Fmoc-Asn(Trt)-OH
- CAS No.
- 132388-59-1
- Chemical Name:
- Fmoc-Asn(Trt)-OH
- Synonyms
- FMOC-ASN(TRT)-OH;FMOC-ASN(TRT);FMOC-L-ASN(TRT)-OH;L-Asn(Trt);FMoc-Asn(Tre);Fmoc-N-trityL;PKUMDL-YC-1205;FMOC-ASN(XAN)-OH;FMOC-L-ASN(TRITYL);FMOC-ASPARAGINE(TRT)
- CBNumber:
- CB4331632
- Molecular Formula:
- C38H32N2O5
- Molecular Weight:
- 596.67
- MDL Number:
- MFCD00077049
- MOL File:
- 132388-59-1.mol
- MSDS File:
- SDS
Melting point | 201-204 °C(lit.) |
---|---|
alpha | -16 º (c=1, MeOH) |
Boiling point | 858.1±65.0 °C(Predicted) |
Density | 1.271±0.06 g/cm3(Predicted) |
refractive index | -19 ° (C=1, DMF) |
storage temp. | 2-8°C |
solubility | <0.00005g/l |
pka | 3.79±0.10(Predicted) |
form | powder to crystal |
color | White to Almost white |
optical activity | [α]20/D 15.0±1°, c = 1% in methanol |
BRN | 4343823 |
InChIKey | KJYAFJQCGPUXJY-UUWRZZSWSA-N |
SMILES | C(O)(=O)[C@H](CC(N)=O)N(C(OCC1C2=C(C=CC=C2)C2=C1C=CC=C2)=O)C(C1=CC=CC=C1)(C1=CC=CC=C1)C1=CC=CC=C1 |
CAS DataBase Reference | 132388-59-1(CAS DataBase Reference) |
FDA UNII | 5R94765WYL |
Fmoc-Asn(Trt)-OH price More Price(37)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Sigma-Aldrich | 8.52044 | FMOC-Asn(Trt)-OH N-α-Fmoc-N-?-trityl-L-asparagine Novabiochem? | 132388-59-1 | 25g | $72.8 | 2024-03-01 | Buy |
Sigma-Aldrich | 8.52044 | FMOC-Asn(Trt)-OH N-α-Fmoc-N-?-trityl-L-asparagine Novabiochem? | 132388-59-1 | 100g | $219 | 2024-03-01 | Buy |
Sigma-Aldrich | 8.52044 | FMOC-Asn(Trt)-OH N-α-Fmoc-N-?-trityl-L-asparagine Novabiochem? | 132388-59-1 | 250g | $467 | 2024-03-01 | Buy |
Sigma-Aldrich | 8.52044 | FMOC-Asn(Trt)-OH N-α-Fmoc-N-?-trityl-L-asparagine Novabiochem? | 132388-59-1 | 1kg | $1620 | 2024-03-01 | Buy |
Sigma-Aldrich | 47672 | Fmoc-Asn(Trt)-OH ≥97.0% | 132388-59-1 | 5G | $59.4 | 2024-03-01 | Buy |
Fmoc-Asn(Trt)-OH Chemical Properties,Uses,Production
Description
Fmoc-Asn(Trt)-OH prevents the possibility of the amide side chain from undergoing dehydration side reactions during activation, especially with carbodiimide reagents. Fmoc-Asn(Trt)-OH dissolves readily in all standard peptide synthesis reagents, while Fmoc-Asn-OH is only somewhat soluble in NMP or DMF. The trityl group is removed with TFA. This reaction is usually complete within 1 hour at room temperature, but is slower when the Asn(Trt) residue in at the N-terminal of the peptide. In these cases, the deprotection reaction should be extended to 2 hours.
Chemical Properties
white crystal powde
Uses
Fmoc-Asn(Trt)-OH, is an amino acid derivative used in chemical synthesis and peptide chemistry.
Preparation
Synthesis of Fmoc-Asn(Trt)-OH:
Step 1: Crystallization to form N'-Trityl-L-asparagine crystals.
Step 2: Centrifugation to extract N'-Trityl-L-asparagine crystals.
Step 3: Washing to remove residual starting materials in the synthesis.
Step 4: Extraction to obtain N-Acetyl-L-asparagine.
Step 5: Centrifugation to extract N'-Trityl-L-asparagine.
Step 6: Drying to obtain the final product.
This synthesis method effectively removes residual synthetic materials such as trifluoroacetic acid, maleic anhydride, and epichlorohydrin, which are similar in chemical properties to N-Acetyl-L-asparagine, from the product during the production process. The purification method is simple and the product obtained has high purity.
Fmoc-Asn(Trt)-OH Preparation Products And Raw materials
Raw materials
Preparation Products
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
Lanxi Xingnuo Import and Export Trading Co., Ltd | +86-15888978871 +86-13901546477 | sales@xingnuotraders.com | China | 19 | 58 |
Wuhan senwayer century chemical Co.,Ltd | +undefined-27-86652399 +undefined13627115097 | market02@senwayer.com | China | 874 | 58 |
Hangzhou ICH Biofarm Co., Ltd | +undefined8613073685410 | sales@ichemie.com | China | 985 | 58 |
Chengdu Baishixing Science and Technology Industry Co.,Ltd | +86-15008457246 +86-15008457246 | yuki@cd-bsx.com | China | 53 | 58 |
Sichuan HongRi Pharma-Tech Co.,Ltd | +86-028-64841719 +8618980456393 | daisy@enlaibio.com | China | 1369 | 58 |
Capot Chemical Co.,Ltd. | 571-85586718 +8613336195806 | sales@capotchem.com | China | 29797 | 60 |
Shanghai Daken Advanced Materials Co.,Ltd | +86-371-66670886 | info@dakenam.com | China | 15371 | 58 |
Nanjing ChemLin Chemical Industry Co., Ltd. | 025-83697070 | product@chemlin.com.cn | CHINA | 3012 | 60 |
ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 32480 | 60 |
AB PharmaTech,LLC | 323-480-4688 | United States | 989 | 55 |
View Lastest Price from Fmoc-Asn(Trt)-OH manufacturers
Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
---|---|---|---|---|---|---|---|---|
2024-04-23 | Fmoc-L-Asn(Trt)-OH
132388-59-1
|
US $0.00-0.00 / kg | 1kg | 98% | 1T | Sichuan HongRi Pharma-Tech Co.,Ltd | ||
2023-11-27 | Fmoc-Asn(trt)-OH
132388-59-1
|
US $0.00 / gram | 25gram | 99% HPLC | 25 gram | Wuhan Senwayer Century Chemical Co.,Ltd | ||
2023-11-01 | Fmoc-N-β-trityl-L-asparagine
132388-59-1
|
US $0.00 / Box | 1Box | 99% | 200kg | Hangzhou ICH Biofarm Co., Ltd |
- Fmoc-L-Asn(Trt)-OH
132388-59-1
- US $0.00-0.00 / kg
- 98%
- Sichuan HongRi Pharma-Tech Co.,Ltd
- Fmoc-Asn(trt)-OH
132388-59-1
- US $0.00 / gram
- 99% HPLC
- Wuhan Senwayer Century Chemical Co.,Ltd
- Fmoc-N-β-trityl-L-asparagine
132388-59-1
- US $0.00 / Box
- 99%
- Hangzhou ICH Biofarm Co., Ltd