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CCT241161
- CAS No.
- 1163719-91-2
- Chemical Name:
- CCT241161
- Synonyms
- CCT241161;1-(5-tert-butyl-2-phenylpyrazol-3-yl)-3-[2-methylsulfanyl-4-[(3-oxo-4H-pyrido[2,3-b]pyrazin-8-yl)oxy]phenyl]urea;N-[4-[(3,4-dihydro-3-oxopyrido[2,3-b]pyrazin-8-yl)oxy]-2-(methylthio)phenyl]-N'-[3-(1,1-dimethylethyl)-1-phenyl-1H-pyrazol-5-yl]-urea;Urea, N-[4-[(3,4-dihydro-3-oxopyrido[2,3-b]pyrazin-8-yl)oxy]-2-(methylthio)phenyl]-N'-[3-(1,1-dimethylethyl)-1-phenyl-1H-pyrazol-5-yl]-
- CBNumber:
- CB43312274
- Molecular Formula:
- C28H27N7O3S
- Molecular Weight:
- 541.62
- MDL Number:
- MOL File:
- 1163719-91-2.mol
Last updated:2023-09-04 15:50:00
CCT241161 price More Price(6)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Cayman Chemical | 25536 | CCT241161 ≥98% | 1163719-91-2 | 500μg | $68 | 2024-03-01 | Buy |
Cayman Chemical | 25536 | CCT241161 ≥98% | 1163719-91-2 | 1mg | $130 | 2024-03-01 | Buy |
Cayman Chemical | 25536 | CCT241161 ≥98% | 1163719-91-2 | 5mg | $502 | 2024-03-01 | Buy |
Cayman Chemical | 25536 | CCT241161 ≥98% | 1163719-91-2 | 10mg | $869 | 2024-03-01 | Buy |
AK Scientific | 2404DF | CID44132853 | 1163719-91-2 | 5mg | $626 | 2021-12-16 | Buy |
CCT241161 Chemical Properties,Uses,Production
Description
CCT241161 is a novel orally available, pan-RAF inhibitor with anti-SRC activity. CCT241161 blocked growth of BRAF-mutant and NRAS-mutant melanoma cells, inhibiting MEK?–ERK, in vitro and in vivo. CCT241161 also prevented growth of xenografts derived from patient tumours with acquired or intrinsic resistance to BRAF and MEK inhibitors. BRAF and MEK inhibitors are effective in BRAF mutant melanoma, but most patients eventually relapse with acquired resistance, and others present intrinsic resistance to these drugs.
CCT241161 Preparation Products And Raw materials
Raw materials
Preparation Products
CCT241161 Suppliers
Global( 13)Suppliers
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
HANGZHOU CLAP TECHNOLOGY CO.,LTD | 86-571-88216897,88216896 13588875226 | sales@hzclap.com | CHINA | 6313 | 58 |
Shanghai Rechem science Co., Ltd. | 21-31433387 15618786686 | sales@rechemscience.com | China | 2972 | 58 |
Shanghai Hongye Biotechnology Co. Ltd | 400-9205774 | sales@glpbio.cn | China | 6870 | 58 |
Suzhou youruike Chemical Pharmaceutical Technology Co., Ltd | 15317229551 | 15151849396@163.com | China | 1000 | 58 |
TargetMol Chemicals Inc. | 4008200310 | marketing@tsbiochem.com | China | 24131 | 58 |
Shanghai Tachizaki Biomedical Research Center | 18014399201 | sales@chemlab-tachizaki.com | China | 2333 | 58 |
Yantai Sheng Kai Lun Biological Products Co. , Ltd. | 3119594100 | mark@sklnchem.cn | China | 7363 | 58 |
Nantong QuanYi Biotechnology Co., Ltd | 0513-66337626 18051384581 | sales@chemhifuture.com | China | 3913 | 58 |
Nanjing Tengyi Biotechnology Co., Ltd | 025-58851786 17714337195 | sales@tybiochem.com | China | 4141 | 58 |
Shanghai Yifei Biotechnology Co. , Ltd. | 021-65675885 18964387627 | customer_service@efebio.com | China | 8740 | 58 |
CCT241161
Urea, N-[4-[(3,4-dihydro-3-oxopyrido[2,3-b]pyrazin-8-yl)oxy]-2-(methylthio)phenyl]-N'-[3-(1,1-dimethylethyl)-1-phenyl-1H-pyrazol-5-yl]-
N-[4-[(3,4-dihydro-3-oxopyrido[2,3-b]pyrazin-8-yl)oxy]-2-(methylthio)phenyl]-N'-[3-(1,1-dimethylethyl)-1-phenyl-1H-pyrazol-5-yl]-urea
1-(5-tert-butyl-2-phenylpyrazol-3-yl)-3-[2-methylsulfanyl-4-[(3-oxo-4H-pyrido[2,3-b]pyrazin-8-yl)oxy]phenyl]urea
1163719-91-2
C28H27N7O3S