ANTI-BETA-CATENIN
- CAS No.
- Chemical Name:
- ANTI-BETA-CATENIN
- Synonyms
- ANTI-BETA-CATENIN;ANTI-HUMAN BETA-CATENIN;ANTI-BETA-CATENIN (CORE);Monoclonal Anti-β-Catenin;DEPHOSPHO, AMINO ACIDS 27-37;ANTI-BETA-CATENIN (NT/EXON 2);MONOCLONAL ANTIBODY TO BETA-CATENIN;MONOCLONAL ANTI-BETA-CATENIN, CLONE 6F9;MONOCLONAL ANTI-BETA-CATENIN, CLONE 15B8;Monoclonal Anti-β-Catenin antibody produced in mouse
- CBNumber:
- CB4351678
- Molecular Formula:
- Molecular Weight:
- 0
- MDL Number:
- MFCD00282178
- MOL File:
- Mol file
ANTI-BETA-CATENIN price More Price(3)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Sigma-Aldrich | C7207 | Monoclonal Anti-β-Catenin antibody produced in mouse clone 15B8, ascites fluid | 100μL | $499 | 2024-03-01 | Buy | |
Sigma-Aldrich | C7207 | Monoclonal Anti-β-Catenin antibody produced in mouse clone 15B8, ascites fluid | 0.2ML | $657 | 2024-03-01 | Buy | |
Sigma-Aldrich | C7082 | Monoclonal Anti-β-Catenin antibody produced in mouse clone 6F9, ascites fluid | 0.2mL | $198.8 | 2024-03-01 | Buy |
ANTI-BETA-CATENIN Chemical Properties,Uses,Production
Uses
Monoclonal Anti-β-Catenin antibody produced in mouse has been used in:
- immunohistochemistry
- immunofluorescence
- immunoblotting
Uses
Monoclonal Anti-β-Catenin antibody produced in mouse has been used:
- immunoblotting
- immunohistochemistry
- immunolabeling
- immunofluorescence
- immunocytochemical staining
General Description
Monoclonal Anti-β-Catenin (mouse IgG1 isotype) is derived from the 15B8 hybridoma produced by the fusion of mouse myeloma cells and splenocytes from BALB/c mice. β-catenin belongs to the armadillo family and comprises the N-terminal region with 12 imperfect repeats?and a conserved C-terminal region. The locus 3p22.1 in the human chromosome harbors β-catenin gene. β-catenin shares 70% sequence identity to a protein encoded by Drosophila armadillo, a segment polarity gene. Both armadillo and β-catenin share considerable homology with plakoglobin, which has been proposed to be γ-catenin.
Biochem/physiol Actions
β-catenin is a prime component of the wingless (Wnt) pathway and plays a key role in gene expression during development. The homology between β-catenin and armadillo raised the possibility that β-catenin has a developmental signaling role in vertebrates. β-catenin mediates the interaction of the E-cadherin-catenin complex with the epidermal growth factor (EGF) receptor. β-catenin and plakoglobin are substrates for tyrosine phosphorylation following EGF stimulation of cells. β-catenin also associates with the tumor suppressor protein adenomatous polyposis coli (APC). Monoclonal antibody reacting specifically with β-catenin is an essential tool in defining the interactions and distributions of β-catenin and its relationships with other catenins and cadherins in various cells and tissues.
ANTI-BETA-CATENIN Preparation Products And Raw materials
Raw materials
Preparation Products
ANTI-BETA-CATENIN Suppliers
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
Sigma-Aldrich | 021-61415566 800-8193336 | orderCN@merckgroup.com | China | 51471 | 80 |
Shanghai Yiyan Biotechnology Co. , Ltd. | 021-69985186 13611928337 | 3427709316@qq.com | China | 7984 | 58 |
Supplier | Advantage |
---|---|
Sigma-Aldrich | 80 |
Shanghai Yiyan Biotechnology Co. , Ltd. | 58 |