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Fmoc-Asn(Trt)-OH

CAS No.
132388-59-1
Chemical Name:
Fmoc-Asn(Trt)-OH
Synonyms
FMOC-ASN(TRT)-OH;FMOC-ASN(TRT);FMOC-L-ASN(TRT)-OH;L-Asn(Trt);FMoc-Asn(Tre);Fmoc-N-trityL;PKUMDL-YC-1205;FMOC-ASN(XAN)-OH;FMOC-L-ASN(TRITYL);FMOC-ASPARAGINE(TRT)
CBNumber:
CB4331632
Molecular Formula:
C38H32N2O5
Molecular Weight:
596.67
MDL Number:
MFCD00077049
MOL File:
132388-59-1.mol
MSDS File:
SDS
Last updated:2023-12-07 16:07:34

Fmoc-Asn(Trt)-OH Properties

Melting point 201-204 °C(lit.)
alpha -16 º (c=1, MeOH)
Boiling point 858.1±65.0 °C(Predicted)
Density 1.271±0.06 g/cm3(Predicted)
refractive index -19 ° (C=1, DMF)
storage temp. 2-8°C
solubility <0.00005g/l
pka 3.79±0.10(Predicted)
form powder to crystal
color White to Almost white
optical activity [α]20/D 15.0±1°, c = 1% in methanol
BRN 4343823
InChIKey KJYAFJQCGPUXJY-UUWRZZSWSA-N
SMILES C(O)(=O)[C@H](CC(N)=O)N(C(OCC1C2=C(C=CC=C2)C2=C1C=CC=C2)=O)C(C1=CC=CC=C1)(C1=CC=CC=C1)C1=CC=CC=C1
CAS DataBase Reference 132388-59-1(CAS DataBase Reference)
FDA UNII 5R94765WYL

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS09
Signal word  Warning
Hazard statements  H411
Precautionary statements  P273-P391-P501
Risk Statements  53
Safety Statements  24/25-61
RIDADR  UN 3077 9 / PGIII
WGK Germany  2
3-10
HS Code  2924 29 70
HazardClass  IRRITANT
Toxicity LD50 orally in Rabbit: > 2000 mg/kg
NFPA 704
1
0 0

Fmoc-Asn(Trt)-OH price More Price(37)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 8.52044 FMOC-Asn(Trt)-OH N-α-Fmoc-N-?-trityl-L-asparagine Novabiochem? 132388-59-1 25g $72.8 2024-03-01 Buy
Sigma-Aldrich 8.52044 FMOC-Asn(Trt)-OH N-α-Fmoc-N-?-trityl-L-asparagine Novabiochem? 132388-59-1 100g $219 2024-03-01 Buy
Sigma-Aldrich 8.52044 FMOC-Asn(Trt)-OH N-α-Fmoc-N-?-trityl-L-asparagine Novabiochem? 132388-59-1 250g $467 2024-03-01 Buy
Sigma-Aldrich 8.52044 FMOC-Asn(Trt)-OH N-α-Fmoc-N-?-trityl-L-asparagine Novabiochem? 132388-59-1 1kg $1620 2024-03-01 Buy
Sigma-Aldrich 47672 Fmoc-Asn(Trt)-OH ≥97.0% 132388-59-1 5G $59.4 2024-03-01 Buy
Product number Packaging Price Buy
8.52044 25g $72.8 Buy
8.52044 100g $219 Buy
8.52044 250g $467 Buy
8.52044 1kg $1620 Buy
47672 5G $59.4 Buy

Fmoc-Asn(Trt)-OH Chemical Properties,Uses,Production

Description

Fmoc-Asn(Trt)-OH prevents the possibility of the amide side chain from undergoing dehydration side reactions during activation, especially with carbodiimide reagents. Fmoc-Asn(Trt)-OH dissolves readily in all standard peptide synthesis reagents, while Fmoc-Asn-OH is only somewhat soluble in NMP or DMF. The trityl group is removed with TFA. This reaction is usually complete within 1 hour at room temperature, but is slower when the Asn(Trt) residue in at the N-terminal of the peptide. In these cases, the deprotection reaction should be extended to 2 hours.

Chemical Properties

white crystal powde

Uses

Fmoc-Asn(Trt)-OH, is an amino acid derivative used in chemical synthesis and peptide chemistry.

Preparation

Synthesis of Fmoc-Asn(Trt)-OH:
Step 1: Crystallization to form N'-Trityl-L-asparagine crystals.
Step 2: Centrifugation to extract N'-Trityl-L-asparagine crystals.
Step 3: Washing to remove residual starting materials in the synthesis.
Step 4: Extraction to obtain N-Acetyl-L-asparagine.
Step 5: Centrifugation to extract N'-Trityl-L-asparagine.
Step 6: Drying to obtain the final product.
This synthesis method effectively removes residual synthetic materials such as trifluoroacetic acid, maleic anhydride, and epichlorohydrin, which are similar in chemical properties to N-Acetyl-L-asparagine, from the product during the production process. The purification method is simple and the product obtained has high purity.

Fmoc-Asn(Trt)-OH Preparation Products And Raw materials

Global( 431)Suppliers
Supplier Tel Email Country ProdList Advantage
Lanxi Xingnuo Import and Export Trading Co., Ltd
+86-15888978871 +86-13901546477 sales@xingnuotraders.com China 19 58
Wuhan senwayer century chemical Co.,Ltd
+undefined-27-86652399 +undefined13627115097 market02@senwayer.com China 874 58
Hangzhou ICH Biofarm Co., Ltd
+undefined8613073685410 sales@ichemie.com China 985 58
Chengdu Baishixing Science and Technology Industry Co.,Ltd
+86-15008457246 +86-15008457246 yuki@cd-bsx.com China 53 58
Sichuan HongRi Pharma-Tech Co.,Ltd
+86-028-64841719 +8618980456393 daisy@enlaibio.com China 1369 58
Capot Chemical Co.,Ltd.
571-85586718 +8613336195806 sales@capotchem.com China 29797 60
Shanghai Daken Advanced Materials Co.,Ltd
+86-371-66670886 info@dakenam.com China 15371 58
Nanjing ChemLin Chemical Industry Co., Ltd.
025-83697070 product@chemlin.com.cn CHINA 3012 60
ATK CHEMICAL COMPANY LIMITED
+undefined-21-51877795 ivan@atkchemical.com China 32480 60
AB PharmaTech,LLC
323-480-4688 United States 989 55

View Lastest Price from Fmoc-Asn(Trt)-OH manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Fmoc-L-Asn(Trt)-OH pictures 2024-04-23 Fmoc-L-Asn(Trt)-OH
132388-59-1
US $0.00-0.00 / kg 1kg 98% 1T Sichuan HongRi Pharma-Tech Co.,Ltd
 Fmoc-Asn(trt)-OH pictures 2023-11-27 Fmoc-Asn(trt)-OH
132388-59-1
US $0.00 / gram 25gram 99% HPLC 25 gram Wuhan Senwayer Century Chemical Co.,Ltd
Fmoc-N-β-trityl-L-asparagine pictures 2023-11-01 Fmoc-N-β-trityl-L-asparagine
132388-59-1
US $0.00 / Box 1Box 99% 200kg Hangzhou ICH Biofarm Co., Ltd
  •  Fmoc-Asn(trt)-OH pictures
  • Fmoc-Asn(trt)-OH
    132388-59-1
  • US $0.00 / gram
  • 99% HPLC
  • Wuhan Senwayer Century Chemical Co.,Ltd
N-ALPHA-FMOC-N-GAMMA-TRITYL-L-ASPARAGINE FMOC-ASPARAGINE(TRT) FMOC-ASN(XAN)-OH FMOC-L-ASN(TRITYL) FMOC-L-ASPARGINE(TRITYL) FMOC-L-ASPARAGINE(TRITYL) FMOC-L-ASPARAGINE (TRT) FMOC-N-GAMMA-XANTHYL-L-ASPARAGINE Nalpha-fluorenylmethoxycarbonyl-Ngamma-trityl-L-asparagine Nα-(9-Fluorenylmethoxycarbonyl)-Nγ-trityl-L-asparagine, Nα-Fmoc-Nγ-trityl-L-asparagine N-(9-Fluorenylmethyloxycarbonyl)-N-trityl-L-asparagine ,98% Fmoc-L-Asparagine(Trt)-OH Fmoc-N-trityl-L-asparagine ,98% Fmoc-N-trityl-L-aspa Fmoc-Asparagine(Trt)-OH L-ASPARAGINE-N-FMOC, N-BETA-TRITYL Nalpha-Fmoc-Ngamma-trityl-L-asparagine Fmoc-Asn(Trt)-OH N^a-FMoc-N^y-trityl-L-asparagine, 97% FMoc-N-trityl-L-aspaD23-Ragine (S)-2-((((9H-Fluoren-9-yl)Methoxy)carbonyl)aMino)-4-oxo-4-(tritylaMino)butanoic acid FMoc-Asn(Tre) Fmoc-Asn(Trt)-OH >=97.0% (sum of enantiomers, HPLC) Fmoc-Asn(Trt)-OH(CAS:132388-59-1) FMOC-NG-TRITYL-L-ASPARAGINE FMOC-N-GAMMA-TRITYL-L-ASPARAGINE FMOC-N-TRITYL-L-ASPARAGINE FMOC-N-BETA-TRITYL-L-ASPARAGINE Nα-(9-Fluorenylmethoxycarbonyl)-Nγ-trityl-L-asparagine Na-(9-Fluorenyl Methoxy Carbonyl)-Ng-Trityl-L-Asparagine na-fmoc-N-gamma-trityl-L-asparagine N-alpha-(9-fluorenylmethoxycarbonyl)-N-gamma-trit N-α-Fmoc-N-γ-trityl-L-asparagine N-ALPHA-(9-FLUORENYLMETHOXYCARBONYL)-N-& FMOC-N-TRITYL-L-ASPARAGINE 97+% N-FMOC-N4-TRITYL-L-ASPARAGINE N-(9-Fluorenylmethoxycarbonyl)-N-trityl-L-aspara L-Asparagine N-|beta|-Trityl-15N2-N-alpha-FMOC L-Asparagin, N(2)-((9H-fluoren-9-ylmethoxy)carbonyl)- N-(triphenylmethyl)- N2-[(9H-FLUOREN-9-YLMETHOXY)CARBONYL]-N-(TRIPHENYLMETHYL)-L-ASPARAGINE N-.ALPHA.-FMOC-N-.GAMMA.-XANTHYL-L-ASPARAGINE N-α-Fmoc-β-trityl-L-asparagine L-Asparagine N-β-Trityl-15N2-N-α-FMOC Nα-[(9H-Fluoren-9-ylmethoxy)carbonyl]-Nγ-trityl-L-asparagine Nα-Fmoc-Nγ-trityl-L-asparagine≥ 99.7% (HPLC, Chiral purity) N-FMOC-L-ASN(TRT)-OH N-(9-FLUORENYL METHOXY CARBONYL)-N-TRITYL-L-ASPARAGINE N-ALPHA-[(9H-FLUOREN-9-YLMETHOXY)CARBONYL]-N-GAMMA-TRITYL-L-ASPARAGINE N-ALPHA-(9-FLUORENYLMETHYLOXYCARBONYL)-N-BETA-TRITYL-L-ASPARAGINE N-ALPHA-9-FLUORENYLMETHOXYCARBONYL-N-OMEGA-TRITYL-L-ASPARAGINE NALPHA-(9-FLUORENYLMETHOXYCARBONYL)-NR-TRITYL-L-ASPARAGINE N-ALPHA-(9-FLUORENYLMETHOXYCARBONYL)-N-GAMMA-TRITYL-L-ASPARAGINE N-ALPHA-(9-FLUORENYLMETHOXYCARBONYL)-N-BETA-TRITYL-L-ASPARAGINE N-ALPHA-(9-FLUORENYLMETHOXYCARBONYL)-N-BETA-XANTHYL-L-ASPARAGINE N ALPHA-T-BUTOXYCARBONYL-N GAMMA-TRITYL-L-ASPARAGINE N-ALPHA-FMOC-N-BETA-TRITYL-L-ASPARAGINE (2S)-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-3-[(triphenylmethyl)carbamoyl]propanoic acid 4-[[9H-fluoren-9-ylmethoxy(oxo)methyl]amino]-4-oxo-2-[(triphenylmethyl)amino]butanoic acid Nα-[(9H-Fluoren-9-ylmethoxy)carbonyl]-Nγ-trityl-L-asparagine>