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FUBERIDAZOLE

CAS No.
3878-19-1
Chemical Name:
FUBERIDAZOLE
Synonyms
PF 7402;B-33172;Voronit;bay33172;Voronite;wvii/117;NSC 72670;BAY 33172;Furidazol;W Vii/117
CBNumber:
CB4345158
Molecular Formula:
C11H8N2O
Molecular Weight:
184.19
MDL Number:
MFCD00055496
MOL File:
3878-19-1.mol
MSDS File:
SDS
Last updated:2024-03-14 15:18:26

FUBERIDAZOLE Properties

Melting point 310-312℃
Boiling point 318.14°C (rough estimate)
Density 1.1820 (rough estimate)
vapor pressure <1 x 10-3Pa (20 °C)
refractive index 1.5300 (estimate)
storage temp. 0-6°C
solubility DMSO (Slightly), Methanol (Slightly)
pka 4.6 (base)
Water Solubility 200 mg l-1 (pH 4), 71 mg l-1 (pH 7) at 20 °C
color Off-White to Pale Beige
BRN 153833
LogP 2.670
CAS DataBase Reference 3878-19-1(CAS DataBase Reference)
EWG's Food Scores 1
FDA UNII RXD450F6C7
EPA Substance Registry System Fuberidazole (3878-19-1)

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictogramsGHS hazard pictogramsGHS hazard pictograms
GHS06,GHS08,GHS09
Signal word  Danger
Hazard statements  H302-H311-H317-H330-H351-H373-H410
Precautionary statements  P201-P273-P280-P301+P312-P302+P352+P312-P304+P340+P310
Hazard Codes  Xn,N,T
Risk Statements  22-50/53-23-21-48/22-43-40-21/22
Safety Statements  22-60-61-45-36/37
RIDADR  2588
WGK Germany  3
RTECS  DD9010000
HazardClass  6.1(b)
PackingGroup  III
HS Code  29339900

FUBERIDAZOLE price More Price(12)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 45515 Fuberidazole PESTANAL 3878-19-1 250mg $108 2024-03-01 Buy
TRC F805500 Fuberidazole 3878-19-1 5mg $45 2021-12-16 Buy
TRC F805500 Fuberidazole 3878-19-1 10mg $60 2021-12-16 Buy
TRC F805500 Fuberidazole 3878-19-1 50mg $150 2021-12-16 Buy
Matrix Scientific 077285 2-(2-Furyl)-1H-benzimidazole 3878-19-1 1g $158 2021-12-16 Buy
Product number Packaging Price Buy
45515 250mg $108 Buy
F805500 5mg $45 Buy
F805500 10mg $60 Buy
F805500 50mg $150 Buy
077285 1g $158 Buy

FUBERIDAZOLE Chemical Properties,Uses,Production

Description

Fuberidazole is a crystalline powder.Molecular weight=184.21; Melting point=285℃(decomposition). Hazard Identification (based on NFPA-704 M Rating System): Health 2, Flammability 1,Reactivity 0. Very slightly soluble in water.

Chemical Properties

Fuberidazole is a crystalline powder.

Uses

Fuberidazole is a systemic fungicide used in cereal seed dressing to control a variety of soil and seed borne diseases caused by Fusarium spp. It is also used as an anthelmintic and an inhibitor of enteroviruses.

Uses

Fuberidazole is a benzimidazole based fungicide used as a fungicidal seed treatment of barley.

Definition

ChEBI: A ring assembly consisting of benzimidazole substituted at position 2 by a 2-furyl group. A fungicide used as a seed treatment to control Fusarium spp. in cereals.

General Description

Crystalline powder. Used in cereal seed dressing and fungicidal non-mercurial seed dressing with special action against fusarium. Not registered as a pesticide in the U.S.

Reactivity Profile

FUBERIDAZOLE is a benzimidazole and behaves as an amine. Amines are chemical bases. They neutralize acids to form salts plus water. These acid-base reactions are exothermic. The amount of heat that is evolved per mole of amine in a neutralization is largely independent of the strength of the amine as a base. Amines may be incompatible with isocyanates, halogenated organics, peroxides, phenols (acidic), epoxides, anhydrides, and acid halides. Flammable gaseous hydrogen is generated by amines in combination with strong reducing agents, such as hydrides

Health Hazard

FUBERIDAZOLE is classified as moderately toxic. Its probable oral lethal dose in humans is 0.5-5 g/kg or between 1 ounce and 1 pint for a150 lb. person.

Fire Hazard

When heated to decomposition, FUBERIDAZOLE emits toxic fumes of nitrogen oxides.

Agricultural Uses

Fungicide, Seed treatment: Uses include cereal seed dressing; and fungicidal non-mercurial seed dressing with special action against fusarium. Not registered as a pesticide for use in the U.S. Registered for use in EU countries.

Trade name

BAYCOR®; BAYER 33172®; BAYTAN®; BAYTAN® FS; ICI BAYTAN®; NEOVORONIT®; SIBUTOL®; SIBUTROL®; VORONIT®; VORONITE®; W VII/117®

Potential Exposure

Fuberidazole, a benzimidazole, uses include cereal seed dressing; and fungicidal, nonmercurial seed dressing with special action against fusarium. Not reg istered as a pesticide in the U.S.A.

First aid

: If this chemical gets into the eyes, remove anycontact lenses at once and irrigate immediately for at least15 min, occasionally lifting upper and lower lids. Seek medical attention immediately. If this chemical contacts theskin, remove contaminated clothing and wash immediatelywith soap and water. Seek medical attention immediately. Ifthis chemical has been inhaled, remove from exposure,begin rescue breathing (using universal precautions, including resuscitation mask) if breathing has stopped and CPR ifheart action has stopped. Transfer promptly to a medicalfacility. When this chemical has been swallowed, get medical attention. Give large quantities of water and inducevomiting. Do not make an unconscious person vomit.

Metabolic pathway

Limited information is available describing the degradation and metabolic fate of fuberidazole. Information presented below was abstracted mainly from the Pesticide Manual (PM). The major degradation pathways observed include rearrangement of the fury1 moiety under UV light irradiation, hydrolysis and hydroxylation reactions in mammalian systems.

storage

Color Code—Blue: Health Hazard/Poison: Storein a secure poison location. Prior to working with thischemical you should be trained on its proper handling andstorage. Store in tightly closed containers in a cool, wellventilated area.

Shipping

UN2588 Pesticides, solid, toxic, Hazard Class: 6.1; Labels: 6.1-Poisonous materials, Technical Name Required. UN2811 Toxic solids, organic, n.o.s., Hazard Class: 6.1; Labels: 6.1-Poisonous materials, Technical Name Required.

Degradation

Fuberidazole (1) is stable to hydrolysis in pure water and sensitive to light with a half-life (DT50) of ca. 15 min (PM).
Photolysis (at 313 nm using a high pressure Hg lamp) of fuberidazole was much faster for the protonated state as compared to the neutral state (Melo et al., 1994), probably via a cyclopropanyl ketone intermediate (see Scheme 1). Reaction of this intermediate with either water or methanol yielded benzimidazole-2-carboxylic acid (2) or its methyl ester (3), methyl 4-oxo-4-(benzimidazol-2-yl)crotonate( 4, both the cis and trans isomers) and 1-methoxybenzimidazole (5) as major degradates (Melo et al., 1992). Benzimidazole (6) and 2,2'-bibenzimidazole (7) were also detected.

Incompatibilities

Incompatible with acid halides, anhydrides, epoxides, halogenated organics, isocyanates, peroxides, phenols (acidic).

Waste Disposal

In accordance with 40CFR 165 recommendations for the disposal of pesticides and pesticide containers. Must be disposed properly by follow ing package label directions or by contacting your local or federal environmental control agency, or by contacting your regional EPA office.

98-01-1
95-54-5
3878-19-1
Synthesis of FUBERIDAZOLE from Furfural and o-Phenylenediamine
Global( 97)Suppliers
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