan) International Co.,Ltd. 86-21-50328103 * 801、802、803、804 Mobile:18930552037
86-21-50328109 3bsc@sina.com China 15926 69
Chembest Research Laboratories Limited +86(0)21-20908456
+86(0)21-58180499 sales@biochembest.com; market@biochembest.com China 6054 61
Sinopharm Chemical Reagent Co,Ltd. 86-21-63210123
86-21-63290778 86-21-63218885 sj_scrc@sinopharm.com China 9966 79
UHN Shanghai Research & Development Co., Ltd. +86 (21) 5895-8002
+86 (21) 5895-8628 sales@uhnshanghai.com China 1038 58
Shanghai Aladdin Bio-Chem Technology Co.,LTD 021-20337333/400-620-6333
021-50323701 sale@aladdin-e.com China 25106 65
Shanghai Tauto Biotech Co., Ltd 0086-21-51320588
0086-21-51320502 export2@tautobiotech.com China 3579 66

View Lastest Price from (Z)-Guggulsterone manufacturers

Image Release date Product Price Min. Order Purity Supply Ability Manufacturer
2018-12-25 (E)-Guggulsterone
39025-23-5
US $1.00 / KG 1g 99% 100KG career henan chemical co

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