Elemicin
- CAS No.
- 487-11-6
- Chemical Name:
- Elemicin
- Synonyms
- Elemicine;1,2,3-trimethoxy-5-prop-2-enylbenzene;5-ALLYL-1,2,3-TRIMETHOXYBENZENE;elemin;ELEMICIN;ELIMICIN;Elemicin, 10 mM in DMSO;3,4,5-Trimethoxyallylbenzene;5-allyl-1,2,3-trimethoxy-benzen;4-allyl-1,2,6-trimethoxybenzene
- CBNumber:
- CB4352387
- Molecular Formula:
- C12H16O3
- Molecular Weight:
- 208.25
- MDL Number:
- MFCD01656688
- MOL File:
- 487-11-6.mol
- MSDS File:
- SDS
| Product description | Number | Pack Size | Price |
| Elemicin phyproof® Reference Substance | PHL22469 | 1 unit | $301 |
| Elemicin | 29394 | 250mg | $44 |
| Elemicin | 29394 | 500mg | $84 |
| Elemicin | 29394 | 1g | $155 |
| Elemicin | E501020 | 1g | $120 |
| More product size | |||
| Boiling point | 152-156 °C |
|---|---|
| Density | 1.0630 g/cm3 |
| storage temp. | Amber Vial, -20°C Freezer |
| solubility | Chloroform (Slightly), Ethyl Acetate (Slightly) |
| form | Oil |
| color | Colourless |
| Odor | at 100.00 %. spice flower |
| Odor Type | spicy |
| Stability | Light Sensitive |
| Major Application |
food and beverages pharmaceutical |
| InChI | InChI=1S/C12H16O3/c1-5-6-9-7-10(13-2)12(15-4)11(8-9)14-3/h5,7-8H,1,6H2,2-4H3 |
| InChIKey | BPLQKQKXWHCZSS-UHFFFAOYSA-N |
| SMILES | C1(OC)=CC(CC=C)=CC(OC)=C1OC |
| LogP | 2.298 (est) |
| EWG's Food Scores | 1 |
| FDA UNII | HSZ191AKAN |
| NIST Chemistry Reference | Benzene, 1,2,3-trimethoxy-5-(2-propenyl)-(487-11-6) |
| UNSPSC Code | 12352200 |
| NACRES | NA.24 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H302-H315-H319-H335 | |||||||||
| Precautionary statements | P261-P280-P301+P312-P302+P352-P305+P351+P338 | |||||||||
| WGK Germany | WGK 3 | |||||||||
| HS Code | 2909309090 | |||||||||
| Storage Class | 10 - Combustible liquids | |||||||||
| NFPA 704 |
|
Elemicin price More Price(33)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | PHL22469 | Elemicin phyproof® Reference Substance | 487-11-6 | 1 unit | $301 | 2025-07-31 | Buy |
| Cayman Chemical | 29394 | Elemicin | 487-11-6 | 250mg | $44 | 2024-03-01 | Buy |
| Cayman Chemical | 29394 | Elemicin | 487-11-6 | 500mg | $84 | 2024-03-01 | Buy |
| Cayman Chemical | 29394 | Elemicin | 487-11-6 | 1g | $155 | 2024-03-01 | Buy |
| TRC | E501020 | Elemicin | 487-11-6 | 1g | $120 | 2021-12-16 | Buy |
Elemicin Chemical Properties,Uses,Production
Description
Elemicin is a trioxygenated phenylpropane that has been found in A. dracunculus. It is active against S. aureus, B. subtilis, and C. albicans (MICs = 600, 2,500, and 1,000 mg/L, respectively) but not E. coli, K. pneumoniae, P. aeruginosa (MICs = >8,000 mg/L for all), or L. monocytogenes (MIC = >3,000 mg/L). Elemicin is toxic to mice following metabolic activation to 1’-hydroxyelemicin by the cytochrome P450 (CYP) isoforms CYP1A1 and CYP1A2. It increases plasma and hepatic triglyceride levels, decreases stearoyl-CoA desaturase 1 (Scd1) expression, and induces hepatomegaly in mice when administered at a dose of 500 mg/kg per day for three weeks.
Chemical Properties
Clear Colorless Oil
Uses
A constituent of the essential oil of nutmeg and is responsible for the psychoactive effects of nutmeg. Also a minor constituent of the oleoresin and essential oil of Manila elemi (Canarium luzonicum). Exhibits anticholinergic-like effects in humans.
Definition
ChEBI: Elemicin is an olefinic compound.
Synthesis
Prod. :
1) by isolation from Elemi oil (high-boiling
fractions).
2) from Dimcthylpyrogallol plus Allyl bromide,
via 2,6-Dimethyl pyrogallol allylether.
This is heated in a Claisen-rearrangement
reaction to yield 4-Hydroxy-3,5-dimethoxy
allylbenzene. The latter is methylated to
yield Elemicine.
3) From Eugenol via 5-Hydroxyeugenol.
target
Antifection
References
[1] A. PAULI K K. Antimicrobial Properties of Volatile Phenylpropanes[J]. Natural Product Communications, 2010, 122 1. DOI: 10.1177/1934578x1000500910
[2] XIAO-NAN YANG. Metabolic Activation of Elemicin Leads to the Inhibition of Stearoyl-CoA Desaturase 1[J]. Chemical Research in Toxicology, 2019, 32 10: 1965-1976. DOI: 10.1021/acs.chemrestox.9b00112
Elemicin Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21600 | 55 |
| Chengdu Biopurify Phytochemicals Ltd. | +86-28-82633860; +8618080483897 | sales@biopurify.com | China | 3751 | 58 |
| Shanghai Standard Technology Co., Ltd. | 18502101150 | ft-sales@nature-standard.com | CHINA | 1923 | 58 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | factory@coreychem.com | China | 29795 | 58 |
| Wuhan ChemNorm Biotech Co.,Ltd. | +86-27-8439 4403 18971486879 | sales@chemnorm.com | CHINA | 2935 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354; +17819995354 | marketing@targetmol.com | United States | 32470 | 58 |
| ShanghaiFineBiotechCoLtd | +8618717800556 18717800556 | sales@finebioetch.com | CHINA | 318 | 58 |
| HANGZHOU LEAP CHEM CO., LTD. | +86-571-87711850 | market18@leapchem.com | China | 24727 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354; | support@targetmol.com | United States | 39042 | 58 |
| ShenZhen Trendseen Biological Technology Co.,Ltd. | 13417589054 | trendseenbio@gmail.com | China | 11681 | 58 |
View Lastest Price from Elemicin manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-01-13 | Elemicin
487-11-6
|
US $40.00 / mg | 96.27% | 10g | TargetMol Chemicals Inc. | ||
 |
2024-01-08 | Elemicin
487-11-6
|
US $9.00 / KG | 1KG | 99% | 50000tons | Wuhan Boyuan Import & Export Co., LTD | |
 |
2023-08-16 | Elemicin
487-11-6
|
US $140.00 / KG | 1KG | >99% | 50000kg/Month | Weijer International Trade (Hebei) Co., Ltd |
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