O-GLYCOSIDASE
- CAS No.
- 9032-92-2
- Chemical Name:
- O-GLYCOSIDASE
- Synonyms
- O-Glycanase;EC 3.2.1.97;O-GLYCOSIDASE;O-GLYCAN PEPTIDE HYDROLASE;endo-α-n-acetylgalactosaminidase;O-GLYCOSIDASE, EXPRESSED IN E. COLI;ENDO-ALPHA-N-ACETYLGALACTOSAMINIDASE;o-glycosidase from streptococcus pneumoniae;Endo-α-N-acetylgalactosaminidase, O-Glycanase;O-Glycosidase from Streptococcus pneumoniae, Recombinant
- CBNumber:
- CB4337902
- Molecular Formula:
- Molecular Weight:
- 0
- MDL Number:
- MFCD00131003
- MOL File:
- Mol file
O-GLYCOSIDASE price More Price(1)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | G1163 | O-Glycosidase from Streptococcus pneumoniae recombinant, expressed in E. coli, buffered aqueous solution | 9032-92-2 | 0.04unit | $625 | 2024-03-01 | Buy |
| Product number | Packaging | Price | Buy |
|---|---|---|---|
| G1163 | 0.04unit | $625 | Buy |
O-GLYCOSIDASE Chemical Properties,Uses,Production
Uses
O-Glycosidase is used to release the Gal-β(1,3)-GaINAc unit from O-glycans (glycoproteins or glycopeptides). Bindings to serine as well as to threonine are hydrolyzed. Substituents at the disaccharide (e.g., sialic acid) prevent the hydrolysis and, therefore, have to be removed chemically or enzymatically (e.g., with neuraminidase from Arthrobacter or from Vibrio cholerae).
O-Glycosidase has been used to selectively deglycosylated chondroitin sulfate proteoglycans (CSPGs).
General Description
O-Glycan-peptide hydrolase
O-Glycopeptide endo-D-galactosyl-N-acetyl-α-galactosamino hydrolase
O-Glycosidase is isolated from the culture filtrate of Diplococcus pneumoniae
Biochem/physiol Actions
Releases unsubstituted Ser- and Thr-linked β-Gal-(1→3)-α-GalNAc (Core 1 type O-glycan) from glycoproteins. Substitutions of the disaccharide core with sialic acid, lactosamine (galactose-N-acetyl glucosamine), or fucose will block hydrolysis and prevent the liberation of the oligosaccharide from the protein. Pretreament with glycolytic enzymes to remove substituent saccharides from the O-glycan may be needed prior to cleavage using O-glycosidase..
O-GLYCOSIDASE Preparation Products And Raw materials
Raw materials
Preparation Products
O-GLYCOSIDASE Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Creative Enzymes | 1-516-855-7709 | info@creative-enzymes.com | United States | 8748 | 58 |
| Career Henan Chemica Co | +86-0371-86658258 15093356674; | laboratory@coreychem.com | China | 30255 | 58 |
| Shanghai Acmec Biochemical Technology Co., Ltd. | +undefined18621343501 | product@acmec-e.com | China | 33349 | 58 |
| Aladdin Scientific | +1-833-552-7181 | sales@aladdinsci.com | United States | 52927 | 58 |
| Sigma-Aldrich | 021-61415566 800-8193336 | orderCN@merckgroup.com | China | 51471 | 80 |
| Guangzhou Tomums Life Science Co., Ltd. | 020-31155029 18902330969 | sales@tomums.cn | China | 4698 | 58 |
| Shanghai jingkang bioengineering co., ltd. | 021-54721350 13524668266 | 2881505714@qq.com | China | 7878 | 58 |
| Shanghai Kanglang Biotechnology Co., Ltd. | 021-61998208 18217752821 | sales@klbio.cn | China | 9617 | 58 |
| Aleshan (Guangzhou) Biotechnology Co., Ltd | 18636736628 | Araratbio@163.com | China | 3342 | 58 |
| Shaanxi Dideu Medichem Co. Ltd | 029-81124267 15229202216 | 1073@dideu.com | China | 10011 | 58 |
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