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mPEG3-CH2COOH

CAS No.
16024-60-5
Chemical Name:
mPEG3-CH2COOH
Synonyms
mPEG3-CH2COOH;m-PEG4-CH2COOH;mPEG3-acetic acid;MeO-(CH2CH2O)3-CH2COOH;3,6,9,12-Tetraoxatridecanoic acid;2,5,8,11-tetraoxatridecan-13-oic acid;2,5,8,11-Tetraoxa-13-tridecanoic Acid;mPEG3-CH2COOH/3,6,9,12-Tetraoxatridecanoic acid;2-[2-[2-(2-methoxyethoxy)ethoxy]ethoxy]acetic acid
CBNumber:
CB43095676
Molecular Formula:
C9H18O6
Molecular Weight:
222.24
MDL Number:
MFCD25959645
MOL File:
16024-60-5.mol
MSDS File:
SDS
Last updated:2024-03-14 17:10:07

mPEG3-CH2COOH Properties

Boiling point 338.4±27.0 °C(Predicted)
Density 1.127±0.06 g/cm3(Predicted)
pka 3.39±0.10(Predicted)

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P261-P305+P351+P338

mPEG3-CH2COOH price More Price(8)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
BroadPharm BP-23432 m-PEG4-CH2COOH 98% 16024-60-5 1g $270 2021-12-16 Buy
Activate Scientific AS104070 mPEG3-CH2COOH 95+% 16024-60-5 1g $292 2021-12-16 Buy
AK Scientific 3727CR 2,5,8,11-Tetraoxatridecan-13-oicacid 16024-60-5 5g $836 2021-12-16 Buy
Activate Scientific AS104070 mPEG3-CH2COOH 95+% 16024-60-5 5G $874 2021-12-16 Buy
Acrotein B-0957 mPEG3-CH2COOH 97% 16024-60-5 0.5g $146.66 2021-12-16 Buy
Product number Packaging Price Buy
BP-23432 1g $270 Buy
AS104070 1g $292 Buy
3727CR 5g $836 Buy
AS104070 5G $874 Buy
B-0957 0.5g $146.66 Buy

mPEG3-CH2COOH Chemical Properties,Uses,Production

Appearance

White or Off-White Solid

Description

m-PEG4-CH2COOH is a PEG linker containing a terminal carboxylic acid. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond. The hydrophilic PEG spacer increases solubility in aqueous media.

Uses

3,6,9,12-Tetraoxatridecanoic acid is a useful research chemical.

Application

mPEG3-CH2COOH can be used to synthesise lipid couplers of oligo-(14-amino-3,6,9,12-tetraoxotetracosanoic acid) (ATTAn) as monodisperse analogues of poly(ethylene glycol) (PEG) derivatives for use in liposomal drug delivery systems[1]. mPEG3-CH2COOH contains terminal carboxylic acids. The terminal carboxylic acid readily reacts with primary and secondary amines under EDC, DCC, HATU or other amide coupling conditions to form stable amide bonds. mPEG modification increases the water solubility of the resulting compounds.

References

[1] STEVEN M. ANSELL. Application of Oligo-(14-amino-3,6,9,12-tetraoxatetradecanoic acid) Lipid Conjugates as Steric Barrier Molecules in Liposomal Formulations[J]. Bioconjugate Chemistry Bioconjugate, 1999. DOI:10.1021/bc990005p.

66664-66-2
16024-60-5
Synthesis of mPEG3-CH2COOH from 3,6,9,12-Tetraoxatridecanoic acid, ethyl ester

mPEG3-CH2COOH Preparation Products And Raw materials

mPEG3-CH2COOH Suppliers

Global( 54)Suppliers
Supplier Tel Email Country ProdList Advantage
XIAMEN SINOPEG BIOTECH CO., LTD.
+86-0592-7761068 +8617350879715 changaiwei@sinopeg.com China 59 58
Hebei Yanxi Chemical Co., Ltd.
+8617531190177 peter@yan-xi.com China 5993 58
Shanghai Daken Advanced Materials Co.,Ltd
+86-371-66670886 info@dakenam.com China 15371 58
9i LLC
+18039569191 MWan@NiNeiLab.com United States 418 58
career henan chemical co
+86-0371-86658258 15093356674; factory@coreychem.com China 29826 58
SHANGHAI T&W PHARMACEUTICAL CO., LTD.
+86-021-61551413 +8618813727289 contact@trustwe.com China 5738 58
TargetMol Chemicals Inc.
+1-781-999-5354 +1-00000000000 marketing@targetmol.com United States 19892 58
Hebei Guanlang Biotechnology Co., Ltd.
+86-19930503259 +86-19930503259 cherry@crovellbio.com China 18458 58
LEAPCHEM CO., LTD.
+86-852-30606658 market18@leapchem.com China 43348 58
Jilin Chinese Academy of Sciences-yanshen Technology
+undefined18143011203 info@chemextension.com China 42057 58

View Lastest Price from mPEG3-CH2COOH manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
3,6,9,12-Tetraoxatridecanoic acid pictures 2023-09-12 3,6,9,12-Tetraoxatridecanoic acid
16024-60-5
US $30.00-2.00 / kg 1kg 0.99 30 tons Hebei Yanxi Chemical Co., Ltd.
3,6,9,12-Tetraoxatridecanoic acid pictures 2023-09-06 3,6,9,12-Tetraoxatridecanoic acid
16024-60-5
US $0.00-0.00 / KG 1KG 99% 500000kg Hebei Guanlang Biotechnology Co., Ltd.
Methoxypoly(ethylene glycol) carboxymethyl pictures 2021-06-02 Methoxypoly(ethylene glycol) carboxymethyl
16024-60-5
US $0.00-0.00 / KG 1G 98% 100kg XIAMEN SINOPEG BIOTECH CO., LTD.
3,6,9,12-Tetraoxatridecanoic acid 2-[2-[2-(2-methoxyethoxy)ethoxy]ethoxy]acetic acid m-PEG4-CH2COOH 2,5,8,11-tetraoxatridecan-13-oic acid mPEG3-acetic acid mPEG3-CH2COOH 2,5,8,11-Tetraoxa-13-tridecanoic Acid MeO-(CH2CH2O)3-CH2COOH mPEG3-CH2COOH/3,6,9,12-Tetraoxatridecanoic acid 16024-60-5