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4-Benzyloxyindole

CAS No.
20289-26-3
Chemical Name:
4-Benzyloxyindole
Synonyms
NSC 92539;4-BENZYLOXYINDOLE;4-BENZYLOXYLINDOLE;4-Benzyloxyindole>4-BENZYLOXYINDOLE 98%;4-BENZYLOXY-1H-INDOLE;4-Benzyloxyindole,99%;4-Benzyloxyindole ,98%;4-(phenylmethoxy)-1h-indole;4-(Benzyloxy)-1H-indole 98%
CBNumber:
CB4319405
Molecular Formula:
C15H13NO
Molecular Weight:
223.27
MDL Number:
MFCD00047200
MOL File:
20289-26-3.mol
MSDS File:
SDS
Last updated:2023-09-27 13:31:52

4-Benzyloxyindole Properties

Melting point 57-61 °C (lit.)
Boiling point 364.56°C (rough estimate)
Density 1.0707 (rough estimate)
refractive index 1.5500 (estimate)
storage temp. Sealed in dry,Room Temperature
solubility Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly)
form Solid
pka 17.17±0.30(Predicted)
color Beige to Brown
BRN 183150
CAS DataBase Reference 20289-26-3(CAS DataBase Reference)

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P261-P264-P271-P280-P302+P352-P305+P351+P338
Hazard Codes  Xi
Risk Statements  36/37/38
Safety Statements  26-36-37/39
WGK Germany  3
HazardClass  IRRITANT
HS Code  29339990
NFPA 704
1
2 0

4-Benzyloxyindole price More Price(33)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 246212 4-Benzyloxyindole 98% 20289-26-3 1g $30 2023-06-20 Buy
TCI Chemical B2811 4-Benzyloxyindole >98.0%(GC) 20289-26-3 1g $77 2024-03-01 Buy
TCI Chemical B2811 4-Benzyloxyindole >98.0%(GC) 20289-26-3 5g $234 2024-03-01 Buy
Alfa Aesar L17147 4-Benzyloxyindole, 99% 20289-26-3 1g $96.3 2021-12-16 Buy
Alfa Aesar L17147 4-Benzyloxyindole, 99% 20289-26-3 250mg $33.1 2021-12-16 Buy
Product number Packaging Price Buy
246212 1g $30 Buy
B2811 1g $77 Buy
B2811 5g $234 Buy
L17147 1g $96.3 Buy
L17147 250mg $33.1 Buy

4-Benzyloxyindole Chemical Properties,Uses,Production

Chemical Properties

Off-White Crystalline Solid with Few Darker (Brown) Particles

Uses

4-Benzyloxyindole was used in the synthesis of 4-alkyloxy-aminoalkyl indole derivatives.

Uses

Indole derivative as substrate-binding; N297Q and I300V mutants of cytochrome P 450 2A6 display expansion of substrate specificity of cytochrome P 450 2A6 to oxidize substituted indoles

Reactions

4-Benzyloxyindole was used in the synthesis of 4-alkyloxy-aminoalkyl indole derivatives.

  1. Reactant for regioselective synthesis of oxopyrrolidine analogs via iodine-catalyzed Markovnikov addition
  2. Reactant for preparation of indoles by Bartoli reductive cyclization as useful intermediates in medicinal chemistry research
  3. Reactant for synthesis of carbon-11-labeled 4-aryl-4H-chromenes as new PET agents for imaging of apoptosis in cancer
  4. Reactant for preparation of HCV inhibitors.
  5. Reactant for preparation of indol-3-yl tetramethylcyclopropyl ketones as CB2 cannabinoid receptor ligands
  6. Reactant for preparation of 4-aryl-4H-chromenes as apoptosis inducers

Synthesis Reference(s)

Organic Syntheses, Coll. Vol. 7, p. 34, 1990
The Journal of Organic Chemistry, 51, p. 4294, 1986 DOI: 10.1021/jo00372a037
Tetrahedron Letters, 24, p. 4561, 1983 DOI: 10.1016/S0040-4039(00)85955-9

Global( 359)Suppliers
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View Lastest Price from 4-Benzyloxyindole manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
4-Benzyloxyindole pictures 2024-01-11 4-Benzyloxyindole
20289-26-3
US $122.00-1.00 / KG 1KG 99% g-kg-tons, free sample is available Henan Fengda Chemical Co., Ltd
4-Benzyloxyindole pictures 2023-09-27 4-Benzyloxyindole
20289-26-3
US $20.00-1.00 / kg 1kg 0.99 20 tons Hebei Yanxi Chemical Co., Ltd.
4-Benzyloxyindole pictures 2023-09-06 4-Benzyloxyindole
20289-26-3
US $0.00 / KG 1KG 99% 500000kg Hebei Guanlang Biotechnology Co., Ltd.
4-(phenylmethoxy)-1h-indole 4-BENZYLOXY-1H-INDOLE 4-BENZYLOXYINDOLE 4-BENZYLOXYLINDOLE NSC 92539 4-BENZYLOXYINDOLE 98% {[(1H-Indol-4-yl)oxy]methyl}benzene 4-(Benzyloxy)-1H-indole 98% 4-Benzyloxyindole ,98% 1H-Indole, 4-(phenylMethoxy)- 4-Benzyloxyindole,99% 4-Benzyloxyindole 20289-26-3 4-(Phenylmethoxy)-1H-indole 20289-26-3 4-Benzyloxyindole in stock Factory 4-Benzyloxyindole> 20289-26-3 20286-26-3 20289-29-3 Indoles Simple Indoles Building Blocks Heterocyclic Building Blocks Simple Indoles Indole Chiral Compound Aromatics Indole Derivatives Pyrroles & Indoles Building Blocks Heterocyclic Building Blocks Indoles Heterocycle-Indole series blocks IndolesOxindoles Indoles and derivatives Aromatics Compounds Pyrroles & Indoles Indoline & Oxindole Indole Series bc0001