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Roxarsone

CAS No.
121-19-7
Chemical Name:
Roxarsone
Synonyms
ristat;3-nitro;Roxasone;ROXARSON;nsc-2101;reno-sal;ROXARSONE;aklomix-3;ren-o-sal;3-nitro-10
CBNumber:
CB4318736
Molecular Formula:
C6H6AsNO6
Molecular Weight:
263.04
MDL Number:
MFCD00007112
MOL File:
121-19-7.mol
Last updated:2023-05-15 10:43:34

Roxarsone Properties

Melting point ≥300 °C(lit.)
Boiling point 537.3±60.0 °C(Predicted)
Density 2.02 g/cm3
storage temp. 0-6°C
solubility insoluble in Ether
pka 3.51±0.10(Predicted)
form liquid
color Light yellow to Yellow
Water Solubility <0.1 g/100 mL at 23 ºC
Merck 14,8273
BRN 1976533
Stability Hygroscopic
InChIKey XMVJITFPVVRMHC-UHFFFAOYSA-N
CAS DataBase Reference 121-19-7(CAS DataBase Reference)
FDA UNII H5GU9YQL7L
EPA Substance Registry System Roxarsone (121-19-7)

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictogramsGHS hazard pictograms
GHS06,GHS09
Signal word  Danger
Hazard statements  H301+H331-H410
Precautionary statements  P261-P264-P270-P273-P301+P310-P304+P340+P311
Hazard Codes  T,N
Risk Statements  23/25-50/53
Safety Statements  20/21-28-45-60-61
RIDADR  UN 3465 6.1/PG 2
WGK Germany  3
RTECS  CY5250000
HazardClass  6.1(b)
PackingGroup  III
HS Code  29319090
Toxicity LD50 in rats, chickens (mg/kg): 155, 110-123 orally; 66, 34 i.p. (Kerr)
NFPA 704
1
2 0

Roxarsone Chemical Properties,Uses,Production

Chemical Properties

BEIGE-BROWN FINE CRYSTALLINE POWDER

Uses

antiinfective, preservative

Uses

Formerly in manufacture of arsphenamines; as reagent for zirconium.

Uses

4-Hydroxy-3-nitrophenylarsonic Acid is used as a feed additive for chicken to aid in the prevention of coccidiosis caused by E[imeria] tenella and E. necatrix.

Definition

ChEBI: An organoarsonic acid where the organyl group is 4-hydroxy-3-nitrophenyl.

General Description

Pale yellow crystals or light tan powder.

Air & Water Reactions

Insoluble in water.

Reactivity Profile

May be sensitive to light and elevated temperatures on long-term storage. Roxarsone puffs up and deflagrates on heating. Incompatible with strong oxidizers and strong acids. Forms mono-, di-, and trisodium salts.

Hazard

Toxic by ingestion, highly toxic.

Fire Hazard

Flash point data are not available for Roxarsone ; however, Roxarsone is probably combustible.

Purification Methods

It crystallises from water and is used for the spectroscopic detection of Zn. [Beilstein 16 II 468, 16 III 1073, 16 IV 1188.]

2-NITROPHENOL-4-ARSONIC ACID 4-HYDROXY-3-NITROBENZENENEARSONIC ACID 4-HYDROXY-3-NITROBENZENEARSONIC ACID 4-HYDROXY-3-NITROPHENYLARSONIC ACID 4-Hydroxy-3-nitrobenzenearsonic acid,98% Roxarsone (200 mg) Roxasone p-Hydroxy-M-nitrophenylarsonic Acid 4-Hydrox-3-nitro-phenyl-arsonic acid Arsonic acid,As-(4-hydroxy-3-nitrophenyl)- ROXARSONE(3-nitro-4-hydroxyphenylarsonic acid) 2-NITROPHENYL-4-ARSENIC ACID MIN. 99% 4-HYDROXY-3-NITROBENZENEARSONIC ACID 9 3-NITRO-4-HYDROXY-1-PHENYLARSONIC ACID 3-NITRO-4-HYDROXYPHENYLARSONICACID(ROXARSONE) BENZENEARSONICACID,4-HYDROXY-3-NITRO- 2-Nitrophenol-4-arsonic acid, 4-Hydroxy-3-nitrobenzenearsonic acid 3-NITRO-4-HYDROXYPHENYLARSONIC ACID ROXARSON ROXARSONE NITROPHENOL-4-ARSENIC ACID NITROPHENOLARSONIC ACID (4-hydroxy-3-nitrophenyl)-arsonicaci 2-nitro-1-hydroxybenzene-4-arsonicacid 3-nitro 3-nitro-10 3-nitro-20 3-nitro-4-hydroxybenzenearsonicacid 3-nitro-50 3-nitro-80 4-hydroxy-3-nitro-benzenearsonicaci aklomix-3 Arsonicacid,(4-hydroxy-3-nitrophenyl)- kyselina4-hydroxy-3-nitrofenylarsonova nci-c56508 nitroacid100percent nsc-2101 ren-o-sal reno-sal ristat ROXARSON VETRANAL 4-Hydroxy-3-nitrophenylarsonicAcid> Sparsentan Impurity 33 121-19-7 C6H6AsNO6 HOC6H3NO2AsO3H2 Classes of Metal Compounds As (Arsenic) Compounds Semimetal Compounds Pharmaceutical intermediates MERTHIOLATE Organometallics As (Arsenic) Compounds Classes of Metal Compounds Semimetal Compounds