CHES
- CAS No.
- 103-47-9
- Chemical Name:
- CHES
- Synonyms
- CHES;2-(N-CYCLOHEXYLAMINO)ETHANESULPHONIC ACID;N-CycL;CHES),CH;CHES, 98+%;CHES, ULTROL;CHES ULTRAPURE;CHES free acid;CHES SIGMAULTRA;TIANFU-CHEM CHES
- CBNumber:
- CB4356976
- Molecular Formula:
- C8H17NO3S
- Molecular Weight:
- 207.29
- MDL Number:
- MFCD00003835
- MOL File:
- 103-47-9.mol
- MSDS File:
- SDS
| Product description | Number | Pack Size | Price |
| CHES BioUltra, ≥99.5% (T) | 29311 | 10g | $88.5 |
| CHES BioUltra, ≥99.5% (T) | 29311 | 50g | $243.1 |
| CHES,ULTROLGrade-CAS103-47-9-Calbiochem AzwitterionicbufferthatisusefulinthepH8.6-10.0range.HasapKaof9.15 | 239779 | 100g | $159 |
| CHES PharmaGrade, Manufactured under appropriate controls for use as a raw material in pharma or biopharmaceutical production., suitable for cell culture | RES1299C-B7 | 1pkg | $250 |
| OmniPur CHES - CAS 103-47-9 - Calbiochem | 3100-OP | 100g | $127 |
| More product size | |||
| Melting point | ≥300 °C |
|---|---|
| Density | 1.2045 (rough estimate) |
| vapor pressure | 0Pa at 25℃ |
| refractive index | 1.5364 (estimate) |
| storage temp. | Keep in dark place,Inert atmosphere,Room temperature |
| solubility | H2O: 0.5 M at 20 °C, clear, colorless |
| form | Solid |
| color | White |
| PH Range | 8.6 - 10.0 |
| PH | 3.0-5.0 (25℃, 0.5M in H2O) |
| pka | 9.3(at 25℃) |
| Odor | Odorless |
| Water Solubility | Soluble |
| Sensitive | Hygroscopic |
| λmax |
λ: 260 nm Amax: 0.08 λ: 280 nm Amax: 0.05 |
| Merck | 14,2055 |
| BRN | 2967601 |
| Stability | Stable. Incompatible with strong oxidizing agents. |
| InChI | 1S/C8H17NO3S.Na/c10-13(11,12)7-6-9-8-4-2-1-3-5-8;/h8-9H,1-7H2,(H,10,11,12);/q;+1/p-1 |
| InChIKey | MKWKNSIESPFAQN-UHFFFAOYSA-N |
| SMILES | [Na+].[S](=O)(=O)([O-])CCNC1CCCCC1 |
| LogP | -2.2 at 20℃ |
| CAS DataBase Reference | 103-47-9(CAS DataBase Reference) |
| FDA UNII | 71X53V3RZ1 |
| EPA Substance Registry System | Ethanesulfonic acid, 2-(cyclohexylamino)- (103-47-9) |
| Absorption |
≤0.05 at 280 in H2O at 0.5M ≤0.08 at 260 in H2O at 0.5M |
| UNSPSC Code | 12352200 |
| NACRES | NA.25 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H319 | |||||||||
| Precautionary statements | P280i-P305+P351+P338-P337+P313-P264-P280-P305+P351+P338+P337+P313 | |||||||||
| Hazard Codes | Xi,Xn | |||||||||
| Risk Statements | 36-20/22 | |||||||||
| Safety Statements | 26-28-24/25-16-60 | |||||||||
| WGK Germany | 3 | |||||||||
| F | 3 | |||||||||
| TSCA | TSCA listed | |||||||||
| HS Code | 29213099 | |||||||||
| Storage Class | 13 - Non Combustible Solids | |||||||||
| NFPA 704 |
|
CHES price More Price(56)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 29311 | CHES BioUltra, ≥99.5% (T) | 103-47-9 | 10g | $88.5 | 2025-07-31 | Buy |
| Sigma-Aldrich | 29311 | CHES BioUltra, ≥99.5% (T) | 103-47-9 | 50g | $243.1 | 2025-07-31 | Buy |
| Sigma-Aldrich | 239779 | CHES,ULTROLGrade-CAS103-47-9-Calbiochem AzwitterionicbufferthatisusefulinthepH8.6-10.0range.HasapKaof9.15 | 103-47-9 | 100g | $159 | 2025-07-31 | Buy |
| Sigma-Aldrich | RES1299C-B7 | CHES PharmaGrade, Manufactured under appropriate controls for use as a raw material in pharma or biopharmaceutical production., suitable for cell culture | 103-47-9 | 1pkg | $250 | 2022-05-15 | Buy |
| Sigma-Aldrich | 3100-OP | OmniPur CHES - CAS 103-47-9 - Calbiochem | 103-47-9 | 100g | $127 | 2022-05-15 | Buy |
CHES Chemical Properties,Uses,Production
Chemical Properties
White/clear cryst. powder
Uses
2-(Cyclohexylamino)ethanesulfonic acid (CHES) has been used in the preparation of dimethyl trisulfide- polysorbate 80 (DMTS-PS80) formulation.
Uses
CHES is zwitterionic buffer useful in pH range 8.6 to 10.0.CHES is widely utilized as a buffer which is used for investigations on pH-dependent processes in enzymology. It has been shown to have an unusually high affinity for the iodoacetate binding site of liver alcohol dehydrogenase.
Application
CHES belongs to the class of organic compounds known as cyclohexylamines. These are organic compounds containing a cyclohexylamine moiety, which consist of a cyclohexane ring attached to an amine group. It is often used as biological buffer. It can bind to hemagglutinin (HA) emulating with sialic acid (SA) and receptor binding site (RBS)-targeting broadly neutralizing antibodies.
Definition
ChEBI: N-cyclohexyl-2-aminoethanesulfonic acid is an alkanesulfonic acid that is cyclohexanamine in which one of the amino hydrogens is substituted by a 2-sulfoethyl group. It is used as a buffer (pH range of 8.6-10.0) for studying pH-dependent processes in enzymology. It has a role as a Good's buffer substance. It is an alkanesulfonic acid and a secondary aliphatic amine.
General Description
CHES (2-(N-cyclohexylamino)ethanesulphonic acid) is regarded as Good′s buffers for its self-buffering and biocompatible feature. It is used in protein stabilization and does not interact with metals.
Flammability and Explosibility
Not classified
CHES Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Jiangsu Boquan Biotechnology Co., Ltd. | +86-18168774353 | boquanshengwu003@boquansw.com | China | 248 | 58 |
| Suzhou Genemill Biotechnology Co.,Ltd | +8615862502491 | aimeegao@genemill.com | China | 39 | 58 |
| Hebei Yanxi Chemical Co., Ltd. | +8618531123677 | faithe@yan-xi.com | China | 5853 | 58 |
| Hebei Chuanghai Biotechnology Co,.LTD | +86-13131129325 | sales1@chuanghaibio.com | China | 5242 | 58 |
| Hebei Chuanghai Biotechnology Co., Ltd | +8615531151365 | mina@chuanghaibio.com | China | 18126 | 58 |
| Henan Bao Enluo International TradeCo.，LTD | +86-17331933971 | deasea125996@gmail.com | China | 2472 | 58 |
| Shaanxi Haibo Biotechnology Co., Ltd | +undefined18602966907 | qinhe02@xaltbio.com | China | 997 | 58 |
| Hebei Zhuanglai Chemical Trading Co Ltd | +86-16264648883 | niki@zlchemi.com | China | 7245 | 58 |
| Capot Chemical Co.,Ltd. | +86-（0）57185586718; +8613336195806 | sales@capot.com | China | 29735 | 60 |
| Shanghai Daken Advanced Materials Co.,Ltd | +86-2158073036 | info@dakenam.com | China | 13620 | 58 |
View Lastest Price from CHES manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-01-23 | N-Cyclohexyltaurine
103-47-9
|
US $0.00 / Kg/Drum | 1KG | 99%min | 500kgs | WUHAN FORTUNA CHEMICAL CO., LTD | |
 |
2025-12-24 | CHES
103-47-9
|
US $0.10 / KG | 1KG | 99.0% | 1000 tons | Shaanxi Dideu Medichem Co. Ltd | |
 |
2025-06-27 | N-Cyclohexyltaurine
103-47-9
|
US $0.00-0.00 / KG | 1KG | 99% | 500000kg | Hebei Chuanghai Biotechnology Co., Ltd |
-
- N-Cyclohexyltaurine
103-47-9
- US $0.00 / Kg/Drum
- 99%min
- WUHAN FORTUNA CHEMICAL CO., LTD
-
- CHES
103-47-9
- US $0.10 / KG
- 99.0%
- Shaanxi Dideu Medichem Co. Ltd
-
- N-Cyclohexyltaurine
103-47-9
- US $0.00-0.00 / KG
- 99%
- Hebei Chuanghai Biotechnology Co., Ltd
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