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Luotonin F

CAS No.
244616-85-1
Chemical Name:
Luotonin F
Synonyms
Luotonin F;Luotonin F Exclusive;2-(quinoline-3-carbonyl)-1H-quinazolin-4-one;2-(3-quinolinylcarbonyl)-4(3H)-quinazolinone;4(3H)-Quinazolinone, 2-(3-quinolinylcarbonyl)-
CBNumber:
CB43152667
Molecular Formula:
C18H11N3O2
Molecular Weight:
301.3
MDL Number:
MOL File:
244616-85-1.mol
Last updated:2023-05-21 10:59:17

Luotonin F Properties

Boiling point 542.0±42.0 °C(Predicted)
Density 1.38±0.1 g/cm3(Predicted)
storage temp. Store at -20°C
solubility ≤2.5mg/ml in DMSO;2.5mg/ml in dimethyl formamide
form crystalline solid
pka 2.06±0.11(Predicted)

Luotonin F price More Price(5)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Cayman Chemical 14254 Luotonin F ≥98% 244616-85-1 1mg $44 2024-03-01 Buy
Cayman Chemical 14254 Luotonin F ≥98% 244616-85-1 5mg $172 2024-03-01 Buy
Cayman Chemical 14254 Luotonin F ≥98% 244616-85-1 10mg $299 2024-03-01 Buy
Cayman Chemical 14254 Luotonin F ≥98% 244616-85-1 25mg $692 2024-03-01 Buy
ApexBio Technology C4228 LuotoninF 244616-85-1 10mg $339 2021-12-16 Buy
Product number Packaging Price Buy
14254 1mg $44 Buy
14254 5mg $172 Buy
14254 10mg $299 Buy
14254 25mg $692 Buy
C4228 10mg $339 Buy

Luotonin F Chemical Properties,Uses,Production

Biological Activity

luotonin f is an alkaloid found in the aerial parts of the peganum nigellastrum bunge, a plant which has been long used in traditional chinese medicine for the treatment of rheumatism, abscesses, and various other inflammatory conditions [1].due to their biological and pharmaceutical activities, many synthetic methods have been developed for the synthesis of luotonins. an efficient one-pot synthetic protocol has been proposed for the synthesis of luntonin f from easily available starting materials. through the rational logical design, multifundamental reactions were assembled in one-pot, such as iodination, kornblum oxidation, and annulations [2]. the developed approach could efficiently synthesize luntonin f and various analogues. luotonin f showed promising cytotoxicity against leukemia p-388 cells with an ic50 value of 2.3 μg/ml by stabilizing the dna topoisomerase i-dna complex [1].

References

[1] liang j l, cha h c, jahng y. recent advances in the studies on luotonins[j]. molecules, 2011, 16(6): 4861-4883.
[2] zhu y, fei z, liu m, et al. direct one-pot synthesis of luotonin f and analogues via rational logical design[j]. organic letters, 2012, 15(2): 378-381.

Luotonin F Preparation Products And Raw materials

Raw materials

Preparation Products

Luotonin F Suppliers

Global( 18)Suppliers
Supplier Tel Email Country ProdList Advantage
ChemeGen(Shanghai) Biotechnology Co.,Ltd. 18818260767 sales@chemegen.com China 11289 58
MedBioPharmaceutical Technology Inc 021-69568360 18916172912 order@med-bio.cn China 8141 58
Shanghai Yifei Biotechnology Co. , Ltd. 021-65675885 18964387627 customer_service@efebio.com China 8740 58
ApexBio Technology -- sales@apexbt.com United States 6254 58
Luotonin F 2-(quinoline-3-carbonyl)-1H-quinazolin-4-one Luotonin F Exclusive 4(3H)-Quinazolinone, 2-(3-quinolinylcarbonyl)- 2-(3-quinolinylcarbonyl)-4(3H)-quinazolinone 244616-85-1