ChemicalBook >> CAS DataBase List >>2-[2-(5-BROMO-1H-INDOL-3-YL)ETHYL]-3-[3-(1-METHYLETHOXY)PHENYL]-4-(3H)-QUINAZOLINONE

2-[2-(5-BROMO-1H-INDOL-3-YL)ETHYL]-3-[3-(1-METHYLETHOXY)PHENYL]-4-(3H)-QUINAZOLINONE

CAS No.
133040-77-4
Chemical Name:
2-[2-(5-BROMO-1H-INDOL-3-YL)ETHYL]-3-[3-(1-METHYLETHOXY)PHENYL]-4-(3H)-QUINAZOLINONE
Synonyms
LY 225910;2-(2-(5-BroMo-1H-indol-3-yl)ethyl)-3-(3-isopropoxyphenyl)quinazolin-4(3H)-one;2-[2-(5-Bromo-1H-indol-3-yl)-ethyl]-3-(3-isopropoxy-phenyl)-3H-quinazolin-4-one;2-(2-(5-Bromo-(1H)-indol-3-yl)ethyl)-3-(3-(1-methylethoxy)phenyl)-4-(3H)-quinazoline;2-[2-(5-BROMO-1H-INDOL-3-YL)ETHYL]-3-[3-(1-METHYLETHOXY)PHENYL]-4-(3H)-QUINAZOLINONE;4(3H)-Quinazolinone, 2-[2-(5-bromo-1H-indol-3-yl)ethyl]-3-[3-(1-methylethoxy)phenyl]-
CBNumber:
CB4349752
Molecular Formula:
C27H24BrN3O2
Molecular Weight:
502.4
MDL Number:
MFCD00907856
MOL File:
133040-77-4.mol
Last updated:2023-06-30 15:45:59

2-[2-(5-BROMO-1H-INDOL-3-YL)ETHYL]-3-[3-(1-METHYLETHOXY)PHENYL]-4-(3H)-QUINAZOLINONE Properties

Flash point 337 - 405℃
storage temp. Desiccate at -20°C
solubility DMSO: >20mg/mL
form powder
color off-white

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS06
Signal word  Danger
Hazard statements  H301-H413
Precautionary statements  P264-P270-P273-P301+P310-P405-P501
Hazard Codes  Xn
Risk Statements  22
RIDADR  UN 2811 6.1 / PGIII
WGK Germany  3

2-[2-(5-BROMO-1H-INDOL-3-YL)ETHYL]-3-[3-(1-METHYLETHOXY)PHENYL]-4-(3H)-QUINAZOLINONE price More Price(9)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich L2545 LY225910 ≥98% (HPLC) 133040-77-4 25mg $489 2024-03-01 Buy
Sigma-Aldrich L2545 LY225910 ≥98% (HPLC) 133040-77-4 5mg $137 2022-05-15 Buy
Tocris 1018 LY225910 133040-77-4 10 $115 2021-12-16 Buy
Tocris 1018 LY225910 133040-77-4 50 $479 2021-12-16 Buy
TRC L503145 LY225910 133040-77-4 10mg $185 2021-12-16 Buy
Product number Packaging Price Buy
L2545 25mg $489 Buy
L2545 5mg $137 Buy
1018 10 $115 Buy
1018 50 $479 Buy
L503145 10mg $185 Buy

2-[2-(5-BROMO-1H-INDOL-3-YL)ETHYL]-3-[3-(1-METHYLETHOXY)PHENYL]-4-(3H)-QUINAZOLINONE Chemical Properties,Uses,Production

Uses

LY 225910 is a potent CCK-BR antagonist.

Definition

ChEBI: 2-[2-(5-bromo-1H-indol-3-yl)ethyl]-3-(3-propan-2-yloxyphenyl)-4-quinazolinone is a member of quinazolines.

Biological Activity

Potent CCK 2 receptor antagonist (IC 50 = 9.3 nM for inhibition of 125 I-labeled CCK-8 sulfate binding at mouse brain membranes).

storage

Desiccate at -20°C

2-[2-(5-BROMO-1H-INDOL-3-YL)ETHYL]-3-[3-(1-METHYLETHOXY)PHENYL]-4-(3H)-QUINAZOLINONE Preparation Products And Raw materials

Raw materials

Preparation Products

2-[2-(5-BROMO-1H-INDOL-3-YL)ETHYL]-3-[3-(1-METHYLETHOXY)PHENYL]-4-(3H)-QUINAZOLINONE Suppliers

Global( 32)Suppliers
Supplier Tel Email Country ProdList Advantage
Alchem Pharmtech,Inc.
8485655694 sales@alchempharmtech.com United States 63711 58
TargetMol Chemicals Inc.
+1-781-999-5354 +1-00000000000 marketing@targetmol.com United States 19892 58
Aladdin Scientific
+1-833-552-7181 sales@aladdinsci.com United States 52927 58
3B Pharmachem (Wuhan) International Co.,Ltd. 821-50328103-801 18930552037 3bsc@sina.com China 15848 69
SynAsst Chemical. 021-60343070 China 12742 55
EMMX Biotechnology LLC 888-539-0666 info@emmx.com United States 8449 60
BOC Sciences -- info@bocsci.com USA 0 65
Shanghai Haohong Pharmaceutical Co., Ltd. 400-400-8210725 4008210725 malulu@leyan.com China 55023 58
Energy Chemical 021-58432009 400-005-6266 marketing1@energy-chemical.com China 44894 58
TargetMol Chemicals Inc. 4008200310 marketing@tsbiochem.com China 24131 58
LY 225910 2-[2-(5-BROMO-1H-INDOL-3-YL)ETHYL]-3-[3-(1-METHYLETHOXY)PHENYL]-4-(3H)-QUINAZOLINONE 2-(2-(5-Bromo-(1H)-indol-3-yl)ethyl)-3-(3-(1-methylethoxy)phenyl)-4-(3H)-quinazoline 2-(2-(5-BroMo-1H-indol-3-yl)ethyl)-3-(3-isopropoxyphenyl)quinazolin-4(3H)-one 2-[2-(5-Bromo-1H-indol-3-yl)-ethyl]-3-(3-isopropoxy-phenyl)-3H-quinazolin-4-one 4(3H)-Quinazolinone, 2-[2-(5-bromo-1H-indol-3-yl)ethyl]-3-[3-(1-methylethoxy)phenyl]- 133040-77-4 C27H24BrN3O2