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CCT241161

CAS No.
1163719-91-2
Chemical Name:
CCT241161
Synonyms
CCT241161;1-(5-tert-butyl-2-phenylpyrazol-3-yl)-3-[2-methylsulfanyl-4-[(3-oxo-4H-pyrido[2,3-b]pyrazin-8-yl)oxy]phenyl]urea;N-[4-[(3,4-dihydro-3-oxopyrido[2,3-b]pyrazin-8-yl)oxy]-2-(methylthio)phenyl]-N'-[3-(1,1-dimethylethyl)-1-phenyl-1H-pyrazol-5-yl]-urea;Urea, N-[4-[(3,4-dihydro-3-oxopyrido[2,3-b]pyrazin-8-yl)oxy]-2-(methylthio)phenyl]-N'-[3-(1,1-dimethylethyl)-1-phenyl-1H-pyrazol-5-yl]-
CBNumber:
CB43312274
Molecular Formula:
C28H27N7O3S
Molecular Weight:
541.62
MDL Number:
MOL File:
1163719-91-2.mol
Last updated:2023-09-04 15:50:00

CCT241161 Properties

Density 1.36±0.1 g/cm3(Predicted)
storage temp. Store at -20°C
solubility DMSO: Soluble
form A solid
pka 8.47±0.20(Predicted)

CCT241161 price More Price(6)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Cayman Chemical 25536 CCT241161 ≥98% 1163719-91-2 500μg $68 2024-03-01 Buy
Cayman Chemical 25536 CCT241161 ≥98% 1163719-91-2 1mg $130 2024-03-01 Buy
Cayman Chemical 25536 CCT241161 ≥98% 1163719-91-2 5mg $502 2024-03-01 Buy
Cayman Chemical 25536 CCT241161 ≥98% 1163719-91-2 10mg $869 2024-03-01 Buy
AK Scientific 2404DF CID44132853 1163719-91-2 5mg $626 2021-12-16 Buy
Product number Packaging Price Buy
25536 500μg $68 Buy
25536 1mg $130 Buy
25536 5mg $502 Buy
25536 10mg $869 Buy
2404DF 5mg $626 Buy

CCT241161 Chemical Properties,Uses,Production

Description

CCT241161 is a novel orally available, pan-RAF inhibitor with anti-SRC activity. CCT241161 blocked growth of BRAF-mutant and NRAS-mutant melanoma cells, inhibiting MEK?–ERK, in vitro and in vivo. CCT241161 also prevented growth of xenografts derived from patient tumours with acquired or intrinsic resistance to BRAF and MEK inhibitors. BRAF and MEK inhibitors are effective in BRAF mutant melanoma, but most patients eventually relapse with acquired resistance, and others present intrinsic resistance to these drugs.

CCT241161 Preparation Products And Raw materials

Raw materials

Preparation Products

CCT241161 Suppliers

Global( 13)Suppliers
Supplier Tel Email Country ProdList Advantage
HANGZHOU CLAP TECHNOLOGY CO.,LTD
86-571-88216897,88216896 13588875226 sales@hzclap.com CHINA 6313 58
Shanghai Rechem science Co., Ltd. 21-31433387 15618786686 sales@rechemscience.com China 2972 58
Shanghai Hongye Biotechnology Co. Ltd 400-9205774 sales@glpbio.cn China 6870 58
Suzhou youruike Chemical Pharmaceutical Technology Co., Ltd 15317229551 15151849396@163.com China 1000 58
TargetMol Chemicals Inc. 4008200310 marketing@tsbiochem.com China 24131 58
Shanghai Tachizaki Biomedical Research Center 18014399201 sales@chemlab-tachizaki.com China 2333 58
Yantai Sheng Kai Lun Biological Products Co. , Ltd. 3119594100 mark@sklnchem.cn China 7363 58
Nantong QuanYi Biotechnology Co., Ltd 0513-66337626 18051384581 sales@chemhifuture.com China 3913 58
Nanjing Tengyi Biotechnology Co., Ltd 025-58851786 17714337195 sales@tybiochem.com China 4141 58
Shanghai Yifei Biotechnology Co. , Ltd. 021-65675885 18964387627 customer_service@efebio.com China 8740 58

CCT241161 Spectrum

CCT241161 Urea, N-[4-[(3,4-dihydro-3-oxopyrido[2,3-b]pyrazin-8-yl)oxy]-2-(methylthio)phenyl]-N'-[3-(1,1-dimethylethyl)-1-phenyl-1H-pyrazol-5-yl]- N-[4-[(3,4-dihydro-3-oxopyrido[2,3-b]pyrazin-8-yl)oxy]-2-(methylthio)phenyl]-N'-[3-(1,1-dimethylethyl)-1-phenyl-1H-pyrazol-5-yl]-urea 1-(5-tert-butyl-2-phenylpyrazol-3-yl)-3-[2-methylsulfanyl-4-[(3-oxo-4H-pyrido[2,3-b]pyrazin-8-yl)oxy]phenyl]urea 1163719-91-2 C28H27N7O3S