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Coumarin 120

Coumarin 120 structure

CAS No.: 26093-31-2

Chemical Name:: Coumarin 120

Synonyms: AMC;7-AMINO-4-METHYL-2H-CHROMEN-2-ONE;7-AMINO-4-METHYLCOUMARIN;C120;AMC 7-Amino-4-Methylcoumarin;2H-1-Benzopyran-2-one, 7-amino-4-methyl-;H-MCA;C 120;7-AMC;NSC 45796

CBNumber:: CB4354765

Molecular Formula:: C10H9NO2

Molecular Weight:: 175.18

MDL Number:: MFCD00006868

MOL File:: 26093-31-2.mol

MSDS File:: SDS

Last updated:2023-09-12 14:52:38

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Coumarin 120 Properties

Melting point	223-226 °C (lit.)
Boiling point	306.47°C (rough estimate)
Density	1.1999 (rough estimate)
refractive index	1.5060 (estimate)
storage temp.	2-8°C
solubility	Soluble in acetone (10 mg/ml) dimethyl sulfoxide (10 mg/ml) and dimethylformamide.
form	Crystalline Powder
pka	1.89 ± 0.20, most basic, temperature: 25 °C
color	Beige to brown
Sensitive	Light Sensitive
λmax	351 nm (MeOH); 342 nm (Buffer pH 7)
BRN	142231
Major Application	For authentification; dyelasers; color display devices; inks;monitoring underlying corrosion on coated aluminum;photoinitiating systems; recording materials;semiconductor devices; dye-sensitized solar cells(DSCs); mesoporous silica fibers; SiO2 sonogelhybrid materials; textiles; waveguides;whitening agents,
Biological Applications	Identifyingbacteria; measuring urinary kallikrein levels;monitoring platinum(iv) reduction and platinum(ii)reactions in cancer cells; as a substrate for measuringadipinylamidases activity, aromatic amino aciddecarboxylases activity, histone deacetylasesactivity, hydrolases/esterases activity,β-lactamases activity, microbial nitroreductasesactivity, penicillin G acylases activity,proteases/proteinases/peptidases activity,glutamyltransferases activity, tryptophanasesactivity; as an effective antitubercular agent; use astemperature sensor,
InChIKey	GLNDAGDHSLMOKX-UHFFFAOYSA-N
CAS DataBase Reference	26093-31-2(CAS DataBase Reference)
FDA UNII	OCY3JCT44X
NIST Chemistry Reference	Coumarin, 7-amino-4-methyl-(26093-31-2)
EPA Substance Registry System	2H-1-Benzopyran-2-one, 7-amino-4-methyl- (26093-31-2)

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS07

Signal word

Warning

Hazard statements

H315-H319-H335

Precautionary statements

P264-P280-P302+P352+P332+P313+P362+P364-P305+P351+P338+P337+P313-P261-P280a-P304+P340-P305+P351+P338-P405-P501a

Hazard Codes

Xi,Xn

Risk Statements

36/37/38-20/21/22

Safety Statements

26-36-37/39

WGK Germany

Hazard Note

Irritant

TSCA

Yes

HS Code

32049000

NFPA 704

	0
2		0

Coumarin 120 price More Price(69)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	257370	7-Amino-4-methylcoumarin 99%	26093-31-2	100mg	$58.9	2024-03-01	Buy
Sigma-Aldrich	164545	7-Amino-4-methylcoumarin	26093-31-2	10mg	$90.1	2024-03-01	Buy
TCI Chemical	M0760	7-Amino-4-methylcoumarin [for HPLC Labeling] >98.0%(HPLC)(T)	26093-31-2	1g	$135	2024-03-01	Buy
TCI Chemical	M0760	7-Amino-4-methylcoumarin [for HPLC Labeling] >98.0%(HPLC)(T)	26093-31-2	5g	$349	2024-03-01	Buy
Alfa Aesar	A15017	7-Amino-4-methylcoumarin, 98%	26093-31-2	1g	$109	2024-03-01	Buy

Product number	Packaging	Price	Buy
257370	100mg	$58.9	Buy
164545	10mg	$90.1	Buy
M0760	1g	$135	Buy
M0760	5g	$349	Buy
A15017	1g	$109	Buy

Coumarin 120 Chemical Properties,Uses,Production

Chemical Properties

Coumarin 120 is Light yellow beige powder

Uses

Coumarin 120 is widely used fluorophore, well-known for preparing fluorogenic substrates for cystine aminopeptidase and other hydrolases. Used as reference compound in enzyme assays.

Uses

λ max 354 nm in EthanolSuitable as laser dye and used as a fluorescent labeling reagent for trace determination of enzymes.

Uses

suitable for determining polygalacturonase activity

Definition

ChEBI: Coumarin 120 is a member of 7-aminocoumarins. It has a role as a fluorochrome.

General Description

7-Amino-4-methylcoumarin (coumarin120) is an aminocoumarin laser dye that can emit laser in the range of 370-760 nm. It has three intermolecular hydrogen bonded structures with C-H···O and N-H····O.

Biochem/physiol Actions

7-Amino-4-methylcoumarin is a coumarin derivative, which serves as a fluorescence reference standard to screen protease inhibitors.

storage

+4°C

Purification Methods

Dissolve it in 5% HCl, filter and basify with 2M ammonia. The precipitate is dried in a vacuum and recrystallised from dilute EtOH. It yields a blue solution and is light sensitive. [Sigler Synthesis 614 1980, Kanaoka et al. Chem Pharm Bull Jpn 30 1485 1982, Beilstein 18/11 V 445.]

Coumarin 120 Preparation Products And Raw materials

Raw materials

Ethyl acetoacetate Ethanol Ethyl chloroformate Ethyl acetate Acetic acid

Sodium hydroxide 3-Aminophenol PETROLEUM ETHER Sulfuric acid

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Preparation Products

Coumarin 120 Suppliers

Global( 426)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Hebei Yanxi Chemical Co., Ltd.	+8617531190177	peter@yan-xi.com	China	5993	58
Capot Chemical Co.,Ltd.	571-85586718 +8613336195806	sales@capotchem.com	China	29797	60
Henan Tianfu Chemical Co.,Ltd.	+86-0371-55170693 +86-19937530512	info@tianfuchem.com	China	21695	55
ATK CHEMICAL COMPANY LIMITED	+undefined-21-51877795	ivan@atkchemical.com	China	32480	60
Shanghai Zheyan Biotech Co., Ltd.	18017610038	zheyansh@163.com	CHINA	3620	58
career henan chemical co	+86-0371-86658258	sales@coreychem.com	China	29914	58
Hubei Jusheng Technology Co.,Ltd.	18871490254	linda@hubeijusheng.com	CHINA	28180	58
Accela ChemBio Inc.	(+1)-858-699-3322	info@accelachem.com	United States	19965	58
Xiamen AmoyChem Co., Ltd	+86-592-6051114 +8618959220845	sales@amoychem.com	China	6387	58
Chongqing Chemdad Co., Ltd	+86-023-61398051 +8613650506873	sales@chemdad.com	China	39916	58

Supplier	Advantage
Hebei Yanxi Chemical Co., Ltd.	58
Capot Chemical Co.,Ltd.	60
Henan Tianfu Chemical Co.,Ltd.	55
ATK CHEMICAL COMPANY LIMITED	60
Shanghai Zheyan Biotech Co., Ltd.	58
career henan chemical co	58
Hubei Jusheng Technology Co.,Ltd.	58
Accela ChemBio Inc.	58
Xiamen AmoyChem Co., Ltd	58
Chongqing Chemdad Co., Ltd	58

View Lastest Price from Coumarin 120 manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2023-09-12	7-Amino-4-methylcoumarin 26093-31-2	US $10.00-1.00 / kg	1kg	0.99	20 tons	Hebei Yanxi Chemical Co., Ltd.
2023-09-06	7-Amino-4-methylcoumarin 26093-31-2	US $0.00-0.00 / KG	1KG	99%	500000kg	Hebei Guanlang Biotechnology Co., Ltd.
2019-07-10	Coumarin 120 26093-31-2	US $8.80 / KG	1KG	97%-99%	100kg	Career Henan Chemical Co

7-Amino-4-methylcoumarin
26093-31-2
US $10.00-1.00 / kg
0.99
Hebei Yanxi Chemical Co., Ltd.

7-Amino-4-methylcoumarin
26093-31-2
US $0.00-0.00 / KG
99%
Hebei Guanlang Biotechnology Co., Ltd.

Coumarin 120
26093-31-2
US $8.80 / KG
97%-99%
Career Henan Chemical Co

Coumarin 120 Spectrum

Coumarin 120(26093-31-2)MS Coumarin 120(26093-31-2)¹HNMR Coumarin 120(26093-31-2)¹³CNMR Coumarin 120(26093-31-2)IR1 Coumarin 120(26093-31-2)Raman

26093-31-2(Coumarin 120)Related Search:

Lithium bis(trimethylsilyl)amide Betaine Dihydrocoumarin Methylparaben Acetonitrile

Kresoxim-methyl 4-Methylcumarin Methanol N,N-Dimethyl-1,4-phenylenediamine Paraquat dichloride

6-Methylcoumarin Tris(hydroxymethyl)aminomethane DICUMAROL 4-Methylumbelliferone Glycine

Methyl acetate Coumarin Methyl acrylate

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7-Amino-4-methyl-2H-chromen-2-one, 7-Amino-4-methyl-2-oxo-2H-chromene, 7-Amino-4-methyl-2-oxo-2H-1-benzopyran Coumarin 120, AMC (2S,5R,6R)-6-[(2R)-2-aMino-2-(4-hydroxyphenyl)acetaMido]-3,3-diMethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid 7-AMino-4-MethylcouMarin 7-AMino-4-MethylcouMarin, pure, 98% 1GR 7-AMino-4-MethylcouMarin 99% 7-Amino-4-methylcoumarin≥ 98% (HPLC) BUTTPARK 44\02-66 COUMARIN 440 COUMARIN 120 H-MCA 4-Methyl-7-aminocoumarin AKOS B014362 2H-1-Benzopyran-2-one,7-amino-4-methyl- 7-amino-4-methyl-2h-1-benzopyran-2-on 7-Amino-4-methyl-chromen-2-one 7-Amino-4-methylcoumarin, 99%, laser grade, pure 4-Methyl-7-amino-2H-1-benzopyran-2-one 7-Amino-4-methylcoumarin,99%,pure,laser grade TIMTEC-BB SBB008517 7-Amino-4-Methylcoumarin (AMC ) ,≥99% 7-Amino-4-methylcoumarin￡AMC120 7-Amino-4-methylcumarin C 120 Coumarin,7-amino-4-methyl- Cumarin120 7-AMINO-4-METHYLCOUMARIN 99% (LASER DY& 7-AMINO-4-METHYLCOUMARIN, FOR FLUOR-ESCE NCE 7-AMINO-4-METHYLCOUMARIN, 99% (LASER DYE ) 7-AMINO-4-METHYLCOUMARIN (AMC) 7-Amino-4-methyl-2H-1-benzopyran-2-one 7-Amino-4-methylcoumarin, laser grade, pure, 99% 7-Amino-4-methylcoumarin, pure, 98% 7-AMINO-4-METHYLCOUMARIN 98.5% MIN AMANTADINESULFATE AMC, 98.5% MIN. (4-Methyl-2-oxo-2H-chromen-7-yl)amine 7-AMC NSC 45796 7-Amino-4-methylcoumarin [for HPLC Labeling] 7-Amino-4-methylcoumarin, 98%, pure 7-Amino-4-methylcoumarin - CAS 26093-31-2 - Calbiochem Amino Labeling 7-Amino-4-methylcoumarin[forHPLCLabeling]> 7-Amino-4-Methylcoumarin (7-AMC) extrapure, 99% AMC [7-Amino-4-methylcoumarin] *CAS 26093-31-2* 7-Amino-4-methylcoumarin, 97.5% AMC 7-AMINO-4-METHYL-2H-CHROMEN-2-ONE 2H-1-Benzopyran-2-one, 7-amino-4-methyl- C120 AMC 7-Amino-4-Methylcoumarin 7-AMINO-4-METHYLCOUMARIN Coumarine120 Hymecromone Impurity 9 26093-31-2 Fluorescent Probes, Labels, Particles and Stains Fluorogenic