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3PO

CAS No.
13309-08-5
Chemical Name:
3PO
Synonyms
(E)3PO,(E) 3PO;3-(3-Pyridinyl)-1-(4-pyridinyl)-2-propen-1-one;2-Propen-1-one, 3-(3-pyridinyl)-1-(4-pyridinyl)-
CBNumber:
CB43119750
Molecular Formula:
C13H10N2O
Molecular Weight:
210.23
MDL Number:
MOL File:
13309-08-5.mol
Last updated:2023-06-30 15:45:59

3PO Properties

Melting point 144-147°C
Boiling point 387.8±42.0 °C(Predicted)
Density 1.192±0.06 g/cm3(Predicted)
storage temp. Inert atmosphere,Room Temperature
solubility DMSO (Slightly), Methanol (Slightly)
pka 4.20±0.12(Predicted)
form Solid
color Pale Yellow to Yellow

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P261-P305+P351+P338

3PO price More Price(21)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TRC P993045 3-(3-Pyridinyl)-1-(4-pyridinyl)-2-propen-1-one 13309-08-5 50mg $250 2021-12-16 Buy
AK Scientific 3080CP 3-(3-Pyridinyl)-1-(4-pyridinyl)-2-propen-1-one 13309-08-5 50mg $347 2021-12-16 Buy
AK Scientific 3080CP 3-(3-Pyridinyl)-1-(4-pyridinyl)-2-propen-1-one 13309-08-5 10mg $163 2021-12-16 Buy
ApexBio Technology B4939 3PO 13309-08-5 5mg $90 2021-12-16 Buy
ApexBio Technology B4939 3PO 13309-08-5 10mg $135 2021-12-16 Buy
Product number Packaging Price Buy
P993045 50mg $250 Buy
3080CP 50mg $347 Buy
3080CP 10mg $163 Buy
B4939 5mg $90 Buy
B4939 10mg $135 Buy

3PO Chemical Properties,Uses,Production

Uses

3-(3-Pyridinyl)-1-(4-pyridinyl)-2-propen-1-one inhibits human bladder cancer cell lines growth. It also inhibits cancer cell growth proliferation by it’s treatment in combination with phenoformin. An inhibitor of 6-phosphofructo-2- kinaselfructose-2,6-bisphosphatase 3 (PFKFB).

Definition

ChEBI: 3PO is a member of the class of pyridines that is pyridine substituted by a 3-oxo-3-(pyridin-4-yl)prop-1-en-1-yl group at position 3. An inhibitor of PFKFB3 kinase, an enzyme with a key role in glycolysis. It has a role as an antineoplastic agent, an angiogenesis inhibitor, an autophagy inducer, an apoptosis inducer and an EC 2.7.1.105 (6-phosphofructo-2-kinase) inhibitor. It is a member of pyridines and an enone.

storage

Store at -20°C

3PO Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 33)Suppliers
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ATK CHEMICAL COMPANY LIMITED
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UHN Shanghai Research & Development Co., Ltd. 021-58958002 18930822973 SALES@UHNSHANGHAI.COM China 977 58
Nanjing Chalf-Pharm Technology Co., Ltd. 025-57018978 18251899859 sales@chalf-pharm.com China 5951 50
3-(3-Pyridinyl)-1-(4-pyridinyl)-2-propen-1-one 2-Propen-1-one, 3-(3-pyridinyl)-1-(4-pyridinyl)- (E)3PO,(E) 3PO 13309-08-5