ChemicalBook >> CAS DataBase List >>Ethyl 2-chloronicotinate

Ethyl 2-chloronicotinate

CAS No.
1452-94-4
Chemical Name:
Ethyl 2-chloronicotinate
Synonyms
AVAC-001;oronicotinate;Ethyl 2-chloronicoti;Flunixin EP Impurity C;ETHYL 2-CHLORONICOTINATE;ethy-2-chloroisonicoitate;Ethyl2-Chloronicotinate>Flunixin Related CoMpound C;Ethyl2-chloronicotinate,98%;Flunixin Meglumine Impurity C
CBNumber:
CB4312224
Molecular Formula:
C8H8ClNO2
Molecular Weight:
185.61
MDL Number:
MFCD00674129
MOL File:
1452-94-4.mol
Last updated:2023-11-07 16:09:33

Ethyl 2-chloronicotinate Properties

Melting point 68 C
Boiling point 78°C (0.1 mmHg)
Density 1.2445 g/cm3(Temp: 25 °C)
refractive index 1.5210-1.5250
storage temp. Keep in dark place,Sealed in dry,Room Temperature
pka -1.32±0.10(Predicted)
color Colorless to Light yellow to Light orange
InChI InChI=1S/C8H8ClNO2/c1-2-12-8(11)6-4-3-5-10-7(6)9/h3-5H,2H2,1H3
InChIKey PMIMPBYTPPRBGD-UHFFFAOYSA-N
SMILES C1(Cl)=NC=CC=C1C(OCC)=O
CAS DataBase Reference 1452-94-4(CAS DataBase Reference)
FDA UNII 7C4MMV3FW4

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H319
Precautionary statements  P305+P351+P338
Hazard Codes  Xi
Risk Statements  36/37/38
Safety Statements  26-37/39-60-37
HazardClass  IRRITANT
HS Code  29333990
NFPA 704
1
2 0

Ethyl 2-chloronicotinate price More Price(28)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich Y0000445 Flunixin impurity C European Pharmacopoeia (EP) Reference Standard 1452-94-4 y0000445 $153 2024-03-01 Buy
Sigma-Aldrich PHR2413 Flunixin Related Compound C Pharmaceutical Secondary Standard; Certified Reference Material 1452-94-4 50MG $534 2024-03-01 Buy
Sigma-Aldrich 1274631 Flunixin impurity C 1452-94-4 50mg $1720 2024-03-01 Buy
TCI Chemical E0844 Ethyl 2-Chloronicotinate >98.0%(GC) 1452-94-4 25g $44 2024-03-01 Buy
TCI Chemical E0844 Ethyl 2-Chloronicotinate >98.0%(GC) 1452-94-4 100g $130 2024-03-01 Buy
Product number Packaging Price Buy
Y0000445 y0000445 $153 Buy
PHR2413 50MG $534 Buy
1274631 50mg $1720 Buy
E0844 25g $44 Buy
E0844 100g $130 Buy

Ethyl 2-chloronicotinate Chemical Properties,Uses,Production

Chemical Properties

Light yellow liquid

Uses

Ethyl 2-chloronicotinate,is used as a pharmaceutical intermediate.

Synthesis Reference(s)

Tetrahedron, 51, p. 13177, 1995 DOI: 10.1016/0040-4020(95)00788-A

Synthesis

2-Chloropyridine-3-carboxylic acid (7.9 g) and thionyl chloride (45 ml) were heated for 3 hours in benzene (65 ml) under reflux. The reaction mixture was concentrated to leave an oil, which was added dropwise to ethanol (40 ml). The mixture was heated for a further one hour under reflux. The solvent was distilled, and the residue was dissolved in toluene. The solution was dried over anhydrous magnesium sulfate. The solvent was distilled to leave Ethyl 2-chloronicotinate (8.4 g, 90%) as a pale yellow oil.Ethyl 2-chloronicotinate

Ethyl 2-chloronicotinate Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 307)Suppliers
Supplier Tel Email Country ProdList Advantage
Zhengzhou Lingzhiyue Technology Co., Ltd
+86-0371-55074660 +86-13783527580 Lingzhiyue@aliyun.com China 3091 58
Hebei Mojin Biotechnology Co., Ltd
+8613288715578 sales@hbmojin.com China 12453 58
Henan Bao Enluo International TradeCo.,LTD
+86-17331933971 +86-17331933971 deasea125996@gmail.com China 2503 58
Frapp's ChemicalNFTZ Co., Ltd.
+86 (576) 8169-6106 sales@frappschem.com China 885 50
Shanghai Daken Advanced Materials Co.,Ltd
+86-371-66670886 info@dakenam.com China 15371 58
Henan Tianfu Chemical Co.,Ltd.
+86-0371-55170693 +86-19937530512 info@tianfuchem.com China 21695 55
career henan chemical co
+86-0371-86658258 sales@coreychem.com China 29914 58
Accela ChemBio Inc.
(+1)-858-699-3322 info@accelachem.com United States 19965 58
Hebei Guanlang Biotechnology Co., Ltd.
+86-19930503282 alice@crovellbio.com China 8822 58
Standardpharm Co. Ltd.
86-714-3992388 overseasales1@yongstandards.com United States 14336 58

View Lastest Price from Ethyl 2-chloronicotinate manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
 Ethyl 2-chloronicotinate pictures 2024-03-28 Ethyl 2-chloronicotinate
1452-94-4
US $0.00 / KG 25KG 99.7% Inquiry PNP Biotech Co. Ltd
Ethyl 2-chloronicotinate pictures 2023-08-02 Ethyl 2-chloronicotinate
1452-94-4
US $50.00 / kg 1kg 99.9% 10000MT Henan Bao Enluo International TradeCo.,LTD
Ethyl 2-chloronicotinate pictures 2023-07-01 Ethyl 2-chloronicotinate
1452-94-4
US $0.00 / KG 1KG 99% 50000KG/month Hebei Mojin Biotechnology Co., Ltd
ETHYL 2-CHLORONICOTINATE ethyl 2-chloropyridine-3-carboxylate 2-CHLORONICOTINIC ACID ETHYL ESTER 2-Chloro-3-pyridinecarboxylic acid ethyl ester 2-Chloropyridine-3-carboxylic acid ethyl ester Ethyl 2-chloronicoti Ethyl 2-Chloro-3-pyridinecarboxylate 2-Chloronicotinic Acid Ethyl Ester Ethyl 2-Chloro-3-pyridinecarboxylate 2-Chloro-3-pyridinecarboxylic Acid Ethyl Ester 2-Chloronicotinate ethyl ester Ethyl 2-chloropyridine-3-carboxylate, 2-Chloro-3-(ethoxycarbonyl)pyridine Flunixin Related CoMpound C Ethyl 2-chloronicotinate, 99%, 99% Ethyl2-chloronicotinate,98% AVAC-001 oronicotinate Flunixin Meglumine Impurity 3(Flunixin Meglumine EP Impurity C) Flunixin Meglumine EP Impurity C Ethyl2-Chloronicotinate> Ethyl 2-Chloropyridine-3-carboxylat Flunixin EP Impurity C Flunixin impurity CQ: What is Flunixin impurity C Q: What is the CAS Number of Flunixin impurity C Q: What is the storage condition of Flunixin impurity C Q: What are the applications of Flunixin impurity C Flunixin Related Compound C (Ethyl 2-chloronicotinate) (1274631) Flunixin USP Related Compound C ethy-2-chloroisonicoitate Flunixin Meglumine Impurity C 1452-94-4 C8HBCINO2 pyridine series Pyridines Pharmaceutical Intermediates Pyridine Fluorobenzene